IMPORTANCE OF THE OXIDATION REACTION OF SODIUM METAPERIODATE FOR SPECTROPHOTOMETRIC ASSAY OF RESERPINE
Keyword(s):
A new simple, accurate and reasonably sensitive spectrophotometric method is described for the determination of reserpine based on the oxidation with sodium metaperiodate in the presence of acetic acid and coupling with 3-methyl-2-benzo thiazolinone hydazone hydrochloride (MBTH) to form highly blue coloured product showing maximum absorbance at 630 nm. Beer's law is obeyed in the range 0.2–1.6 µg ml−1. The relative standard deviation was found to be less than 1%. The proposed method can be applied for the estimation of reserpine in tablets with no evidence of interference from excipients.
1997 ◽
Vol 80
(2)
◽
pp. 388-391
◽
1993 ◽
Vol 76
(3)
◽
pp. 601-603
◽
2008 ◽
Vol 27
(2)
◽
pp. 149
◽
2004 ◽
Vol 87
(4)
◽
pp. 847-851
◽
2012 ◽
Vol 554-556
◽
pp. 926-933
1970 ◽
Vol 7
(5)
◽
pp. 25-29
2010 ◽
Vol 113-116
◽
pp. 1732-1734
2017 ◽
Vol 18
(1)
◽
pp. 25