Magnetic Resonance Imaging of Axial and Peripheral Disease in Psoriatic Arthritis: A Report From the 2020 GRAPPA Annual Meeting

2021 ◽  
pp. jrheum.201676
Author(s):  
Walter P. Maksymowych ◽  
Mikkel Østergaard
Keyword(s):  
Magnetic Resonance Imaging ◽  
Clinical Trials ◽  
Psoriatic Arthritis ◽  
Magnetic Resonance ◽  
Imaging Modality ◽  
Scoring Systems ◽  
Resonance Imaging ◽  
Structural Abnormalities ◽  
The Status ◽  
Magnetic Resonance Imaging Mri

Psoriatic arthritis (PsA) presents with diverse features of musculoskeletal inflammation that affect both axial and peripheral joints as well as entheses, tenosynovium, and bursae. Magnetic resonance imaging (MRI) is the imaging modality that is uniquely capable of identifying pathology in all these structures. The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) Magnetic Resonance Imaging Working Group has increasingly explored diverse MRI methodologies for the purposes of quantifying inflammatory and structural abnormalities in clinical trials and research. The 2020 GRAPPA virtual workshop presented an opportunity to review progress in the field, summarize the status of MRI scoring systems developed for PsA, and review representative patient cases.

scholarly journals Occlusal stabilization appliance: evaluation of its efficacy in the treatment of temporomandibular disorders

2004 ◽  
Vol 12 (3) ◽  
pp. 238-243 ◽  
Author(s):  
Elisa Emi Tanaka ◽  
Emiko Saito Arita ◽  
Bunji Shibayama
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Temporomandibular Joint ◽  
Temporomandibular Disorders ◽  
Imaging Modality ◽  
Clinical Status ◽  
Signs And Symptoms ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Evaluation

Occlusal stabilization appliances or splints are the most widely employed method for treatment of temporomandibular disorders (TMD). Magnetic Resonance Imaging (MRI) is the most indicated imaging modality to evaluate the components of the temporomandibular joint (TMJ). Forty patients with signs and symptoms of temporomandibular disorders were treated with splints for a mean period of 12 months, comprising regular semimonthly follow-ups. After stabilization of the clinical status, occlusal adjustments and MRI evaluation were performed. It was concluded that the success of this kind of treatment are related to the total (70%) or partial improvement (22.5%) of painful symptomatology and to the functional reestablishment of the craniomandibular complex. The MRI allowed evaluation and also the conclusion that the splints provide conditions for the organism to develop means to resist to the temporomandibular disorders by means of elimination of several etiologic factors. Moreover, after treatment the patients are able to cope with disc displacements with larger or smaller tolerance.

scholarly journals Magnetic Resonance Imaging in Psoriatic Arthritis — Update on Current Status and Future Perspectives: A Report from the GRAPPA 2010 Annual Meeting

2012 ◽  
Vol 39 (2) ◽  
pp. 408-412 ◽  
Author(s):  
MIKKEL ØSTERGAARD ◽  
RENÉ PANDURO POGGENBORG
Keyword(s):  
Magnetic Resonance Imaging ◽  
Psoriatic Arthritis ◽  
Magnetic Resonance ◽  
Annual Meeting ◽  
Current Status ◽  
Future Research ◽  
Future Perspectives ◽  
Resonance Imaging ◽  
Primary Driver ◽  
Magnetic Resonance Imaging Mri

The potential of magnetic resonance imaging (MRI) for use in clinical practice and research has gained increasing interest over the last decade. International collaborative initiatives from GRAPPA (Group for Research and Assessment of Psoriasis and Psoriatic Arthritis) and/or OMERACT (Outcome Measures in Rheumatology) may contribute to facilitating research, identifying appropriate areas for use, and reaching consensus on the optimal examination technique. Accordingly, GRAPPA, a primary driver of international research in psoriasis and psoriatic arthritis (PsA), has focused on the current use and future development of MRI and other modern imaging modalities in PsA. This review, presented at the GRAPPA 2010 annual meeting, describes the current status of MRI in PsA, with a focus on its use in diagnosis, monitoring, and prediction of the disease course and treatment response. Important areas for future research are also outlined.

scholarly journals Using magnetic resonance imaging in animal models to guide drug development in multiple sclerosis

2013 ◽  
Vol 20 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Nabeela Nathoo ◽  
V Wee Yong ◽  
Jeff F Dunn
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Clinical Trials ◽  
Magnetic Resonance ◽  
Animal Models ◽  
Mr Imaging ◽  
Preclinical Studies ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri ◽  
Potential Therapeutics

Major advances are taking place in the development of therapeutics for multiple sclerosis (MS), with a move past traditional immunomodulatory/immunosuppressive therapies toward medications aimed at promoting remyelination or neuroprotection. With an increase in diversity of MS therapies comes the need to assess the effectiveness of such therapies. Magnetic resonance imaging (MRI) is one of the main tools used to evaluate the effectiveness of MS therapeutics in clinical trials. As all new therapeutics for MS are tested in animal models first, it is logical that MRI be incorporated into preclinical studies assessing therapeutics. Here, we review key papers showing how MR imaging has been combined with a range of animal models to evaluate potential therapeutics for MS. We also advise on how to maximize the potential for incorporating MRI into preclinical studies evaluating possible therapeutics for MS, which should improve the likelihood of discovering new medications for the condition.

Comparison of spinal magnetic resonance imaging and myelography in cancer patients.

1987 ◽  
Vol 5 (10) ◽  
pp. 1663-1669 ◽  
Author(s):  
C Hagenau ◽  
W Grosh ◽  
M Currie ◽  
R G Wiley
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cancer Patients ◽  
Imaging Modality ◽  
Radicular Pain ◽  
Surface Coil ◽  
Resonance Imaging ◽  
Spinal Magnetic Resonance Imaging ◽  
Clinically Significant ◽  
Magnetic Resonance Imaging Mri

Spinal involvement by systemic malignancy is common, and often leads to extradural compression of the spinal cord and/or nerve roots by metastases. Rapid, anatomically accurate diagnosis is essential to the successful management of these patients. We compared spinal magnetic resonance imaging (MRI) with conventional myelography in a series of 31 cancer patients being evaluated for myelopathy (N = 10), or back/radicular pain (N = 21). All patients were evaluated between April 1985 and July 1986, and underwent both studies within ten days of each other (median, two days). MRI was performed on a 0.5 Tesla Technicare unit with a body surface coil, and results compared with standard contrast myelography. All studies were reviewed separately and in a "blinded" fashion. MRI and myelography were comparable in detecting large lesions that produced complete subarachnoid block (five of ten patients with myelopathy, three of twenty-one patients with back/radicular pain). In 19 of 31 patients, smaller but clinically significant extradural lesions were found. In nine of 19 cases, these lesions were demonstrated equally well by both modalities; in nine of 19 cases, these lesions were demonstrated by myelography alone; in one of 19, a lesion was demonstrated by MRI alone. Given our current technology, myelography appeared superior to MRI as a single imaging modality. However, MRI may be an alternative in patients where total myelography is technically impossible or unusually hazardous.

scholarly journals Sensitivity of Magnetic Resonance Imaging in the Detection of Colorectal Liver Metastases

2008 ◽  
Vol 90 (1) ◽  
pp. 25-28 ◽  
Author(s):  
S Blyth ◽  
A Blakeborough ◽  
M Peterson ◽  
IC Cameron ◽  
AW Majeed
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Imaging Modality ◽  
Invasive Technique ◽  
Resonance Imaging ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri ◽  
High Degree

INTRODUCTION The aim of this study was to evaluate the sensitivity of magnetic resonance imaging (MRI) in the detection of colorectal liver metastases. PATIENTS AND METHODS Pre-operative MRI scanning of the liver was performed by a single radiologist and the size and number of definite liver metastases were recorded. Patients then underwent hepatectomy with routine intra-operative ultrasonography (IOUS) and resected specimens were sent for histopathology. Pathology findings were compared with those of MRI scans to determine the sensitivity of this imaging modality. Exclusions were patients undergoing hepatic resection more than 4 weeks after the MRI scan, those undergoing chemotherapy at the time of the scan, and those with conglomerate unilobar metastases. RESULTS Complete data were available for 84 patients. There was total agreement between MRI, IOUS and histology in 79 patients (101 metastases). MRI missed 5 metastases in 5 patients that were found on IOUS (or palpation of superficial lesions) and subsequently confirmed by histological examination. These measured 5 mm or less (4 patients) and 7 mm (one patient). The sensitivity of MRI in the detection of colorectal liver metastases was thus 94% for all lesions and 100% for lesions 1 cm or larger in diameter. CONCLUSIONS MRI of the liver is a non-invasive technique with an extremely high degree of sensitivity in the detection of colorectal liver metastases and should be considered as the ‘gold standard’ in the pre-operative imaging of these patients.

Nail Disease in Psoriatic Arthritis: Distal Phalangeal Bone Edema Detected by Magnetic Resonance Imaging Predicts Development of Onycholysis and Hyperkeratosis

2012 ◽  
Vol 39 (4) ◽  
pp. 841-843 ◽  
Author(s):  
NICOLA DALBETH ◽  
KAREN PUI ◽  
MARIA LOBO ◽  
ANTHONY DOYLE ◽  
PETER B. JONES ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Psoriatic Arthritis ◽  
Magnetic Resonance ◽  
Bone Erosion ◽  
Resonance Imaging ◽  
Mri Features ◽  
Bone Edema ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri ◽  
Nail Disease

Objective.To examine the association between magnetic resonance imaging (MRI) features of distal phalanx (DP) disease and the progression of nail pathology in psoriatic arthritis (PsA).Methods.Clinical nail assessment and hand MRI scans were done on 34 patients with PsA. Twenty patients had repeat nail assessments after 1 year.Results.Nails with onycholysis and hyperkeratosis at baseline were more likely to have corresponding DP bone erosion and proliferation on MRI. DP bone edema on baseline MRI was associated with development of onycholysis and hyperkeratosis in corresponding nails.Conclusion.Our data suggest that DP inflammation is central in the development of psoriatic nail disease.

scholarly journals Procedural Sedation of Preterm Neonate with Frequent Apnea during Magnetic Resonance Imaging: A Case Report

2021 ◽  
Vol 27 (2) ◽  
pp. 88-90
Author(s):  
Jaewoong Jung ◽  
Juhui Park ◽  
Yang Hoon Chung ◽  
Won Seok Chae
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Preterm Infants ◽  
Preterm Neonate ◽  
Imaging Modality ◽  
Resonance Imaging ◽  
Older Children ◽  
History Of ◽  
Magnetic Resonance Imaging Mri ◽  
Careful Assessment

Magnetic resonance imaging (MRI) is a useful and safe imaging modality for examining preterm infants. However, MRI examination requires careful precautions, and infants and children are likely to require deep sedation or anesthesia to keep them still during the examination. Sedation has various risks and the greatest concern of sedation is cardiorespiratory events. In addition, delicate titration is also necessary for preterm infants because propofol pharmacokinetics is different from those in older children. We successfully completed sedation of a preterm neonate (gestational age, 32+1 weeks; birth weight, 1,970 g) with a history of frequent apnea through careful assessment and continuous monitoring. We want to suggest alternative options for airway management of the high risk of respiratory complications.

scholarly journals Recent Advances in Lanthanide Based Nano-Architectures as Probes for Ultra High-Field Magnetic Resonance Imaging

2020 ◽  
Vol 27 (3) ◽  
pp. 352-361 ◽  
Author(s):  
Silvanose Biju ◽  
Tatjana N. Parac-Vogt
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Field ◽  
Imaging Modality ◽  
Short Review ◽  
Mri Contrast Agents ◽  
Lanthanide Ions ◽  
Resonance Imaging ◽  
Multiple Imaging ◽  
Magnetic Resonance Imaging Mri

Paramagnetic Lanthanide ions incorporated into nano- architectures are emerging as a versatile platform for Magnetic Resonance Imaging (MRI) contrast agents due to their strong contrast enhancement effects combined with the platform capability to include multiple imaging modalities. This short review examines the application of lanthanide based nanoarchitectures (nanoparticles and nano- assemblies) in the development of multifunctional probes for single and multimodal imaging involving high field MRI as one imaging modality.

Magnetic Resonance Imaging of Vascular Lesions in Children

1984 ◽  
Vol 25 (6) ◽  
pp. 449-456 ◽  
Author(s):  
H. G. Ringertz ◽  
R. C. Brasch ◽  
A. Brody ◽  
R. Ehman ◽  
C. A. Gooding
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Vascular Lesions ◽  
Vascular Tumors ◽  
Resonance Imaging ◽  
Vascular Abnormalities ◽  
Non Invasive ◽  
Internal Structures ◽  
The Status ◽  
Magnetic Resonance Imaging Mri

Ten children aged 1 week to 13 years with 12 vascular abnormalities were examined with magnetic resonance imaging (MRI) and other imaging modalities. MRI was the only single non-invasive modality that demonstrated all lesions and their internal structures. The vascular nature of 3 hemangiomas could not be established with MRI alone. No marked differences in MRI appearance was seen in 5 cases with vascular tumors compared with 5 cases with other vascular abnormalities. The status of the blood in the vascular lesions as flowing fast, slow, or not at all was successfully assessed in 9 of the 12 lesions.

Magnetic Resonance Imaging in Psychiatry*

1987 ◽  
Vol 32 (8) ◽  
pp. 702-712 ◽  
Author(s):  
P. Conlon ◽  
M.R. Trimble
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Structural Information ◽  
Imaging Modality ◽  
Functional Change ◽  
Resonance Imaging ◽  
Basic Principles ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain ◽  
Radiological Technique

Magnetic resonance imaging (MRI) is a relatively new radiological technique that may be useful in the study of psychiatric illness. MRI gives detailed structural information about the brain and also allows quantification of functional change. Current areas of study relevant to psychiatry include: schizophrenia, dementia, epilepsy and, to a lesser extent, alcohol and affective disorders. The authors review the basic principles of MRI, discuss the recent application to psychiatry, indicate its potential advantages and comment on the current limitations of this imaging modality.

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