PROTEASES ASSOCIATED WITH GYNECOLOGICAL TUMORS

Author(s):  
C RUPPERT ◽  
S EHRENFORTH ◽  
B TUTSCHEK ◽  
A VERING ◽  
MW BECKMANN ◽  
...  
Keyword(s):  
Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1661
Author(s):  
Krzysztof Książek

Ovarian cancer (OC) is one of the most frequent malignancies of the female genital tract, and is still the leading cause of death from gynecological tumors [...]


ChemInform ◽  
2012 ◽  
Vol 43 (9) ◽  
pp. no-no
Author(s):  
Anna Torres ◽  
Kamil Torres ◽  
Ryszard Maciejewski ◽  
William H. Harvey
Keyword(s):  

Pharmacology ◽  
2017 ◽  
Vol 100 (5-6) ◽  
pp. 246-252 ◽  
Author(s):  
Haiping Liu ◽  
Jianye Wang ◽  
Lianbing Sheng ◽  
Yan Zhang ◽  
Ning Tang ◽  
...  

Uterine leiomyomas are common clinical gynecological tumors, which are a major health concern for many women. In the current study, we aimed to investigate the effect of paclitaxel (PTX) on uterine leiomyomas. A mouse model of uterine leiomyomas was established by estradiol benzoate, followed by treatment with increasing doses of PTX. PTX showed no dose-limiting toxicity that affected the survival of mice, and was able to restore the apoptosis level of uterus tissues of the model mice to normal levels. In this study, we discovered that PTX played a critical role in promoting apoptosis in the mouse model of uterine leiomyomas, which provides a new insight into the therapy of uterine leiomyomas.


1979 ◽  
Vol 8 (2) ◽  
pp. 226-233 ◽  
Author(s):  
Roland Hähnel ◽  
John D. Martin ◽  
Anne M. Masters ◽  
Thomas Ratajczak ◽  
Ella Twaddle

2016 ◽  
Vol 5 (1) ◽  
pp. 138-142 ◽  
Author(s):  
MASAKO ISHIKAWA ◽  
KENTARO NAKAYAMA ◽  
TOMOKA ISHIBASHI ◽  
EMI SATO ◽  
KOHEI NAKAMURA ◽  
...  

Author(s):  
N. Mimoune ◽  
◽  
M.Y. Azzouz ◽  
O. Benadjel ◽  
D. Khelef ◽  
...  

Among gynecological tumors, malignant uterine tumor (MUT) is the 6th most common cancer in women and the 15th most common cancer overall. There were approximately 382 069 new cases and 89 929 deaths attributed to this type worldwide in 2018. Therefore, MUT was the second most common gynecological cancer and the fourth leading cause of death due to gynecological cancer in 2018, and is expected to increase the incidence rate by more than 50% globally by 2040. Mortality rates are lowest in Central and South Asia and most of Africa. Survivors of MUT may experience treatment-related issues, including infertility, early onset of menopause, sexual problems, and lower limb lymphedema. Wbuilds its own database from national modeling incidence estimates, using incidence ratios with a sampling method that relies on the calculation of a weighted or simple average of the most popular local rates applied to the population of a few regions or by an approximate estimate based on data provided by health establishments in neighboring countries. While in Algeria, existing statistical and epidemiological data and updated information on the pathology are insuffi cient. The objective of this work is to highlight the importance and the situation of the MUT in this country and to describe the different recent aspects (etiology, diagnostics and treatment) related to the disease.


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