scholarly journals A comparative analysis of in vitro expansion of natural killer cells of a patient with autoimmune haemolytic anaemia and ovarian cancer with patients with other solid tumours

2011 ◽  
Vol 3 (2) ◽  
pp. 435-440 ◽  
Author(s):  
VIDYASAGAR DEVAPRASAD DEDEEPIYA ◽  
HIROSHI TERUNUMA ◽  
XUEWEN DENG ◽  
SUBRAMANI BASKAR ◽  
SADANANDA RAO MANJUNATH ◽  
...  
2001 ◽  
Vol 62 (10) ◽  
pp. 1092-1098 ◽  
Author(s):  
Stefan Carlens ◽  
Mari Gilljam ◽  
Benedict J Chambers ◽  
Johan Aschan ◽  
Hayrettin Guven ◽  
...  

2016 ◽  
Vol 62 (suppl 1) ◽  
pp. 23-24
Author(s):  
Lúcia Silla

SUMMARY The allogeneic hematopoietic stem cell transplantation (HSCT) can cure intermediate and high-risk acute myeloid leukemia. Even with the development of strategies to reduce HSCT toxicity, this is still a complex treatment with high morbidity and mortality. Knowledge of the graft versus leukemia effect of HSCT has prepared the way for the development of Adoptive Immunotherapy or in vitro expansion of activated lymphocytes without alloreactivity, with subsequent intravenous infusion. The infusion of genetically modified T lymphocytes and haploidentical natural killer cells has been tested as an alternative to HSCT with very interesting results worldwide and in Brazil, as we not only have the technology of in vitro expansion of clinical grade lymphocytes available, but also do it according to the Good Manufacturing Practices that have been determined internationally.


Author(s):  
Patrick Ming-Kuen Tang ◽  
Philip Chiu-Tsun Tang ◽  
Jeff Yat-Fai Chung ◽  
Jessica Shuk Chun Hung ◽  
Qing-Ming Wang ◽  
...  

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