scholarly journals Treatment outcomes and prognostic factors in uterine cervical cancer patients treated with postoperative extended field radiation therapy

2009 ◽  
Vol 20 (4) ◽  
pp. 227 ◽  
Author(s):  
Hak Jae Kim ◽  
Sung Whan Ha ◽  
Hong-Gyun Wu
Oncotarget ◽  
2017 ◽  
Vol 8 (68) ◽  
pp. 112855-112866 ◽  
Author(s):  
Masaharu Hata ◽  
Izumi Koike ◽  
Etsuko Miyagi ◽  
Reiko Numazaki ◽  
Mikiko Asai-Sato ◽  
...  

Author(s):  
Kazuki Ishikawa ◽  
Tsuneo Yamashiro ◽  
Takuro Ariga ◽  
Takafumi Toita ◽  
Wataru Kudaka ◽  
...  

Abstract Purpose Fractures are known to shorten life expectancy and worsen the quality of life. The risk of fractures after radiation therapy in cervical cancer patients is known to be multifactorial. In this study, we examined risk factors for fractures in cervical cancer patients, especially by evaluating bone densities and DVH parameters for fractured bones. Materials and Methods For 42 patients, clinical characteristics, pretreatment CT bone densities, and radiation dose were compared between patients with and without fractures. Results Posttreatment fractures occurred in 25 bones among ten patients. Pretreatment CT bone densities were significantly lower in patients with fractures (P < 0.05–0.01 across sites, except for the ilium and the ischium). Although DVH parameters were also significantly associated with fractures in univariate analysis, only CT densities were significantly associated with fractures in multivariate analysis. Conclusion Pretreatment CT densities of spinal and pelvic bones, which may reflect osteoporosis, have a significant impact on the risk for posttreatment fractures.


2017 ◽  
Vol 35 (3) ◽  
pp. 241-248 ◽  
Author(s):  
Doo Yeul Lee ◽  
Sung Ho Moon ◽  
Kwan Ho Cho ◽  
Tae Hyun Kim ◽  
Moon Soo Kim ◽  
...  

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