Otoprotective Effect of Nimesulide: Biochemical and Histopathologic Evaluation

2022 ◽  
Vol 18 (1) ◽  
pp. 44-52
Author(s):  
Ozan Kuduban ◽  
Zeynep Suleyman ◽  
Mine Gulaboglu ◽  
Gulce Naz Yazici ◽  
Halis Suleyman
Keyword(s):  
Histopathologic Evaluation

Histopathologic evaluation of the intraoperative specimens of the entire aorta

2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
A Juraszek ◽  
G Bayer ◽  
T Dziodzio ◽  
J Holfeld ◽  
J Dumfarth ◽  
...  
Keyword(s):  
Histopathologic Evaluation

Serum haptoglobin concentrations in feline inflammatory bowel disease and small-cell alimentary lymphoma: a potential biomarker for feline chronic enteropathies

2021 ◽  
pp. 1098612X2199144
Author(s):  
Edwina K Love ◽  
Nicole F Leibman ◽  
Randy Ringold ◽  
Kenneth Lamb
Keyword(s):  
Inflammatory Bowel Disease ◽  
Inflammatory Disease ◽  
Bowel Disease ◽  
Prognostic Significance ◽  
Small Cell ◽  
Clinically Normal ◽  
Serum Haptoglobin ◽  
Potential Biomarker ◽  
Histopathologic Evaluation ◽  
Inflammatory Bowel

Objectives The aim of this study was to evaluate serum haptoglobin as a biomarker to differentiate between small-cell alimentary lymphoma and inflammatory bowel disease in cats. Methods Client-owned domestic cats with and without chronic gastrointestinal signs were enrolled in the study. Serum was collected from each patient and serum haptoglobin levels were measured using ELISA. In cats with gastrointestinal signs, histopathologic evaluation of endoscopic biopsies harvested from the intestinal tract was used to separate them into inflammatory bowel disease and small-cell lymphoma cohorts. Serum haptoglobin levels were statistically analyzed and compared among the three groups: healthy cats; cats with inflammatory bowel disease; and cats with small-cell alimentary lymphoma. Results Sixty-two cats were enrolled in the study, including 20 clinically normal cats, 14 cats with small-cell alimentary lymphoma and 28 cats with inflammatory bowel disease. The mean ± SD serum haptoglobin was 73.2 ± 39.1 mg/dl in normal cats, 115.3 ± 72.8 mg/dl in cats with inflammatory bowel disease and 133.1 ± 86.1 mg/dl in cats with small-cell alimentary lymphoma. Cats with inflammatory bowel disease and lymphoma had significantly higher serum haptoglobin than controls, with P values of 0.0382 and 0.0138, respectively. There was no statistical difference between the inflammatory bowel disease and lymphoma cohorts ( P = 0.4235). For every one unit increase in serum haptoglobin, the odds of gastrointestinal inflammatory disease (inflammatory bowel disease or small-cell alimentary lymphoma) increased by 1.41% ( P = 0.0165). Conclusions and relevance Serum haptoglobin is a useful biomarker for distinguishing between normal cats and those with gastrointestinal inflammatory disease, but it could not significantly differentiate between inflammatory bowel disease and lymphoma. Additional studies may be beneficial in determining the prognostic significance of serum haptoglobin as it may relate to the severity of gastrointestinal inflammation.

scholarly journals Histopathologic Evaluation of COVID-19 Patients with Peripheral Arterial Thromboembolism: Does clot composition make any sense?

2021 ◽  
Author(s):  
Nihan Yesilkaya ◽  
Tahsin Murat Tellioglu ◽  
Fulya Cakalagaoglu Unay ◽  
Hasan İner ◽  
Yuksel Besir ◽  
...  
Keyword(s):  
Arterial Thromboembolism ◽  
Histopathologic Evaluation ◽  
Peripheral Arterial

Dietary behavior and achievement in Sprague Dawley rats treated with aluminum and histopathologic evaluation of the murine model treated with N-nitroso-N-methylurea (NMU) as inducing agent

2016 ◽  
Vol 259 ◽  
pp. S167-S168 ◽  
Author(s):  
A.M. García-Alegría ◽  
A. Gómez-Álvarez ◽  
I. Anduro-Corona ◽  
A. Burgos-Hernández ◽  
E. Ruiz-Bustos ◽  
...  
Keyword(s):  
Murine Model ◽  
Dietary Behavior ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Histopathologic Evaluation

Short- and long-term histopathologic evaluation of stenting using a self-expanding nitinol stent in pig carotid and iliac arteries

1999 ◽  
Vol 48 (3) ◽  
pp. 316-323 ◽  
Author(s):  
Stefan Verheye ◽  
Mahomed Y. Salame ◽  
Keith A. Robinson ◽  
Mark J. Post ◽  
Joseph P. Carrozza ◽  
...  
Keyword(s):  
Iliac Arteries ◽  
Nitinol Stent ◽  
Histopathologic Evaluation ◽  
Short And Long Term

scholarly journals Intralesional polysulphated glycosaminoglycan as treatment of equine collagenase induced tendinitis: clinical, ultrasonographic and histopathologic evaluation

2004 ◽  
Vol 56 (6) ◽  
pp. 701-708 ◽  
Author(s):  
S. Marxen ◽  
J.C. Lacerda Neto ◽  
J.C. Canola ◽  
J.R.E. Moraes ◽  
G. Ribeiro
Keyword(s):  
Intralesional Injection ◽  
Control Groups ◽  
Beneficial Effects ◽  
Thoracic Limb ◽  
Superficial Digital Flexor Tendon ◽  
Histopathologic Evaluation ◽  
Intralesional Injections ◽  
Males And Females ◽  
Histopathologic Analysis ◽  
And Control

The effect of intratendineous injections of polysulphated glycosaminoglycan (PSGAG) as treatment of collagenase-induced tendonitis was studied. Two groups (GI and GII) of five Arabian horses each, males and females, two to six year-old, were submitted to experimental tendinitis of the superficial digital flexor tendon of the left thoracic limb by intratendineous injection of 1.0ml of collagenase (2.5mg/ml). Seven days after the induced-lesions were created, the horses of GI received five intralesional injections of 1.0ml (125mg) of PSGAG, every four days. Horses of GII received injections of saline in the same dose and rate. Clinical and ultrasonographic evaluations were performed periodically, during 150 days. All animals showed lameness, increased local pain, heat and swelling 24 hours after the injury was created. All signs, except to swelling, which remained visible by the end of the study, showed regression in all animals. Lesions of variable size, shape and position were evidenced by the ultrasonographic evaluation, reaching maximum severity between the seventh and the 23rd days. By the end of the study, the echogenicity grade ranged from 1 to 2, and the grade of fiber alignment from 0 to 2. The histopathologic analysis demonstrated repair areas with intense fibroplasia and neovascularization, collagen fibers poorly organized, and thickened hypercellular endotenon. The data of this study did not show significant differences between the treated and control groups, therefore leading to the conclusion that the intralesional injection of PSGAG did not have beneficial effects in the treatment of collagenase-induced tendinitis.

scholarly journals A histopathologic evaluation of the plasma skin regeneration system (PSR) versus a standard carbon dioxide resurfacing laser in an animal model

2008 ◽  
Vol 40 (2) ◽  
pp. 93-99 ◽  
Author(s):  
R. Fitzpatrick ◽  
E. Bernstein ◽  
S. Iyer ◽  
D. Brown ◽  
P. Andrews ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Animal Model ◽  
Skin Regeneration ◽  
Regeneration System ◽  
Histopathologic Evaluation

scholarly journals ADENEXAL CYSTS

2011 ◽  
Vol 18 (01) ◽  
pp. 32-40
Author(s):  
TEHREEN RIAZ ◽  
SARWAT JABEEN ◽  
WASEEM TALIB ◽  
Nabeela Shami
Keyword(s):  
Demographic Data ◽  
Lower Abdominal Pain ◽  
Abdominal Distension ◽  
Exploratory Laparotomy ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Ovarian Tumour ◽  
Risk Of Malignancy ◽  
Histopathologic Evaluation ◽  
Operative Findings

Objectives: (1) To evaluate the risk of malignancy in surgically removed ovarian cysts that was before the operation neither simple nor complex. (2) To determine the relationship of age with type of ovarian tumour. (3) To categorize the management of these cases according to the intra-operative findings. (4) To analyze the occurrence of various histopathological types of tumour. Date Source: Medline Study Design: Single centered prospective descriptive study of 150 cases. Place and Duration of Study: Department of Obstetrics and Gynaecology at Shaikh Zayed Hospital Lahore from 1st July 2005 to,31st December 2006. Subject and method: 150 patients presented with adnexal cysts on preoperative ultrasonography, peroperative findings and histopathology reports. These patients were followed up in OPD. Results: Showed the distribution of non-neoplastic and neoplastic tumours which were 84% and 16% respectively. The occurrence of malignancy increased with advancing age especially after 45 years Common presentations were lower abdominal pain (53%) followed by menstrual disturbances (30%), abdominopelvic mass, abdominal distension and infertility. Risk of malignancy also increased with parity. 73% masses were unilateral, 84% benign masses were unilocular whilst 85% malignant masses were echogenic and the complex cysts with papillary projection and multiloculations showed 3-6 times higher risk of malignancy. Most patients were managed by exploratory laparotomy. Cystectomy and total abdominal hysterectomy were the commonest procedures performed. Regarding histopathologic evaluation 40% patients had tumours, 2.66% borderline malignancy and 13.3% malignant. 44% had non-neoplastic lesions. Serous and endometriotic cysts were the commonest benign histopathologic types and among malignant ones, epithelial ovarian tumours were the leading variants. Conclusions: Preoperative characterization of adnexal masses using sonographic and demographic data may have considerable potential in determining risk of malignancy and may be advantageous in terms of counseling patients for management.

scholarly journals Dermatoscopy in the evaluation of cutaneous lesions in patients with familial atypical multiple-mole melanoma syndrome

2016 ◽  
Vol 85 (2) ◽  
pp. 41-43
Author(s):  
Robert Bobotsis ◽  
Brandon Chau
Keyword(s):  
Cancer Type ◽  
Clinical Tool ◽  
First Line ◽  
Cutaneous Lesions ◽  
North Americans ◽  
Skin Cancers ◽  
Histopathologic Evaluation ◽  
Asymmetric Shape ◽  
Atypical Nevi ◽  
Common Cancer Type

Skin cancer is currently the most common cancer type afflicting North Americans today and with an aging population the incidence is likely to increase. Certain skin cancers such as melanoma can result in significant morbidity and mortality especially if not identified and treated early. The traditional ABCDE rule (asymmetric shape, irregular borders, variation in colour, diameter >6 mm and evolution/elevation of the lesion) used to identify concerning tumours will in fact miss many early melanomas. This problem is exacerbated in patients with hereditary forms of melanoma such as Familial Atypical Multiple- Mole Melanoma (FAMMM) syndrome where multiple atypical nevi satisfying the ABCDE criteria are present and would therefore warrant biopsy. Most of these biopsies would be unnecessary and would increase the patient’s morbidity. Dermatoscopy is a clinical tool that provides a bridge between clinical and histopathologic evaluation and has proven to be helpful in triaging suspicious lesions in the general population and to be a first-line screening tool to increase the detection of early melanomas in patients with FAMMM.

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