scholarly journals [Corrigendum] Silencing of type Iγ phosphatidylinositol phosphate kinase suppresses ovarian cancer cell proliferation, migration and invasion

2021 ◽  
Vol 45 (4) ◽  
Author(s):  
Siyu Cao ◽  
Chunhua Chen ◽  
Junli Xue ◽  
Yan Huang ◽  
Xiaofeng Yang ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cell Proliferation ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Proliferation ◽  
Phosphatidylinositol Phosphate ◽  
Phosphatidylinositol Phosphate Kinase

scholarly journals Silencing of type Iγ phosphatidylinositol phosphate kinase suppresses ovarian cancer cell proliferation, migration and invasion

2017 ◽  
Vol 38 (1) ◽  
pp. 253-262 ◽  
Author(s):  
Siyu Cao ◽  
Chunhua Chen ◽  
Junli Xue ◽  
Yan Huang ◽  
Xiaofeng Yang ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cell Proliferation ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Proliferation ◽  
Phosphatidylinositol Phosphate ◽  
Phosphatidylinositol Phosphate Kinase

scholarly journals p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

2010 ◽  
Vol 107 (43) ◽  
pp. 18622-18627 ◽  
Author(s):  
M. K. Y. Siu ◽  
H. Y. Chan ◽  
D. S. H. Kong ◽  
E. S. Y. Wong ◽  
O. G. W. Wong ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cell Proliferation ◽  
Cancer Cell ◽  
Poor Prognosis ◽  
Ovarian Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Proliferation ◽  
P21 Activated Kinase

scholarly journals Silencing the Double-Stranded RNA Binding Protein DGCR8 Inhibits Ovarian Cancer Cell Proliferation, Migration, and Invasion

2013 ◽  
Vol 32 (3) ◽  
pp. 769-778 ◽  
Author(s):  
Yuqi Guo ◽  
Peng Tian ◽  
Chuanhe Yang ◽  
Zhibing Liang ◽  
Min Li ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cell Proliferation ◽  
Cancer Cell ◽  
Rna Binding ◽  
Ovarian Cancer Cell ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Migration And Invasion ◽  
Cancer Cell Proliferation ◽  
Double Stranded Rna

scholarly journals miR‑26a inhibits ovarian cancer cell proliferation, migration and invasion by targeting TCF12

2019 ◽  
Author(s):  
Sainan Gao ◽  
Tingting Bian ◽  
Min Su ◽  
Yifei Liu ◽  
Yuquan Zhang
Keyword(s):  
Ovarian Cancer ◽  
Cell Proliferation ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Proliferation

scholarly journals Cinobufotalin as a Novel Agent to Inhibit <i>in Vitro</i> Epithelial Ovarian Cancer Cell Proliferation, Migration and Invasion

2016 ◽  
Vol 06 (06) ◽  
pp. 343-351 ◽  
Author(s):  
Anthony McDowell ◽  
Syeda H. Afroze ◽  
Richard Tobin ◽  
Timothy C. McCormick ◽  
Martha Karen Newell-Rogers ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cell Proliferation ◽  
Epithelial Ovarian Cancer ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Proliferation ◽  
Epithelial Ovarian Cancer Cell ◽  
Novel Agent

scholarly journals S100A10 silencing suppresses proliferation, migration and invasion of ovarian cancer cells and enhances sensitivity to carboplatin

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Lingzhi Wang ◽  
Wei Yan ◽  
Xukun Li ◽  
Zhihua Liu ◽  
Tian Tian ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cell Proliferation ◽  
Cell Migration ◽  
Cancer Cell ◽  
Colony Formation ◽  
Ovarian Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Proliferation

Abstract Background Ovarian cancer is the leading cause of gynecological cancer-related mortality. The novel oncogene S100A10 has been reported to be involved in cancer cell proliferation, invasion and metastasis. The role of S100A10 in ovarian cancer has not been well studied and the effect of S100A10 on chemotherapy remains unclear. The aims of the present study were to investigate the functional role of S100A10 in the progression and carboplatin sensitivity of ovarian cancer. Methods We examined the expression levels in tissues of S100A10 in 138 cases of ovarian cancer by IHC. To determine the functional roles of downregulated S100A10 in ovarian cancer, cell proliferation, colony formation, cell migration and invasion assays were performed. Chemoresistance was analyzed by apoptosis assay. A xenograft tumor model was established to confirm the role of S100A10 in carboplatin resistance in vivo. Using Western blot assays, we also explored the possible mechanisms of S100A10 in ovarian cancer. Results The results showed that increased expression of S100A10 was positively associated with carboplatin resistance (P < 0.001), tumor grade (P = 0.048) and a poorer prognosis (P = 0.0053). Functional analyses demonstrated that S100A10 suppression significantly suppressed ovarian cancer cell proliferation, colony formation, cell migration and invasion, remarkably increased carboplatin-induced apoptosis in SKOV3 and A2780 cells and inhibited tumor growth in vivo. Downregulation of S100A10 expression could inhibit cell proliferation and enhance ovarian cancer cell sensitivity to carboplatin, possibly involving the regulation of cleaved-Caspase3 and cleaved-PARP. Conclusions Together, the results of the present study reveal that S100A10 expression can be used as a predictive marker for the prognosis of ovarian cancer and chemosensitivity to carboplatin.

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