scholarly journals Rehabilitation therapy in patients with psoriatic arthritis after SARS-CoV-2 infection

2021 ◽  
Vol 30 (3) ◽  
pp. 110-114
Author(s):  
Diana Maghiar ◽  
◽  
Nicoleta Anamaria Pascalau ◽  
Liviu Lazar ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psoriatic Arthritis ◽  
Pain Scale ◽  
Important Change ◽  
Emotional Impact ◽  
Rehabilitation Treatment ◽  
Rehabilitation Therapy ◽  
Social And Emotional ◽  
Beneficial Effects

Objectives. We want to present the evolution of a lot of patients, previously diagnosed with psoriatic arthritis, who last spring went through a difficult period due to infection with the new coronavirus. After healing from COVID-19, the patients had returned to the hospital after a period of 4-6 months, to follow a rehabilitation treatment, the majority of the accusations being those related to psoriatic arthritis, with close follow-up of these patients in connection with the treatment applied. Material and methods. The patients were evaluated at hospitalization (biological inflammatory markers like CRP and ESR), pain scale, DAPSA score, PASI and the quality of life score (DLQI and QOL scale), after which they followed different rehabilitation treatments for a period of 21 days. After 3 months of completing this treatment they were re-evaluated. Patients diagnosed with psoriatic arthritis who do not have documentation to suggest SARS-CoV-2 infection (antibodies/ previous RT-PCR positive tests) were not included in the study. Outcomes. There were some significant differences in terms of the initial score at hospitalization and that performed after rehabilitation treatment. Most of the indices performed had lower values at reassessment (pain scale score, DAPSA, PASI, DLQI and even lower values of CRP and ESR), thus resulting in an important step in terms of the beneficial effects of rehabilitation therapy, both for patients with psoriatic arthritis and for post-COVID-19 recovery. The most important change was observed in the score for quality of life. Conclusions. The inclusion of rehabilitation therapy in patients with psoriatic arthritis should be a step that each patient should take. Its effects are long-term, with periods of pain decreasing in frequency and intensity, thus changing the quality of life of these patients. The mental, social and emotional impact of COVID-19 on people who have gone through the disease can be changed in a good way, also following a rehabilitation therapy.

scholarly journals Rehabilitation therapy in patients with psoriatic arthritis after SARS-CoV-2 infection

2021 ◽  
Vol 30 (3) ◽  
pp. 110-114
Author(s):  
Diana Maghiar ◽  
◽  
Nicoleta Anamaria Pascalau ◽  
Liviu Lazar ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psoriatic Arthritis ◽  
Pain Scale ◽  
Important Change ◽  
Emotional Impact ◽  
Rehabilitation Treatment ◽  
Rehabilitation Therapy ◽  
Social And Emotional ◽  
Beneficial Effects

Objectives. We want to present the evolution of a lot of patients, previously diagnosed with psoriatic arthritis, who last spring went through a difficult period due to infection with the new coronavirus. After healing from COVID-19, the patients had returned to the hospital after a period of 4-6 months, to follow a rehabilitation treatment, the majority of the accusations being those related to psoriatic arthritis, with close follow-up of these patients in connection with the treatment applied. Material and methods. The patients were evaluated at hospitalization (biological inflammatory markers like CRP and ESR), pain scale, DAPSA score, PASI and the quality of life score (DLQI and QOL scale), after which they followed different rehabilitation treatments for a period of 21 days. After 3 months of completing this treatment they were re-evaluated. Patients diagnosed with psoriatic arthritis who do not have documentation to suggest SARS-CoV-2 infection (antibodies/ previous RT-PCR positive tests) were not included in the study. Outcomes. There were some significant differences in terms of the initial score at hospitalization and that performed after rehabilitation treatment. Most of the indices performed had lower values at reassessment (pain scale score, DAPSA, PASI, DLQI and even lower values of CRP and ESR), thus resulting in an important step in terms of the beneficial effects of rehabilitation therapy, both for patients with psoriatic arthritis and for post-COVID-19 recovery. The most important change was observed in the score for quality of life. Conclusions. The inclusion of rehabilitation therapy in patients with psoriatic arthritis should be a step that each patient should take. Its effects are long-term, with periods of pain decreasing in frequency and intensity, thus changing the quality of life of these patients. The mental, social and emotional impact of COVID-19 on people who have gone through the disease can be changed in a good way, also following a rehabilitation therapy.

Social and Emotional Impact of Strabismus Surgery on Quality of Life in Children

2005 ◽  
Vol 9 (2) ◽  
pp. 148-151 ◽  
Author(s):  
Steven M. Archer ◽  
David C. Musch ◽  
Patricia A. Wren ◽  
Kenneth E. Guire ◽  
Monte A. Del Monte
Keyword(s):  
Quality Of Life ◽  
Strabismus Surgery ◽  
Emotional Impact ◽  
Social And Emotional

scholarly journals Quality of life in patients with psoriatic arthritis

2021 ◽  
Vol 97 (3) ◽  
pp. 56-65
Author(s):  
Kseniya Mikhailovna Koreshkova ◽  
Zarema Rimovna Khismatullina
Keyword(s):  
Quality Of Life ◽  
Psoriatic Arthritis ◽  
Emotional Disorders ◽  
Pain Syndrome ◽  
Point Of View ◽  
Women Patients ◽  
Social And Emotional ◽  
Rate Of Progression ◽  
Standing Up

Currently, the prevalence of PsA in the population is 0.05-1.6%. In terms of the rate of progression, deterioration of the quality of life and disability, PsA patients are comparable to rheumatoid arthritis and ankylosing spondylitis. Purpose: to study the effect of psoriatic arthritis on the quality of life of patients. Materials and methods. A study was conducted with the participation of 75 patients. For the study, we used standardized questionnaires developed to assess the quality of life of patients with PsA. Research method - questioning patients using standardized questionnaires, analysis of the information received. Results. Psoriatic arthritis has a significant impact on the quality of life of patients, affecting the physical, social and emotional spheres. The most important areas of influence of psoriatic arthritis from the point of view of patients are: pain (78%), skin problems (72%), decreased functionality (60%), discomfort (51%) and fatigue (44%). In patients with PsA, pronounced functional disorders are noted. The HAQ index in men averaged 1.98 0.86 (from 1.12 to 2.84 points), in women - 1.77 0.34 (from 1.44 to 2.11 points) (p 0.0001). The pain syndrome according to the VAS averaged 74.34 9.22 mm in men, and 65.77 8.19 mm in women. Patients noted the greatest disturbances in such activities as walking (44%), standing up (37%), hygiene procedures (21%), using transport (36%), housework (47%). Almost 40% of patients use various devices or the help of others (p 0.0001). Psoriatic arthritis also affects the emotional sphere of life. Subclinical emotional disorders were more often detected in women than in men (symptoms of anxiety - 61.9% and 42.2%, depression - 71.4% and 39.4%, respectively); however, approximately the same number of men had clinically expressed signs of depression ( 12.1%) and women (11.9%). Psoriatic arthritis significantly reduces the quality of life, affecting the most important aspects of it - physical, emotional and social.

scholarly journals The effect of intravenous golimumab on health-related quality of life and work productivity in patients with active psoriatic arthritis: results of the Phase 3 GO-VIBRANT trial

2021 ◽  
Author(s):  
Alexis Ogdie ◽  
Jessica A. Walsh ◽  
Soumya D. Chakravarty ◽  
Steven Peterson ◽  
Kim Hung Lo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psoriatic Arthritis ◽  
Disease Activity ◽  
Productivity Loss ◽  
Health Related Quality ◽  
Functional Capability ◽  
Related Quality ◽  
Health Related ◽  
Eq Vas

Abstract Introduction/objectives To evaluate changes in health-related quality of life (HRQoL) and productivity following treatment with intravenous (IV) golimumab in patients with psoriatic arthritis (PsA). Methods Patients were randomized to IV golimumab 2 mg/kg (n=241) at Weeks 0, 4, then every 8 weeks (q8w) through Week 52 or placebo (n=239) at Weeks 0, 4, then q8w, with crossover to IV golimumab 2 mg/kg at Weeks 24, 28, then q8w through Week 52. Change from baseline in EuroQol-5 dimension-5 level (EQ-5D-5L) index and visual analog scale (EQ-VAS), daily productivity VAS, and the Work Limitations Questionnaire (WLQ) was assessed. Relationships between these outcomes and disease activity and patient functional capability were evaluated post hoc. Results At Week 8, change from baseline in EQ-5D-5L index (0.14 vs 0.04), EQ-VAS (17.16 vs 3.69), daily productivity VAS (−2.91 vs −0.71), and WLQ productivity loss score (−2.92 vs −0.78) was greater in the golimumab group versus the placebo group, respectively. At Week 52, change from baseline was similar in the golimumab and placebo-crossover groups (EQ-5D-5L index: 0.17 and 0.15; EQ-VAS: 21.61 and 20.84; daily productivity VAS: −2.89 and −3.31; WLQ productivity loss: −4.49 and −3.28, respectively). HRQoL and productivity were generally associated with disease activity and functional capability, with continued association from Week 8 through Week 52. Conclusion IV golimumab resulted in early and sustained improvements in HRQoL and productivity from Week 8 through 1 year in patients with PsA. HRQoL and productivity improvements were associated with improvements in disease activity and patient functional capability. Key Points• In patients with active psoriatic arthritis (PsA), intravenous (IV) golimumab improved health-related quality of life (HRQoL) and productivity as early as 8 weeks and maintained improvement through 1 year• Improvements in HRQoL and productivity outcomes in patients with PsA treated with IV golimumab were associated with improvements in disease activity and patient functional capability outcomes• IV golimumab is an effective treatment option for PsA that can mitigate the negative effects of the disease on HRQoL and productivity

The Association Between IL17, Fatigue and Quality of Life in Psoriatic Arthritis Patients.

2021 ◽  
Author(s):  
Souzan Ezzat Gado ◽  
Radwa Moustafa EL-khouly ◽  
Marwa Ahmad Aboelhawa ◽  
Mohamed Hassan Fouda ◽  
Hanaa Samy El-Banna
Keyword(s):  
Quality Of Life ◽  
Psoriatic Arthritis

scholarly journals Quality of Life following Chemoradiotherapy for Localized Muscle Invasive Bladder Carcinoma: A Systematic Review

2021 ◽  
pp. 1-13
Author(s):  
Ben-Max De Ruiter ◽  
Abel N. Keijzer ◽  
Maarten C.C.M. Hulshof ◽  
Adriaan D. Bins ◽  
Theo M. de Reijke ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sexual Function ◽  
Bladder Carcinoma ◽  
Bowel Function ◽  
Definitive Treatment ◽  
Cochrane Library ◽  
Social And Emotional ◽  
Muscle Invasive ◽  
The Impact

BACKGROUND: Health related Quality of Life (HRQoL) is an important factor regarding treatment for localized Muscle Invasive Bladder Carcinoma (MIBC), as it may affect choice of treatment. The impact of chemoradiotherapy (CRT) for MIBC on HRQoL has not yet been well-established. OBJECTIVE: To systematically evaluate evidence regarding HRQoL as assessed by validated questionnaires after definitive treatment with CRT for localized MIBC. METHODS: We performed a critical review of PubMed/MEDLINE, EMBASE, and the Cochrane Library in October 2020. Two reviewers independently screened articles for eligibility and assessed the methodological quality of the included articles using Joanna Briggs Institute critical appraisal tools. A narrative synthesis was undertaken. RESULTS: Of 579 articles identified, 11 studies were eligible for inclusion, including three RCTs and 8 non-randomized studies, reporting on HRQoL data for 606 CRT patients. Global health declined at End of treatment (EoT), and recovered 3 months following treatment. Physical function declined from baseline at EoT and recovered between 3 and 24 months and was maintained at 5 years follow up. CRT had little effect on social and emotional function in the short-term, but HRQoL results in the long-term were lower compared to the general population. Urinary function declined from baseline at EoT, but returned to baseline at 6 months following CRT. After initial decline in bowel function, a complete return to baseline occurred 4 years following treatment. The majority of studies assessing sexual function showed no to little effect on sexual function. CONCLUSIONS: HRQoL recovers to baseline within 3 months to 2 years in almost all domains. The amount of available evidence regarding HRQoL following CRT for MIBC is limited and the quality of evidence is low.

scholarly journals Glatiramer Acetate Treatment in Multiple Sclerosis-Associated Fatigue—Beneficial Effects on Self-Assessment Scales But Not on Molecular Markers

Biomolecules ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 393
Author(s):  
Oliver Neuhaus ◽  
Wolfgang Köhler ◽  
Florian Then Bergh ◽  
Wolfgang Kristoferitsch ◽  
Jürgen Faiss ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Glatiramer Acetate ◽  
Neurotrophic Factors ◽  
Common Symptom ◽  
Mrna Levels ◽  
Open Label ◽  
Immunological Parameters ◽  
Beneficial Effects

Although fatigue is a common symptom in multiple sclerosis (MS), its pathomechanisms are incompletely understood. Glatiramer acetate (GA), an immunomodulatory agent approved for treatment of relapsing-remitting MS (RRMS), possesses unique mechanisms of action and has been shown to exhibit beneficial effects on MS fatigue. The objective of this study was to correlate clinical, neuropsychological, and immunological parameters in RRMS patients with fatigue before and during treatment with GA. In a prospective, open-label, multicenter trial, 30 patients with RRMS and fatigue were treated with GA for 12 months. Inclusion criterion was the presence of fatigue as one of the most frequent and disabling symptoms. Before and during treatment, fatigue was assessed using the Fatigue Severity Scale (FSS), the MS-FSS, and the Modified Fatigue Impact Scale (MFIS). In addition, fatigue and quality of life were assessed using the Visual Analog Scales (VAS). Laboratory assessments included screening of 188 parameters using real-time PCR microarrays followed by further analysis of several cytokines, chemokines, and neurotrophic factors. Fatigue self-assessments were completed in 25 patients. After 12 months of treatment with GA, 13 of these patients improved in all three scales (with the most prominent effects on the MFIS), whereas 5 patients had deteriorated. The remaining 7 patients exhibited inconsistent effects within the three scales. Fatigue and overall quality of life had improved, as assessed via VAS. Laboratory assessments revealed heterogeneous mRNA levels of cytokines, chemokines, and neurotrophic factors. In conclusion, we were not able to correlate clinical and molecular effects of GA in patients with RRMS and fatigue.

Therapeutic Affordances of Social Media and Associated Quality of Life Outcomes in Young Adults

2021 ◽  
pp. 089443932110329
Author(s):  
Paul Dodemaide ◽  
Mark Merolli ◽  
Nicole Hill ◽  
Lynette Joubert
Keyword(s):  
Quality Of Life ◽  
Social Media ◽  
Young Adults ◽  
Well Being ◽  
Evidence Base ◽  
Social And Emotional ◽  
Perceived Quality Of Life ◽  
Use Of Social Media ◽  
The Relationship

There is a growing body of literature exploring the general population’s use of social media for assistance in dealing with stigmatized health issues. This study presents novel research examining the relationship between social media use and young adults. It utilizes a therapeutic affordance (TA) framework. Quantitative results from this study are complemented by qualitative data. The relationships between distinct social media and their TA (a–b) are presented to highlight their potential to impact positively on social and emotional well-being outcomes. Evidence includes broad support for “connection,” “narration,” and “collaboration” TAs in this context and the relationship between the use of distinct social media and perceived quality of life (QOL) outcomes (a–c). TA provides an appropriate and valuable theoretical framework which is useful for the development of an evidence-base from the analysis of young adult’s social media usage. An analysis of the association between social media and their QOL outcomes is presented according to the TA relationship pathway (a–c–b). The adoption of a TA framework enables a nuanced analysis of significant associations between specific social media, TA, and improved QOL outcomes. This study demonstrates the significant association between social media and perceived QOL outcomes in young adults.

scholarly journals The Attention of Caregiver. An Intersdisciplinary Vision

2011 ◽  
Vol 1 (3) ◽  
pp. 105-118
Author(s):  
Esther Secanilla ◽  
María Bonjoch ◽  
Margarida Galindo ◽  
Laura Gros
Keyword(s):  
Quality Of Life ◽  
Emotional Wellbeing ◽  
Educational Training ◽  
Social And Emotional ◽  
Validated Questionnaire ◽  
People With Dementia ◽  
Active Observation ◽  
Admission Interviews ◽  
Social And Emotional Wellbeing

In a global approach to the attention of carers of older people with dementia living at the elder’s home, it is essential to promote their personal, social and emotional wellbeing as well as provide them with tools that improve their quality of life. With this goal we present the experience of CDD and Residencia de Horta, Barcelona. A documentary review of the file was made, covering the period between 2004 and 2010 to define the sample. For the analysis of the semistructured admission interviews, monitoring and mentoring, a research was made through the daily records. Other strategies used were fulfilment questionnaires as well as the validated questionnaire of caregiver’s burden (Zarit and Zarit, 1982). Likewise, there was a systematic active observation of the GAM group. The interviews were made to the caregivers who attended the GAM. It is proven that actions of prevention and monitoring as well as psycho-educational training designed for carers promotes the user’s staying at their home, improves their quality of life and their caregiver’s.

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