scholarly journals In vivo evaluation of tumour acidosis for assessing the early metabolic response and onset of resistance to dichloroacetate by using magnetic resonance pH imaging

2017 ◽  
Vol 51 (2) ◽  
pp. 498-506 ◽  
Author(s):  
Annasofia Anemone ◽  
Lorena Consolino ◽  
Laura Conti ◽  
Francesca Reineri ◽  
Federica Cavallo ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Metabolic Response ◽  
In Vivo Evaluation ◽  
Ph Imaging ◽  
Early Metabolic Response

scholarly journals In vivo evaluation of cortical thickness with magnetic resonance imaging in patients with bipolar disorder

2009 ◽  
Vol 2 (2) ◽  
Author(s):  
Thomas Martin Doring ◽  
Tadeu Takao Almodovar Kubo ◽  
Juliana Rodrigues Doring ◽  
Jiosef Fainberg ◽  
Mario Juruena ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Bipolar Disorder ◽  
Magnetic Resonance ◽  
Cortical Thickness ◽  
Resonance Imaging ◽  
In Vivo Evaluation

scholarly journals Measurement of the acute metabolic response to hypoxia in rat tumours in vivo using magnetic resonance spectroscopy and hyperpolarised pyruvate

2015 ◽  
Vol 116 (3) ◽  
pp. 392-399 ◽  
Author(s):  
Joanne E. Bluff ◽  
Steven Reynolds ◽  
Stephen Metcalf ◽  
Tooba Alizadeh ◽  
Samira M. Kazan ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Metabolic Response ◽  
Resonance Spectroscopy

scholarly journals In Vivo Evaluation of Fontan Pathway Flow Dynamics by Multidimensional Phase-Velocity Magnetic Resonance Imaging

Circulation ◽  
1998 ◽  
Vol 98 (25) ◽  
pp. 2873-2882 ◽  
Author(s):  
Eliezer Be’eri ◽  
Stephan E. Maier ◽  
Michael J. Landzberg ◽  
Taylor Chung ◽  
Tal Geva
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Phase Velocity ◽  
Flow Dynamics ◽  
Resonance Imaging ◽  
In Vivo Evaluation

IN VIVO EVALUATION OF HIP INSTABILITY USING THREE-DIMENSIONAL MAGNETIC RESONANCE IMAGING

2012 ◽  
Vol 45 ◽  
pp. S281
Author(s):  
Keisuke Akiyama ◽  
Takashi Sakai ◽  
Junichiro Koyanagi ◽  
Hideki Yoshikawa ◽  
Kazuomi Sugamoto
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Three Dimensional ◽  
Resonance Imaging ◽  
In Vivo Evaluation ◽  
Hip Instability

scholarly journals Simultaneous 31P- and 1H-Nuclear Magnetic Resonance Studies of Hypoxia and Ischemia in the Cat Brain

1987 ◽  
Vol 7 (5) ◽  
pp. 543-551 ◽  
Author(s):  
Laszlo Gyulai ◽  
Mitchell Schnall ◽  
Alan C. McLaughlin ◽  
John S. Leigh ◽  
Britton Chance
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Metabolic Response ◽  
Lactate Clearance ◽  
Lactate Oxidation ◽  
Bilateral Carotid ◽  
Delayed Recovery ◽  
Lactate Levels ◽  
Nuclear Magnetic

The objective of this study was to evaluate simultaneous 31P/1H nuclear magnetic resonance (NMR) spectroscopy as a technique for monitoring and correlating changes in brain energy metabolism during hypoxia and ischemia. Five cats were studied with a protocol that involved 20 min of hypoxia (Pao2 20 mm), 60 min of recovery, 10 min of hypoxia with relative ischemia (bilateral carotid occlusion, PaO2 20 mm), and 60 min of recovery. Bifrontal and biparietal electrocorticograms (ECoG) were monitored continuously during the entire protocol. The results demonstrate that the degree of metabolic response is different in individual cats, but a number of quantitative relationships between metabolic parameters are consistently observed for all cats. First, there is agreement between increases in lactate and changes in intracellular pH; the observed relationship corresponds to an in vivo cerebral buffer capacity of 29 μmol/g/pH unit. Second, the delayed recovery of PCr is due to the effect of metabolic acidosis on the creatine kinase equilibrium and not to a delayed recovery of the ATP/ADP ratio. Third, the observed rate of lactate clearance from the cell is zero-order ( k = 0.36 μmol/g/min) for lactate levels >5 μm/g and may be composed of both lactate efflux from the cell and lactate oxidation.

Sign in / Sign up

Export Citation Format

Share Document