Egg Injection of Ascorbic Acid Stimulates Leucocytosis and Cell Proliferation in the Bursa of Fabricius

2013 ◽  
Vol 12 (8) ◽  
pp. 464-472 ◽  
Author(s):  
Sarah Sgavioli ◽  
Liliana Longo Borges ◽  
Vitor Rosa de Almeida ◽  
Mariana Thimotheo ◽  
Joao Ademir de Oliveira ◽  
...  
1960 ◽  
Vol 20 (3) ◽  
pp. 251-255 ◽  
Author(s):  
M. PEREK ◽  
A. EILAT

SUMMARY Injections of both fast- and long-acting adrenocorticotrophic hormone (ACTH) were followed by depletion of adrenal ascorbic acid (AA) in 3-week- and 6-week-old chicks when the bursa of Fabricius had been removed. The speed of depletion was similar to that known in mammals. Intact birds did not respond in this respect to ACTH treatment. A marked involution of the bursa of Fabricius occurred in chicks treated with prolonged-acting ACTH. A depletion of the total AA content of the bursa was noted, without any significant change in its concentration in the tissue of the gland. The results of the experiments indicate that the bursa of Fabricius is involved in preventing the release of adrenal AA after ACTH treatment.


2015 ◽  
Vol 14 (7) ◽  
pp. 387-393 ◽  
Author(s):  
Dayane Lilian Pires Igle ◽  
Sarah Sgavioli ◽  
Euclides Braga Malh ◽  
Rodrigo Garofallo ◽  
Luiz Gustavo Rombola ◽  
...  

The Lancet ◽  
1972 ◽  
Vol 299 (7749) ◽  
pp. 542 ◽  
Author(s):  
Ewan Cameron ◽  
Douglas Rotman

2021 ◽  
Vol 144 ◽  
pp. 112306
Author(s):  
Yi-Jen Hsueh ◽  
Yaa-Jyuhn James Meir ◽  
Jui-Yang Lai ◽  
Chieh-Cheng Huang ◽  
Tsai-Te Lu ◽  
...  

2015 ◽  
Vol 63 (2) ◽  
pp. 161-168
Author(s):  
Jaqueline Aparecida FIUZA ◽  
Elizabeth Ferreira MARTINEZ ◽  
Rui Barbosa de BRITO JÚNIOR

OBJECTIVE: To evaluate the action of risedronate and cobalamin, and effects when associated, when administered osteoblastic cells. METHODS: The MC3T3 cells were cultivate in the media α-MEM and α-MEM supplemented with mineralizing factors, ascorbic acid and disodium α-glyicerophosphate, and treated with risedronate, cobalamin, and risedronate associated with cobalamin in a concentration of 10-3 M. The cell proliferation and formation of calcium and phosphate nodules were evaluated at 24 hours, 48 hours, 72 hours, 5 days and 7 days via a Neubauer Chamer count, Alizarin and the von Kossa reaction. RESULTS: The results showed that the growth curve for cell proliferation and the formation of mineral nodules was similar for both cultures analyzed. CONCLUSION: The conclusion was reached that using risedronate, cobalamin and both drugs in combination on osteoblastic cell cultures does not cause alterations to their growth or in the formation of calcium and phosphate nodules.


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