Knockdown of the Bcl-2 gene increases sensitivity to EGFR tyrosine kinase inhibitors in the H1975 lung cancer cell line harboring T790M mutation

International Journal of Oncology ◽

10.3892/ijo.2013.1895 ◽

2013 ◽

Vol 42 (6) ◽

pp. 2094-2102 ◽

Author(s):

MAN ZOU ◽

SHU XIA ◽

LIANG ZHUANG ◽

NA HAN ◽

QIAN CHU ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Cell Line ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Cancer Cell Line ◽

Lung Cancer Cell Line ◽

Lung Cancer Cell ◽

T790m Mutation ◽

Egfr Tyrosine Kinase Inhibitors

Download Full-text

173 Synergistic toxicity of tyrosine kinase inhibitors with Hsp90 inhibitor 17-AAG in lung cancer cell line

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(10)71878-4 ◽

2010 ◽

Vol 8 (7) ◽

pp. 59-60

Author(s):

V.L. Damaraju ◽

M. Wilson ◽

M. Kuzma ◽

D. Mowles ◽

C.E. Cass ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Cell Line ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Cancer Cell Line ◽

Hsp90 Inhibitor ◽

Lung Cancer Cell Line ◽

Lung Cancer Cell ◽

Synergistic Toxicity

Download Full-text

Effect of siRNAs targeting the EGFR T790M mutation in a non-small cell lung cancer cell line resistant to EGFR tyrosine kinase inhibitors and combination with various agents

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2012.12.070 ◽

2013 ◽

Vol 431 (3) ◽

pp. 623-629 ◽

Author(s):

Gang Chen ◽

Peter Kronenberger ◽

Erik Teugels ◽

Ijeoma Adaku Umelo ◽

Jacques De Grève

Keyword(s):

Lung Cancer ◽

Kinase Inhibitors ◽

Cancer Cell Line ◽

Lung Cancer Cell Line ◽

Lung Cancer Cell ◽

Small Cell Lung ◽

T790m Mutation ◽

Egfr Tyrosine Kinase Inhibitors ◽

Download Full-text

Effect of simvastatin on the resistance to EGFR tyrosine kinase inhibitors in a non-small cell lung cancer with the T790M mutation of EGFR

Experimental Cell Research ◽

10.1016/j.yexcr.2014.02.026 ◽

2014 ◽

Vol 323 (2) ◽

pp. 288-296 ◽

Author(s):

Ki-Eun Hwang ◽

Su-Jin Kwon ◽

Young-Suk Kim ◽

Do-Sim Park ◽

Byoung-Ryun Kim ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Tyrosine Kinase Inhibitors ◽

Cell Lung Cancer ◽

Kinase Inhibitors ◽

Small Cell Lung ◽

T790m Mutation ◽

Egfr Tyrosine Kinase Inhibitors

Download Full-text

Hsp90 inhibitor NVP-AUY922 enhances the radiation sensitivity of lung cancer cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors

Oncology Reports ◽

10.3892/or.2015.3735 ◽

2015 ◽

Vol 33 (3) ◽

pp. 1499-1504 ◽

Author(s):

SHINSUKE HASHIDA ◽

HIROMASA YAMAMOTO ◽

KAZUHIKO SHIEN ◽

TOMOAKI OHTSUKA ◽

KEN SUZAWA ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Radiation Sensitivity ◽

Hsp90 Inhibitor ◽

Lung Cancer Cell ◽

Egfr Tyrosine Kinase Inhibitors

Download Full-text

Pretreatment T790M mutation detection by ultrasensitive PCR assay as predictor of efficacy in non-small lung cancer (NSCLC) patients treated with 1st or 2nd generation EGFR tyrosine kinase inhibitors (TKIs)

Annals of Oncology ◽

10.1093/annonc/mdz073.008 ◽

2019 ◽

Vol 30 ◽

pp. ii9-ii10

Author(s):

O.J. Juan Vidal ◽

J. Simarro ◽

D. Lorente Estelles ◽

G. Pérez-Simó ◽

N. Mancheno ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Mutation Detection ◽

Pcr Assay ◽

T790m Mutation ◽

2Nd Generation ◽

Egfr Tyrosine Kinase Inhibitors ◽

Download Full-text

Influence of EGFR-activating mutations on sensitivity to tyrosine kinase inhibitors in a KRAS mutant non-small cell lung cancer cell line

PLoS ONE ◽

10.1371/journal.pone.0229712 ◽

2020 ◽

Vol 15 (3) ◽

pp. e0229712 ◽

Author(s):

Yoshinori Tsukumo ◽

Mikihiko Naito ◽

Takayoshi Suzuki

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Kinase Inhibitors ◽

Cancer Cell Line ◽

Lung Cancer Cell Line ◽

Lung Cancer Cell ◽

Small Cell Lung ◽

Activating Mutations

Download Full-text

Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Lung Cancer: Distinct Natural History of Patients with Tumors Harboring the T790M Mutation

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-10-2692 ◽

2010 ◽

Vol 17 (6) ◽

pp. 1616-1622 ◽

Author(s):

Geoffrey R. Oxnard ◽

Maria E. Arcila ◽

Camelia S. Sima ◽

Gregory J. Riely ◽

Juliann Chmielecki ◽

...

Keyword(s):

Lung Cancer ◽

Natural History ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

T790m Mutation ◽

Egfr Tyrosine Kinase Inhibitors ◽

Download Full-text

Abstract 4686: Intermittent exposure to EGFR tyrosine kinase inhibitors selects lessEGFRT790M mutant clones than continuous exposure in lung cancer cell lines

10.1158/1538-7445.am2016-4686 ◽

2016 ◽

Author(s):

Youngjoo Lee ◽

Kyoung-Yeon Kim

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Cancer Cell ◽

Kinase Inhibitors ◽

Continuous Exposure ◽

Lung Cancer Cell ◽

Intermittent Exposure ◽

Egfr Tyrosine Kinase Inhibitors

Download Full-text

Establishment of a lung cancer cell line A549 highly expressing DNA oxidative damage related repair gene hOGG1

Academic Journal of Second Military Medical University ◽

10.3724/sp.j.1008.2010.00725 ◽

2010 ◽

Vol 30 (7) ◽

pp. 725-730

Author(s):

Yu WANG ◽

Zhong-yi LU ◽

Feng XU ◽

Yu-xi ZHU

Keyword(s):

Lung Cancer ◽

Oxidative Damage ◽

Cell Line ◽

Cancer Cell ◽

Cancer Cell Line ◽

Lung Cancer Cell Line ◽

Lung Cancer Cell ◽

Repair Gene ◽

Dna Oxidative Damage

Download Full-text

Toxic effect of TiO2 nanoparticles against human lung cancer cell line A549

Academic Journal of Second Military Medical University ◽

10.3724/sp.j.1008.2011.01091 ◽

2011 ◽

Vol 31 (10) ◽

pp. 1091-1095

Author(s):

Xiao-lin LI ◽

Yan-fang ZHANG ◽

Kai TANG ◽

Ying TANG ◽

Ruo-bing JIN ◽

...

Keyword(s):

Lung Cancer ◽

Toxic Effect ◽

Cell Line ◽

Cancer Cell ◽

Cancer Cell Line ◽

Lung Cancer Cell Line ◽

Human Lung Cancer ◽

Lung Cancer Cell ◽

Human Lung Cancer Cell

Download Full-text