The Prevalence of Type-Specific Human Papillomaviral DNA in the Female Genital Tract using Self Sampling Device and Its Clinical Significance to Predict the Risk of Cervical Cancer

1991 ◽  
Vol 2 (1) ◽  
pp. 18
Author(s):  
Sang Gyun Han ◽  
Seong Jo Kim
Keyword(s):  
Cervical Cancer ◽  
Clinical Significance ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Sampling Device ◽  
Female Genital

scholarly journals Microbiome and Cervical Cancer

Pathobiology ◽  
2020 ◽  
pp. 1-11
Author(s):  
Cristina Paula Castanheira ◽  
Mayara Luciana Sallas ◽  
Rafaella Almeida Lima Nunes ◽  
Noely Paula Cristina Lorenzi ◽  
Lara Termini
Keyword(s):  
Cervical Cancer ◽  
Genital Tract ◽  
Current Knowledge ◽  
Disease Onset ◽  
Female Genital Tract ◽  
Hpv Infection ◽  
Vaginal Microbiome ◽  
Associated Lesions ◽  
Cervical Disease ◽  
Female Genital

Persistent infection with some types of mucosal human papillomavirus (HPV) is the etiological factor for the development of cervical cancer and its precursor lesions. Besides, several cofactors are known to play a role in cervical disease onset and progression either by favoring or by preventing HPV infection and persistence. The microbiome of a healthy female genital tract is characterized by the presence of 1 or few varieties of lactobacilli. However, high-throughput studies addressing the bacterial diversity and abundance in the female genital tract have shown that several factors, including hormonal levels, hygiene habits, and sexually transmitted diseases may disrupt the natural balance, favoring the outgrowth of some groups of bacteria, which in turn may favor some pathological states. Recently, the vaginal microbiome has emerged as a new variable that could greatly influence the natural history of HPV infections and their clinical impact. In this context, changes in the vaginal microbiome have been detected in women infected with HPV and women with HPV-associated lesions and cancer. However, the role of specific bacteria groups in the development/progression or prevention/regression of HPV-associated pathologies is not well understood. In this review we summarize the current knowledge concerning changes in vaginal microbiome and cervical disease. We discuss the potential functional interplay between specific bacterial groups and HPV infection outcomes.

scholarly journals Malignant Tumors of the Female Genital Tract – a Hospital Based Analysis

2016 ◽  
Vol 10 (2) ◽  
pp. 24-28
Author(s):  
R Joshi ◽  
G Baral ◽  
K Malla
Keyword(s):  
Ovarian Cancer ◽  
Cervical Cancer ◽  
Endometrial Cancer ◽  
Genital Tract ◽  
Malignant Tumors ◽  
Female Genital Tract ◽  
Limited Data ◽  
Corpus Uteri ◽  
Female Genital

Aims: The incidence of cancer and the cancer related deaths are increasing worldwide. There is limited data regarding  gynecological cancers in Nepal. This study is conducted to analyze the trends of female genital tract malignancies in Paropakar Maternity and Women’s Hospital (PMWH) and compare it with the national/international data.Methods: This was a retrospective study conducted in Department of Obstetrics/Gynecology and Pathology in PMWH.  All female diagnosed with the genital tract malignancies from July 2013 to July 2015 were included in the study.Results: Among 62 cases, cervical cancer was the commonest (71%) followed by ovarian cancer (14%), endometrial cancer (8%) and choriocarcinoma (3%). Majority of women belonged to 50-59 years for each type of tumors. Four-fifth of endometrial, half of the cervical and one-third of ovarian cancers were among grand-multipara. Sixty nine percent of women received treatment with 22 (9 cervical, 9 ovarian, 3 endometrial and one of corpus uteri)  surgical and 21 primary chemo/radiotherapy but 19 (31%) were lost for follow-up. Squamous type of cervical cancer was the commonest (93%).Conclusions: Cervical cancer was the commonest genital tract malignancy followed by ovarian cancer, endometrial cancer and choriocarcinoma. For each type of tumors, 50-59 years was the common age group and grand multiparity was seen in half of the women with the cervical cancer. Squamous type of cervical cancer was the commonest variety.  

scholarly journals Streptococcus agalactiae causing pyometra in an elderly female with cervical cancer

2012 ◽  
Vol 6 (12) ◽  
pp. 891-894 ◽  
Author(s):  
Ruchi Gupta ◽  
Anupam Das ◽  
Prakash S Krishna
Keyword(s):  
Cervical Cancer ◽  
Streptococcus Agalactiae ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Uterine Cavity ◽  
Elderly Female ◽  
Ascending Infection ◽  
Invasive Infections ◽  
Female Genital

Streptococcus agalactiae is an important cause of invasive infections in neonates and is emerging as an important pathogen in elderly females. S. agalactiae is a commensal organism of the female genital tract; however, isolation from the uterine cavity suggests ascending infection of this organism caused by occlusion of the uterine cavity. We report a case of S. agalactiae causing pyometra in an elderly female with cervical cancer.

scholarly journals Malignancies of the female genital tract from general gynecological services: Five years review at BPKIHS

1970 ◽  
Vol 2 (1) ◽  
pp. 35-38
Author(s):  
Hanoon P Pokharel ◽  
Nibedita Basnet ◽  
Dhruba Uprety ◽  
Basudeb Bannerjee ◽  
Aravind Sinha ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Genital Tract ◽  
Screening Program ◽  
Female Genital Tract ◽  
Carcinoma Cervix ◽  
Cancer Screening Program ◽  
Cervical Cancer Screening Program ◽  
Regional Community ◽  
Optimum Management ◽  
Female Genital

Aim: To observe the trend of malignant diseases of the female genital tract, and to assess pattern amongst the diagnosed cases and its management at BPKIHS. Methods: All the diagnosed cases of female genital malignancies were followed. Cases in advance stages were referred to Oncology Centers. Some patients opted to undergo treatment at BPKIHS. Those case sheets and histopathology reports were analyzed to see the trend and pattern of diseases and its optimum management. Referred cases who came for further follow up in the general gynecology department after consultation and treatment are also included in the study. Setting: Department of obstetrics & Gynecology and Pathology, BPKIHS. Results: Cervical cancer was the commonest malignant disease 216 (67.3%) followed by the ovary (17%), endometrium (10%), choriocarcinoma (3.4%) and vulva and vagina (2.8%). The mean (years in) age of the patients varied with the type of cancer as follows - cervix (30.9), ovary (40.4), endometrium (54.8), choriocarcinoma (25.6) and Vagina & vulva (42.2). Out of the total 216 patients Carcinoma Cervix only 20 patients were admitted for Radical surgery and treatment. 196 patients belonged to the group of advanced carcinoma cervix and were referred to the cancer hospital for radiotherapy and chemotherapy. Conclusion: Cancer cervix is the most common and manageable disease if diagnosed early provided mandatory selective screening program are implemented. The missed opportunity to diagnose the disease in time should be utilized by creating national or regional community - based cervical cancer screening program. General gynecological service provider can also contribute a lot to reduce the burden of disease. Keywords: Female genital malignancies, carcinoma cervix, radiotherapy and chemotherapy.   doi:10.3126/njog.v2i1.1474 N. J. Obstet. Gynaecol Vol. 2, No. 1, p. 35 - 38 May -June 2007

scholarly journals Risk of cervical cancer in women with a family history of breast and female genital tract neoplasms

2005 ◽  
Vol 117 (5) ◽  
pp. 880-881 ◽  
Author(s):  
Eva Negri ◽  
Carlo La Vecchia ◽  
Cristina Bosetti ◽  
Silvia Franceschi ◽  
Fabio Parazzini
Keyword(s):  
Cervical Cancer ◽  
Family History ◽  
Genital Tract ◽  
Female Genital Tract ◽  
History Of ◽  
Female Genital

scholarly journals Torsion of intestinal parasitic myoma after laparoscopic morcellation: a case report

2020 ◽  
Vol 2020 (3) ◽  
Author(s):  
Sofoudis Chrisostomos ◽  
Trouvas Dimitrios ◽  
Zioris Konstantinos
Keyword(s):  
Case Report ◽  
Clinical Significance ◽  
Broad Spectrum ◽  
Genital Tract ◽  
Benign Tumor ◽  
Female Genital Tract ◽  
Uterine Fibroids ◽  
Common Type ◽  
Rare Entity ◽  
Female Genital

Abstract Uterine fibroids represent the most common type of benign tumor of female genital tract with rate of incidence between 20% and 30% in women older than 35 years. According to current bibliography, the percentage is still increasing due to the fact that many women are postponing their reproductive mapping. Laparoscopic morcellation of uterine fibroids and uterus specimen after hysterectomies has great clinical significance, concerning dissemination and implantation of uterine fragments inside the peritoneal cavity. Parasitic myomas reveal a rare entity, reflecting a broad spectrum of pathogenesis. In cases of parasitic uterine fibroids surgical dissection is mandatory to avoid signs of malignancy.

scholarly journals Clinico-pathological characteristics of cervical cancer in Ghanaian women

2015 ◽  
Vol 3 (3) ◽  
pp. 27-32
Author(s):  
EM Der ◽  
K Adu-Bonsaffoh ◽  
Y Tettey ◽  
RA Kwame-Aryee ◽  
JD Seffah ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Postmenopausal Women ◽  
Genital Tract ◽  
Female Genital Tract ◽  
The Elderly ◽  
Cervical Cancers ◽  
Pathological Characteristics ◽  
High Prevalence ◽  
Ghanaian Women ◽  
Female Genital

Cervical cancer is a major cause of cancer related mortality in the developing countries, although preventable. The aim of this study was to use a retrospective descriptive study to determine the prevalence and the clinico-pathological characteristics of cervical cancer among genital tract ma-lignancies. This study reviewed all histologically confirmed female genital tract malignancies for cervical cancers from January 2002 to December 2011. The clinico-pathological features of women with cervical cancer were analyzed using SPSS software (version 18). A total of 1011(70.8%) out of 1,427 female genital tract malignancies were cervical cancers. The average prevalence of cervical cancer was 71.0%. The mean age of women with cervical cancer was 57.8(SD=13.8) years. The youngest patient was 22 years. The commonest (76.9%) presentation was bleeding per vaginalm followed by fungating cervical masses (12.4%). Majority (88.9%) of the bleeding were unprovoked and in postmenopausal women (98.8%). The major types of cervical cancers were Squamous cell carcinoma (SCC) (90.1%) and adenocarcinoma (5.8%), both were common in the elderly. The com-mon histological subtypes of cervical cancers in the study were; keratinizing SCC (73.3%), non-keratinizing SCC (14.7%), endometroid adenocarcinoma (4.5%), adenosquamous carcinoma (2.6%) and basaloid SCC (1.4%). This study found high prevalence of cervical cancer among female geni-tal tract cancers in Accra Ghana. The women were relatively older and presented with advanced stage of the disease. SCC was the major histological type of cervical cancer.Keywords: Ghana, cervical cancer, postmenopausal, women, premalignant, genital tract

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