scholarly journals Polyetheretherketone(PEEK) rods versus titanium rods for lumbar fusion: a meta-analysis

2021 ◽  
Author(s):  
Wenhao Li ◽  
◽  
Yiqun Niu ◽  
He Zhao ◽  
Chuanhong Li ◽  
...  
Keyword(s):  
Lumbar Fusion ◽  
Meta Analysis ◽  
Peek Rods

scholarly journals Polyetheretherketone (PEEK) Rods for Lumbar Fusion: A Systematic Review and Meta-Analysis

10.14444/5027 ◽  
2018 ◽  
Vol 12 (2) ◽  
pp. 190-200 ◽  
Author(s):  
ABDULHAFEZ SELIM ◽  
SARAH MERCER ◽  
FENG TANG
Keyword(s):  
Systematic Review ◽  
Lumbar Fusion ◽  
Meta Analysis ◽  
Peek Rods

scholarly journals Meta-Analysis of Clinical Outcomes of Lumbar Fusion Surgical Interventions for Degenerative Spondylolisthesis

2018 ◽  
Vol 09 (07) ◽  
pp. 590-599
Author(s):  
Khaled Aneiba ◽  
Sabri Garoushi ◽  
Mohammed Elmajee ◽  
Mohamed Elsllabi ◽  
Osama A. Tashani
Keyword(s):  
Clinical Outcomes ◽  
Lumbar Fusion ◽  
Meta Analysis ◽  
Degenerative Spondylolisthesis ◽  
Surgical Interventions

P63. Current incidence of adjacent segment pathology following lumbar fusion versus motion preserving procedures: a systematic review and meta-analysis of recent projections

2020 ◽  
Vol 20 (9) ◽  
pp. S176
Author(s):  
Chester J. Donnally ◽  
Parthik Patel ◽  
Harsh Shah ◽  
Jose A. Canseco ◽  
Srikanth Divi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lumbar Fusion ◽  
Meta Analysis ◽  
Adjacent Segment ◽  
Current Incidence

scholarly journals Lumbar Fusion for Degenerative Disease: A Systematic Review and Meta-Analysis

Neurosurgery ◽  
2017 ◽  
Vol 80 (5) ◽  
pp. 701-715 ◽  
Author(s):  
Daniel Yavin ◽  
Steven Casha ◽  
Samuel Wiebe ◽  
Thomas E Feasby ◽  
Callie Clark ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cohort Studies ◽  
Spinal Stenosis ◽  
Lumbar Fusion ◽  
Meta Analysis ◽  
Current Evidence ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Safety And Efficacy ◽  
Relative Safety

Abstract BACKGROUND: Due to uncertain evidence, lumbar fusion for degenerative indications is associated with the greatest measured practice variation of any surgical procedure. OBJECTIVE: To summarize the current evidence on the comparative safety and efficacy of lumbar fusion, decompression-alone, or nonoperative care for degenerative indications. METHODS: A systematic review was conducted using PubMed, MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials (up to June 30, 2016). Comparative studies reporting validated measures of safety or efficacy were included. Treatment effects were calculated through DerSimonian and Laird random effects models. RESULTS: The literature search yielded 65 studies (19 randomized controlled trials, 16 prospective cohort studies, 15 retrospective cohort studies, and 15 registries) enrolling a total of 302 620 patients. Disability, pain, and patient satisfaction following fusion, decompression-alone, or nonoperative care were dependent on surgical indications and study methodology. Relative to decompression-alone, the risk of reoperation following fusion was increased for spinal stenosis (relative risk [RR] 1.17, 95% confidence interval [CI] 1.06-1.28) and decreased for spondylolisthesis (RR 0.75, 95% CI 0.68-0.83). Among patients with spinal stenosis, complications were more frequent following fusion (RR 1.87, 95% CI 1.18-2.96). Mortality was not significantly associated with any treatment modality. CONCLUSION: Positive clinical change was greatest in patients undergoing fusion for spondylolisthesis while complications and the risk of reoperation limited the benefit of fusion for spinal stenosis. The relative safety and efficacy of fusion for chronic low back pain suggests careful patient selection is required (PROSPERO International Prospective Register of Systematic Reviews number, CRD42015020153).

Comparative effectiveness of PEEK rods versus titanium alloy rods in lumbar fusion: A preliminary report

2013 ◽  
Vol 155 (7) ◽  
pp. 1187-1193 ◽  
Author(s):  
Lei Qi ◽  
Mu Li ◽  
Shuai Zhang ◽  
Jingsong Xue ◽  
Haipeng Si
Keyword(s):  
Titanium Alloy ◽  
Comparative Effectiveness ◽  
Preliminary Report ◽  
Lumbar Fusion ◽  
Peek Rods

Biomechanical Assessment of a PEEK Rod System for Semi-Rigid Fixation of Lumbar Fusion Constructs

2011 ◽  
Vol 133 (8) ◽  
Author(s):  
Matthew F. Gornet ◽  
Frank W. Chan ◽  
John C. Coleman ◽  
Brian Murrell ◽  
Russ P. Nockels ◽  
...  
Keyword(s):  
Lumbar Fusion ◽  
Dynamic Performance ◽  
Load Sharing ◽  
Axial Rotation ◽  
Rigid Fixation ◽  
Peek Rods ◽  
Significant Difference ◽  
Flexion Extension ◽  
Rod System

The concept of semi-rigid fixation (SRF) has driven the development of spinal implants that utilize nonmetallic materials and novel rod geometries in an effort to promote fusion via a balance of stability, intra- and inter-level load sharing, and durability. The purpose of this study was to characterize the mechanical and biomechanical properties of a pedicle screw-based polyetheretherketone (PEEK) SRF system for the lumbar spine to compare its kinematic, structural, and durability performance profile against that of traditional lumbar fusion systems. Performance of the SRF system was characterized using a validated spectrum of experimental, computational, and in vitro testing. Finite element models were first used to optimize the size and shape of the polymeric rods and bound their performance parameters. Subsequently, benchtop tests determined the static and dynamic performance threshold of PEEK rods in relevant loading modes (flexion-extension (F/E), axial rotation (AR), and lateral bending (LB)). Numerical analyses evaluated the amount of anteroposterior column load sharing provided by both metallic and PEEK rods. Finally, a cadaveric spine simulator was used to determine the level of stability that PEEK rods provide. Under physiological loading conditions, a 6.35 mm nominal diameter oval PEEK rod construct unloads the bone-screw interface and increases anterior column load (approx. 75% anterior, 25% posterior) when compared to titanium (Ti) rod constructs. The PEEK construct’s stiffness demonstrated a value lower than that of all the metallic rod systems, regardless of diameter or metallic composition (78% < 5.5 mm Ti; 66% < 4.5 mm Ti; 38% < 3.6 mm Ti). The endurance limit of the PEEK construct was comparable to that of clinically successful metallic rod systems (135N at 5 × 106 cycles). Compared to the intact state, cadaveric spines implanted with PEEK constructs demonstrated a significant reduction of range of motion in all three loading directions (> 80% reduction in F/E, p < 0.001; > 70% reduction in LB, p < 0.001; > 54% reduction in AR, p < 0.001). There was no statistically significant difference in the stability provided by the PEEK rods and titanium rods in any mode (p = 0.769 for F/E; p = 0.085 for LB; p = 0.633 for AR). The CD HORIZON® LEGACY™ PEEK Rod System provided intervertebral stability comparable to currently marketed titanium lumbar fusion constructs. PEEK rods also more closely approximated the physiologic anteroposterior column load sharing compared to results with titanium rods. The durability, stability, strength, and biomechanical profile of PEEK rods were demonstrated and the potential advantages of SRF were highlighted.

scholarly journals P.131 Lumbar fusion for degenerative disease: a systematic review and meta-analysis

2016 ◽  
Vol 43 (S2) ◽  
pp. S50-S50 ◽  
Author(s):  
D Yavin ◽  
AM Isaacs ◽  
S Casha ◽  
S Wiebe ◽  
TE Feasby ◽  
...  
Keyword(s):  
Spinal Stenosis ◽  
Lumbar Fusion ◽  
Meta Analysis ◽  
Practice Variation ◽  
Current Evidence ◽  
Bibliographic Databases ◽  
Safety And Efficacy ◽  
Random Effects Models ◽  
Relative Safety ◽  
Operative Care

Background: Lumbar fusion for degenerative indications is associated with a great degree of practice variation. We summarize the current evidence on the comparative safety and efficacy of lumbar fusion, decompression alone, or non-operative care for degenerative indications. Methods: Literature search of electronic bibliographic databases was conducted. Comparative studies reporting validated measures of safety or efficacy were included. Treatments effects were calculated through DerSimonian and Laird random effects models. Results: We retrieved 62 studies (17 randomized controlled, 15 prospective, 15 retrospective, and 15 registries), enrolling a total 302,347 adult patients. Disability, pain, and patient satisfaction following fusion, decompression alone, or non-operative care were dependent on surgical indications and study methodology. Relative to decompression alone, the risk of reoperation following fusion was increased for spinal stenosis (relative risk [RR] 1.17, 95% CI 1.06 to 1.30, p<0.004) and decreased for spondylolisthesis (RR 0.71, 95% CI 0.59 to 0.84, p<0.001). In all indications, complications were more frequent following fusion (RR 1.88, 95% CI 1.37 to 2.58, p<0.001). Mortality and treatment modality were not associated. Conclusions: Improvements were greatest in patients undergoing fusion for spondylolisthesis while complications limited the role of fusion for spinal stenosis. The relative safety and efficacy of fusion for chronic low back pain suggested careful patient selection is required.

scholarly journals Risk factors for adjacent segment degeneration after posterior lumbar fusion surgery in treatment for degenerative lumbar disorders: a meta-analysis

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Tao Wang ◽  
Wenyuan Ding
Keyword(s):  
Risk Factors ◽  
Lumbar Fusion ◽  
Meta Analysis ◽  
Adjacent Segment Degeneration ◽  
Cochrane Library ◽  
Adjacent Segment ◽  
Fusion Surgery ◽  
Posterior Lumbar Fusion ◽  
Lumbar Fusion Surgery ◽  
History Of

Abstract Study design A meta-analysis. Objective We performed a meta-analysis to explore the incidence and risk factors of adjacent segment degeneration (ASD) after posterior lumbar fusion surgery. Methods An extensive search of the literature was performed in English database of PubMed, Embase, and Cochrane Library, and Chinese database of CNKI and WANFANG (up to May 2020). We collected factors including demographic data, surgical factor, and sagittal parameters. Data analysis was conducted with RevMan 5.3 and STATA 12.0. Results Finally, 19 studies were included in the final analysis. In our study, the rate of ASD after posterior lumbar fusion surgery was 18.6% (540 of 2896). Our data also showed that mean age, body mass index (BMI), the history of smoking and hypertension, preoperative adjacent disc degeneration, long-segment fusion, preoperative superior facet violation, high lumbosacral joint angle, pre- and post-operative L1-S1 sagittal vertical axis (SVA), post-operative lumbar lordosis (LL), and preoperative pelvic incidence (PI) were associated with the development of ASD. However, gender, history of diabetes, bone mineral density (BMD), preoperative Oswestry Disability Index (ODI) and Japanese Orthopedic Association (JOA), the type of fusion (PLIF vs TLIF), type of bone graft (auto- vs allograft), fusion to S1(vs non-fusion to S1), diagnose (lumbar disc herniation, lumbar spinal stenosis, lumbar spondylolisthesis), preoperative pelvic tilt (PT), LL and sacral slope (SS), post-operative SS, PT and PI were not associated with the development of ASD. Conclusions In our study, many factors were correlated with the risk of ASD after posterior lumbar fusion surgery. We hope this article can provide a reference for spinal surgeons in treatment for lumbar degenerative diseases.

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