scholarly journals Fluid dynamics at a pinch ; droplet and bubble formation in microfluidic devices

2011 ◽  
Author(s):  
Wim Hoeve, van
Lab on a Chip ◽  
2015 ◽  
Vol 15 (9) ◽  
pp. 2140-2144 ◽  
Author(s):  
Tohid Pirbodaghi ◽  
Daniele Vigolo ◽  
Samin Akbari ◽  
Andrew deMello

To better understanding fluid dynamics within microfluidic channels, herein, we present an accurate experimental approach for studying the fluid dynamics of rapid processes within microfluidic devices using bright-field microscopy with white light illumination.


Author(s):  
D. Obiso ◽  
M. Reuter ◽  
A. Richter

AbstractThe hydrodynamics of a Top Submerged Lance (TSL) slag bath are investigated here by means of Computational Fluid Dynamics (CFD) simulation. The object of the study is the pilot-scale furnace located at TU Bergakademie Freiberg, where air is injected beneath the slag bath with a top lance. The fluid dynamics system is evaluated at operating conditions, with experimentally measured slag physical properties and real flow rates. The numerical approach is based on the Volume Of Fluid (VOF) model, a front-tracking method that allows the interface to be geometrically reconstructed. Using a fine computational grid, the multiphase interactions are calculated with a high level of detail, revealing the mechanisms of bubble formation and bath dynamics. Two lance configurations are compared, with and without a swirler, and the effect on the hydrodynamics is discussed with regards to key features of the process, such as bubble dynamics, slag splashing, the interface area, rotational sloshing, and bath mixing. The model predicts bubble frequencies in the range of 2.5 to 3 Hz and captures rotational sloshing waves with half the frequencies of the bubble detachment. These results agree with real furnace data from the literature, proving the reliability of the computing model and adding value to the empirical understanding of the process, thanks to the direct observation of the resolved multiphase flow features. The comparative study indicates that the air swirler has an overall positive effect in addition to the proposed enhancement of lance cooling, with an increase in the bath mixing and a reduction in the splashing.


Author(s):  
Chidambaram Narayanan ◽  
Djamel Lakehal

For the design and development of new microfluidic devices reliable modeling and simulation tools must be made available. Many extensions to conventional computational fluid dynamics are required, especially multiphase fluid dynamics simulation capability. A new dynamic contact angle model is presented here, which does not require the specification of a contact angle or contact-line velocity. The level-set method is used for interface capture. The model is tested for unit problems such as relaxation to equilibrium of a contact line. It is then applied to the problem of fluid filling in a prototypical microdevice to show its utility as a design tool.


Soft Matter ◽  
2018 ◽  
Vol 14 (43) ◽  
pp. 8780-8791
Author(s):  
Shuyi Wu ◽  
Chuang Li ◽  
Quanshui Zheng ◽  
Luping Xu

We simulated the thorough process of DNA fragmentation in microfluidics. The conformation of DNA preconditioned by shear flow and the strain rate of elongational flow are two critical parameters for DNA fragmentation.


2021 ◽  
Vol 22 (4) ◽  
pp. 2011
Author(s):  
Adelina-Gabriela Niculescu ◽  
Cristina Chircov ◽  
Alexandra Cătălina Bîrcă ◽  
Alexandru Mihai Grumezescu

Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods can be chosen to manufacture such platforms of desired size, shape, and geometry. Whether they are used alone or in combination with other devices, microfluidic chips can be employed in nanoparticle preparation, drug encapsulation, delivery, and targeting, cell analysis, diagnosis, and cell culture. This paper presents microfluidic technology in terms of the available platform materials and fabrication techniques, also focusing on the biomedical applications of these remarkable devices.


2008 ◽  
Vol 130 (9) ◽  
Author(s):  
Hussameddine S. Kabbani ◽  
Martin J. Mack ◽  
Sang W. Joo ◽  
Shizhi Qian

A new approximate solution for the velocity profile of steady incompressible magnetohydrodynamic (MHD) flows in a rectangular microchannel driven by the Lorentz force is proposed. Mean velocity and mass flow rate in a channel, subsequently derived, can be used efficiently for many MHD-based microfluidic applications, including the design of a MHD-based microfluidic network without resorting to costly full-scale computational fluid dynamics. The closed-form solutions, provided for both direct-current (dc) and alternating-current (ac) electric and magnetic fields, are in simple forms, without any series or functions to evaluate, and so can be readily used for inverse or control problems associated with MHD-based lab-on-a-chip (LOC) devices. Extensive comparisons with previous analytical, computational, and experimental results are performed, and summarized in the present study. The proposed solutions are shown to agree better with existing experimental and computational reports than previous approximations and are to be used in a broad range of MHD-based LOC applications with both dc and ac fields with required accuracy.


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