scholarly journals Prediction risk of complications and death in children with chronic hepatitis infection and extrahepatic manifestations

2015 ◽  
Vol 18 (2-3) ◽  
pp. 103-107
Author(s):  
Alice Nicoleta Azoicăi ◽  
◽  
Evelina Moraru ◽  
◽  
◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Hepatic Encephalopathy ◽  
Metabolic Diseases ◽  
Pediatric Population ◽  
Clinical Aspects ◽  
Extrahepatic Manifestations ◽  
Pediatric Clinic ◽  
Prediction Risk ◽  
Male Patients ◽  
Metabolic Type

Background. Cirhogenetic chronic evolution of these patients is related to the etiology, co-morbidities, the type of virus, the addition of metabolic diseases. Fibrosis markers of biological and clinical aspects must be permanently monitored. Materials and method. In a retrospective study we followed 40 patients diagnosed with cirrhosis, in the IInd Pediatric Clinic of the „Sf. Maria“ Emergency Hospital for Children in Iasi, between 2004-2014, out of 239 cases chronically infected recorded in this period of time. Results. The analysis of patients with extrahepatic manifestations showed no statistically significant differences, although the lack of seroconversion is more frequent in patients with extrahepatic manifestations versus those without (31.42% vs. 22.18%). The prospective study conducted in the pediatric population that was followed demonstrated that the risk of liver cirrhosis is by 3.03 times higher in male patients. The average age was 12.88 years, most children were diagnosed with liver cirrhosis after 10 years of age. The etiology predominant predisposing to development was HBV hepatitis, unlike hepatitis metabolic type, which has a milder trend. Conclusion. Complications detected included portal hypertension, ascites, pruritus, hepatic encephalopathy. In terms of frequency, itching had the largest share, followed by hepatic encephalopathy.

scholarly journals Clinical and Epidemiological Profile of Cirrhotic Patients at a Reference Center in Belém-PA, Analysis of 10 years

10.3823/2591 ◽  
2018 ◽  
Vol 11 ◽  
Author(s):  
Esther Castello Branco Mello Miranda ◽  
Fernanda Araújo Santos ◽  
Ana Rachel Koury Marinho ◽  
Mayara Castello Branco de Mello Dias ◽  
Suzana Maria Klautau Ferreira ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Retrospective Study ◽  
Medical Records ◽  
Hepatic Cirrhosis ◽  
Clinical Aspects ◽  
Cross Sectional ◽  
Reference Center ◽  
Cirrhotic Patients ◽  
Male Patients ◽  
Epidemiological Profile

Background: The aim of this study was to analyze the demographic, ethyological and clinical aspects of patients with liver cirrhosis treated in the Chronic Liver Disease Center. Methods: a descriptive, cross-sectional and retrospective study based on the analysis of 580 pacients’ medical records with the diagnosis of hepatic cirrhosis treated from 2004 to 2014 in Belém, Brazil. Conclusions: the profile was predominantly of male patients, aged between 51 and 60 years, coming from the capital ​​Belem, whose main etiologies of cirrhosis were C hepatitis and alcohol. Ascites was the most frequent clinical manifestation and Child-Pugh score A was the most prevalent.

scholarly journals RIFAXIMIN EFFECTIVENESS IN PREVENTING THE RECURRENCE OF HEPATIC ENCEPHALOPATHY AMONG PATIENTS WITH LIVER CIRRHOSIS

2021 ◽  
Vol 71 (4) ◽  
pp. 1296-99
Author(s):  
Muhammad Zulqurnain Saleem ◽  
Muhammad Hasan Saleem ◽  
Husnain Saleem ◽  
Muhammad Ali Aasil
Keyword(s):  
Liver Cirrhosis ◽  
Hepatic Encephalopathy ◽  
Conventional Treatment ◽  
Case Series ◽  
Military Hospital ◽  
P Value ◽  
Standard Regimen ◽  
Significant Difference ◽  
Study Population ◽  
Male Patients

Objective: To determine the effectiveness of rifaximin in reducing the frequency of recurrence of hepatic encephalopathy among patients with liver cirrhosis. Study Design: Descriptive case series. Place and Duration of Study: Outpatient department of Combined Military Hospital Peshawar from Jan to Jun 2017. Methodology: We included one hundred patients of either gender having liver cirrhosis with child Pugh B or C class with at least two previous episodes of hepatic encephalopathy. Patients were followed for six months to have any recurrence of hepatic encephalopathy. Conventional group was defined as having standard regimen including lactulose. Rifaximin treatment was defined as a 550mg BD daily dosing along with standard prescription. Results: Fifty patients were on conventional treatment to prevent recurrence of hepatic encephalopathy while 50 patients were using rifaximin in addition to standard prescription. The average age of 54.8 ± 6.1 years with 58% male patients and 48% in child-pugh B class. Thirty (30%) patients developed hepatic encephalopathy among the study population. 14 patients with recurrence belong to rifaximin group while 16 were on conventional treatment (p-value >0.05) showing a non-significant difference. Post stratification revealed only age as a significant predictor of recurrence of hepatic encephalopathy in our study population (p<0.05). Conclusion: Frequency of hepatic encephalopathy is similar in conventional treatment with Lactulose over six months of follow up as compared with rifaximin.

The Frequency of Random Findings on Abdominal / Pelvis Computed Tomography in Pediatric Trauma Patients

2020 ◽  
Vol 16 ◽  
Author(s):  
Betül Tiryaki Baştuğ
Keyword(s):  
Computed Tomography ◽  
Incidental Findings ◽  
Pediatric Population ◽  
Pediatric Trauma ◽  
Trauma Patients ◽  
Injured Child ◽  
Level 3 ◽  
Male Patients ◽  
Clinically Significant ◽  
Discharge Summaries

Aims: In this study, we aimed to find the percentage of random pathologies and abdominopelvic region anomalies that are not related to trauma in pediatric patients. Background: An abdominal assessment of an injured child usually involves computed tomography imaging of the abdomen and pelvis (CTAP) to determine the presence and size of injuries. Imaging may accidentally reveal irrelevant findings. Objectives: Although the literature in adults has reviewed the frequency of discovering these random findings, few studies have been identified in the pediatric population. Methods: Data on 142( 38 female, 104 male) patients who underwent CTAP during their trauma evaluation between January 2019 and January 2020 dates were obtained from our level 3 pediatric trauma center trauma records. The records and CTAP images were examined retrospectively for extra traumatic pathologies and anomalies. Results: 67 patients (47%) had 81 incidental findings. There were 17 clinically significant random findings. No potential tumors were found in this population. Conclusion: Pediatric trauma CTAP reveals random findings. For further evaluation, incidental findings should be indicated in the discharge summaries.

scholarly journals Innumerable cerebral microbleeds in hepatitis B virus-related decompensated liver cirrhosis: a case report

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chi Hyuk Oh ◽  
Jin San Lee
Keyword(s):  
Liver Cirrhosis ◽  
Hepatic Encephalopathy ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Brain Mri ◽  
Cerebral Microbleeds ◽  
Amyloid Angiopathy ◽  
Decompensated Liver Cirrhosis ◽  
B Virus ◽  
The Brain

Abstract Background Cerebral microbleeds (CMBs) are small, rounded, dark-signal lesions on brain MRI that represent cerebral hemosiderin deposits resulting from prior microhemorrhages and are neuroimaging biomarkers of cerebral amyloid angiopathy (CAA). Here, we report a case of innumerable CMBs in a patient with hepatic encephalopathy underlying decompensated liver cirrhosis. Case presentation An 83-year-old woman diagnosed with hepatitis B virus-related liver cirrhosis 40 years before was referred to our neurology clinic for progressive disorientation of time and place, personality changes, and confusion with somnolence over 2 weeks. Based on the laboratory, neuroimaging, and electrophysiological findings, we diagnosed the patient with hepatic encephalopathy, and her symptoms recovered within 12 h after proper medical management. Brain MRI showed innumerable CMBs in the bilateral frontal, parietal, temporal, and occipital lobes. Since the distribution of CMBs in the patient was mainly corticosubcortical and predominantly in the posterior cortical regions, and the apolipoprotein E genotype was ε4/ε4, we speculated that CAA and hepatic encephalopathy coexisted in this patient. Conclusions We suggest that severe liver dysfunction associated with long-term decompensated liver cirrhosis may be related to an increased number of CMBs in the brain. Our findings indicate that decompensated liver cirrhosis may be a risk factor for the development of CMBs and corroborate a link between the liver and the brain.

scholarly journals L-Carnitine for the Treatment of Overt Hepatic Encephalopathy in Patients with Advanced Liver Cirrhosis

2018 ◽  
Vol 64 (5) ◽  
pp. 321-328 ◽  
Author(s):  
Kazuto TAJIRI ◽  
Yuka FUTSUKAICHI ◽  
Saito KOBAYASHI ◽  
Satoshi YASUMURA ◽  
Terumi TAKAHARA ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Hepatic Encephalopathy ◽  
Overt Hepatic Encephalopathy ◽  
Advanced Liver Cirrhosis

Sarcopenia predicts minimal hepatic encephalopathy in patients with liver cirrhosis

2017 ◽  
Vol 47 (13) ◽  
pp. 1359-1367 ◽  
Author(s):  
Tatsunori Hanai ◽  
Makoto Shiraki ◽  
Satoshi Watanabe ◽  
Takahiro Kochi ◽  
Kenji Imai ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Hepatic Encephalopathy ◽  
Minimal Hepatic Encephalopathy

scholarly journals Diagnosis of Growing Pain in Bangladeshi Pediatric Population

2013 ◽  
Vol 5 (1) ◽  
pp. 46-48 ◽  
Author(s):  
Santosh Kumar Saha ◽  
Aditi Modak ◽  
Kamrunnahar Chowdhury ◽  
Md Saleh Uddin ◽  
Dilip Kumar Ghosh ◽  
...  
Keyword(s):  
Heart Disease ◽  
Rheumatic Fever ◽  
Pediatric Population ◽  
Accurate Diagnosis ◽  
Clinical Aspects ◽  
Limb Pain ◽  
Diagnostic Challenge ◽  
Growing Period ◽  
Frequent Site ◽  
Slow Growing

Background: Unexplained limb pain is a major diagnostic challenge. Parents become very much worried as their physician are not sure regarding accurate diagnosis of unexplained limb pain. Majority of the limb pain are due to Growing pain which can be diagnosed by using Standard Criteria. Objectives: The purpose of the present study was to see the clinical aspects of growing pain and to determine the causes of unexplained limb pain. Methodology: This study prospectively examined the presence of growing pain in a self reported population of children with limb pain of unexplained etiology attending National Center for Control of Rheumatic Fever and Heart Disease over the period of 6 months. Results: Total 57 children of 3-12 yrs of age were enrolled in this study and out of them 43(75.4%) were diagnosed as Growing Pain. Mean age of growing pain was 7.77(2.66). 19 children (44.2%) were male and 24 (55.8%) were female. Most frequent site of pain was calf (65.1%) and 95% cases pain occur at night. Growing Pain usually occur at slow growing period (86%) than rapid growing period (14%). Conclusion: Majority of unexplained limb pain are growing pain which is benign. DOI: http://dx.doi.org/10.3329/jssmc.v5i1.16251 J Shaheed Suhrawardy Med Coll, 2013;5(1):46-48

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