scholarly journals 3-Chloro-2,5-dihydroxybenzyl alcohol activates human cervical carcinoma HeLa cell apoptosis by inducing DNA damage

2007 ◽  
Author(s):  
Yanjun Zhang ◽  
Eun-Young Ahn ◽  
Yahong Jiang ◽  
Dong-Kyoo Kim ◽  
Sung-Goo Kang ◽  
...  
Keyword(s):  
Dna Damage ◽  
Hela Cell ◽  
Cervical Carcinoma ◽  
Cell Apoptosis ◽  
Human Cervical Carcinoma

scholarly journals Quercetin and aconitine synergistically induces the human cervical carcinoma HeLa cell apoptosis via endoplasmic reticulum (ER) stress pathway

PLoS ONE ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. e0191062 ◽  
Author(s):  
Xiu-Mei Li ◽  
Jing Liu ◽  
Fang-Fang Pan ◽  
Dong-Dong Shi ◽  
Zhi-Guo Wen ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Hela Cell ◽  
Er Stress ◽  
Cervical Carcinoma ◽  
Cell Apoptosis ◽  
Human Cervical Carcinoma ◽  
Stress Pathway

Quantum dots (QDs) restrain human cervical carcinoma HeLa cell proliferation through inhibition of the ROCK-c-Myc signaling

2013 ◽  
Vol 5 (3) ◽  
pp. 590 ◽  
Author(s):  
Liqun Chen ◽  
Guangbo Qu ◽  
Changwen Zhang ◽  
Shuping Zhang ◽  
Jiuyang He ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Quantum Dots ◽  
Hela Cell ◽  
Cervical Carcinoma ◽  
Human Cervical Carcinoma

scholarly journals Synthesis of the 6-Substituted Imidazo[1,2-a]Pyridine-3-yl-2- Phosphonopropionic Acids as Potential Inhibitors of Rab Geranylgeranyl Transferase

2021 ◽  
Vol 8 ◽  
Author(s):  
Damian Kusy ◽  
Aleksandra Marchwicka ◽  
Joanna Małolepsza ◽  
Katarzyna Justyna ◽  
Edyta Gendaszewska-Darmach ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Hela Cell ◽  
Cell Line ◽  
Cervical Carcinoma ◽  
Pyridine Ring ◽  
Hela Cell Line ◽  
Human Cervical Carcinoma ◽  
Geranylgeranyl Transferase ◽  
Potential Inhibitors ◽  
Inactive Analog

Twelve phosphonopropionates derived from 2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic acid (3-IPEHPC) were synthesized and evaluated for their activity as inhibitors of protein geranylgeranylation. The nature of the substituent in the C6 position of imidazo[1,2-a]pyridine ring was responsible for the compound's activity against Rab geranylgeranyl transferase (RGGT). The most active inhibitors disrupted Rab11A prenylation in the human cervical carcinoma HeLa cell line. The esterification of carboxylic acid in the phosphonopropionate moiety turned the inhibitor into an inactive analog.

Taxol-induced alteration of intracellular amino-acid profile related to human cervical carcinoma HeLa cell death

2011 ◽  
Vol 34 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Xiao-Fei Han ◽  
Yan-Qiu Liu ◽  
Long-Xing Wang ◽  
Qian-Xu Yang ◽  
Hong-Bin Xiao
Keyword(s):  
Cell Death ◽  
Amino Acid ◽  
Hela Cell ◽  
Cervical Carcinoma ◽  
Amino Acid Profile ◽  
Human Cervical Carcinoma ◽  
Intracellular Amino Acid
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