Non-Invasive Cuffless Blood Pressure Monitoring System

Author(s):  
Harinderjit Singh ◽  
Dilip Kumar

These days most of the Blood Pressure (BP) measuring devices are having inflatable cuff that is needed to be occluded on the patient's arm for measuring blood pressure. This technique is not suitable in cases where continuous measurement of BP is required. Therefore, this work is aimed at designing of non-invasive and continuously monitors the blood pressure by using Pulse Transit Time (PTT) technique. For taking out PTT both of the signals are extracted from the body of the patient with the help of bio sensors i.e. Electrocardiogram (ECG) sensor and Photoplethysmogram (PPG) sensor. PTT was measured by taking the peak to peak time difference of ECG signal and PPG signal and this PTT is indirectly correlated with blood pressure, based on which Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) is calculated.

2020 ◽  
Author(s):  
Michael McGillion ◽  
Nazari Dvirnik ◽  
Stephen Yang ◽  
Emilie Belley-Côté ◽  
Andre Lamy ◽  
...  

BACKGROUND Background: Continuous hemodynamic monitoring is the standard of care for patients intraoperatively, but vital signs monitoring is performed only periodically on post-surgical wards, and patients are routinely discharged home with no surveillance. Wearable continuous monitoring biosensor technologies have the potential to transform postoperative care with early detection of impending clinical deterioration. OBJECTIVE Objective: Our aim was to validate the accuracy of the Cloud DX Vitaliti™ Continuous Vital Signs Monitor (CVSM) continuous non-invasive blood pressure measurements in post-surgical patients. Usability of the Vitaliti™ CVSM was also examined. METHODS Methods: Included patients were recovering from surgery in a cardiac intensive care unit. Validation procedures were according to AAMI - ISO 81060-2 2013 standards for Wearable, Cuffless Blood Pressure Measuring Devices. In static (seated in bed) and supine positons, three 30-second cNIBP measurements were taken for each patient with the Vitaliti™ CVSM and an invasive arterial catheter. The errors of these determinations were calculated. Participants were interviewed about device acceptability RESULTS Results: Data for 21 patients were included in the validation analysis. The overall mean and SD of the errors of determination for the static position were -0.784 mmHg (SD 4.594) for systolic blood pressure and 0.477 mmHg (SD 1.668) for diastolic blood pressure. Errors of determination were slightly higher for the supine position at 3.533 mmHg (SD 6.335) for systolic blood pressure and 3.050 mmHg (SD 3.619) for diastolic blood pressure. The majority rated the Vitaliti™ CVSM as comfortable. CONCLUSIONS Conclusion: The Vitaliti™ CVSM was compliant with AAMI-ISO 81060-2:2013 standards and well-received by patients. CLINICALTRIAL Trial Registration: ClinicalTrials.gov (NCT03493867)


2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Elisa Mejía-Mejía ◽  
James M. May ◽  
Mohamed Elgendi ◽  
Panayiotis A. Kyriacou

AbstractHeart rate variability (HRV) utilizes the electrocardiogram (ECG) and has been widely studied as a non-invasive indicator of cardiac autonomic activity. Pulse rate variability (PRV) utilizes photoplethysmography (PPG) and recently has been used as a surrogate for HRV. Several studies have found that PRV is not entirely valid as an estimation of HRV and that several physiological factors, including the pulse transit time (PTT) and blood pressure (BP) changes, may affect PRV differently than HRV. This study aimed to assess the relationship between PRV and HRV under different BP states: hypotension, normotension, and hypertension. Using the MIMIC III database, 5 min segments of PPG and ECG signals were used to extract PRV and HRV, respectively. Several time-domain, frequency-domain, and nonlinear indices were obtained from these signals. Bland–Altman analysis, correlation analysis, and Friedman rank sum tests were used to compare HRV and PRV in each state, and PRV and HRV indices were compared among BP states using Kruskal–Wallis tests. The findings indicated that there were differences between PRV and HRV, especially in short-term and nonlinear indices, and although PRV and HRV were altered in a similar manner when there was a change in BP, PRV seemed to be more sensitive to these changes.


Heart ◽  
2018 ◽  
pp. heartjnl-2018-313592 ◽  
Author(s):  
Philipp Krisai ◽  
Annina Salome Vischer ◽  
Leo Kilian ◽  
Andrea Meienberg ◽  
Michael Mayr ◽  
...  

ObjectiveRecently, a cuffless blood pressure (BP) measurement device using pulse transit time (PTT) for beat-to-beat calculation of BP values has been validated over a short time period. However, it remains unknown how values obtained with this device compare with standard ambulatory measurements over a 24-hour period. We hypothesised that BP values measured by a cuffless PTT device (TestBP) are comparable with measurements by a standard upper arm cuff-based BP device (RefBP) in clinical practice over 24 hours.MethodsBetween May and December 2017, 71 individuals were prospectively included. Cuffless using the Somnotouch-NIBP (Somnomedics GmbH, Randersacker, Germany) and cuff-based standard 24-hour BP measurements were performed simultaneously on the left and right arm, respectively. The first RefBP measurement was used as calibration measurement for the TestBP.ResultsMean (±SD) age was 49.3 (15.1) years, and 51% were male. Mean 24-hour BP for TestBP and RefBP were 140.8 (20.0) versus 134.0 (17.3) mm Hg for systolic (p<0.0001) and 85.8 (14.1)versus79.3 (11.7) mm Hg for diastolic (p<0.0001) measurements, respectively. Mean absolute systolic and diastolic disagreements between TestBP and RefBP were 10.2 (7.2) and 8.2 (5.5) mm Hg, respectively. The number (percentage) of absolute differences between the mean 24-hour BP values of the TestBP and RefBP within 5, 10 and 15 mm Hg were 23 (32.4), 43 (60.6) and 54 (74.6) for systolic and 24 (33.8), 51 (71.8) and 65 (91.6) for diastolic measurements, respectively.ConclusionIn clinical practice over 24 hours, there was a significant difference between the TestBP and RefBP with higher systolic and diastolic BP measured with the cuffless PTT device. Reasons for this difference need to be investigated.Clinical trial registrationNCT03054688; Results.


Sensors ◽  
2019 ◽  
Vol 19 (3) ◽  
pp. 595 ◽  
Author(s):  
Kwang Lee ◽  
Jongryun Roh ◽  
Dongrae Cho ◽  
Joonho Hyeong ◽  
Sayup Kim

Hypertension is a well-known chronic disease that causes complications such as cardiovascular diseases or stroke, and thus needs to be continuously managed by using a simple system for measuring blood pressure. The existing method for measuring blood pressure uses a wrapping cuff, which makes measuring difficult for patients. To address this problem, cuffless blood pressure measurement methods that detect the peak pressure via signals measured using photoplethysmogram (PPG) and electrocardiogram (ECG) sensors and use it to calculate the pulse transit time (PTT) or pulse wave velocity (PWV) have been studied. However, a drawback of these methods is that a user must be able to recognize and establish contact with the sensor. Furthermore, the peak of the PPG or ECG cannot be detected if the signal quality drops, leading to a decrease in accuracy. In this study, a chair-type system that can monitor blood pressure using polyvinylidene fluoride (PVDF) films in a nonintrusive manner to users was developed. The proposed method also uses instantaneous phase difference (IPD) instead of PTT as the feature value for estimating blood pressure. Experiments were conducted using a blood pressure estimation model created via an artificial neural network (ANN), which showed that IPD could estimate more accurate readings of blood pressure compared to PTT, thus demonstrating the possibility of a nonintrusive blood pressure monitoring system.


2019 ◽  
Author(s):  
Jürgen Fortin ◽  
Dorothea Rogge ◽  
Christian Fellner ◽  
Doris Flotzinger ◽  
Julian Grond ◽  
...  

AbstractWearable sensors to continuously measure blood pressure (BP) and derived cardiovascular variables have the potential to revolutionize patient monitoring. Current wearable methods analyzing time components (e.g., pulse transit time) still lack clinical accuracy, whereas existing technologies for direct BP measurement are too bulky. Here we present a new art of continuous non-invasive arterial blood pressure monitoring (CNAP2GO). It directly measures BP by using a new “volume control technique” and could be used for small wearable sensors integrated in a finger ring. As a software prototype, CNAP2GO showed excellent BP measurement performance in comparison with invasive BP in 46 patients having surgery. The resulting pulsatile BP signal carries information to derive cardiac output and other hemodynamic variables. We show that CNAP2GO can be miniaturized for wearable approaches. CNAP2GO potentially constitutes the breakthrough for wearable sensors for blood pressure and flow monitoring in both ambulatory and in-hospital clinical settings.


2013 ◽  
Vol 39 (9) ◽  
pp. 1618-1625 ◽  
Author(s):  
Juan C. Ruiz-Rodríguez ◽  
Adolf Ruiz-Sanmartín ◽  
Vicent Ribas ◽  
Jesús Caballero ◽  
Alejandra García-Roche ◽  
...  

Sensors ◽  
2018 ◽  
Vol 18 (7) ◽  
pp. 2095 ◽  
Author(s):  
Toan Huynh ◽  
Roozbeh Jafari ◽  
Wan-Young Chung

One potential method to estimate noninvasive cuffless blood pressure (BP) is through measurement of pulse wave velocity (PWV), which can be characterized by measuring the distance and the transit time of the pulse between two arterial sites. To obtain the pulse waveform, bioimpedance (BI) measurement is a promising approach because it continuously reflects the change in BP through the change in the arterial cross-sectional area. Several studies have investigated BI channels in a vertical direction with electrodes located along the wrist and the finger to calculate PWV and convert to BP; however, the measurement systems were relatively large in size. In order to reduce the total device size for use in a PWV-based BP smartwatch, this study proposes and examines a horizontal BI structure. The BI device is also designed to apply in a very small body area. Our proposed structure is based on two sets of four-electrode BI interface attached around the wrist. The effectiveness of our system and approach is evaluated on 15 human subjects; the PWV values are obtained with various distances between two BI channels to assess the efficacy. The results show that our BI system can monitor pulse rate efficiently in only a 0.5 × 1.75 cm2 area of the body. The correlation of pulse rate from the proposed design against the reference is 0.98 ± 0.07 (p < 0.001). Our structure yields higher detection ratios for PWV measurements of 99.0 ± 2.2%, 99.0 ± 2.1%, and 94.8 ± 3.7% at 1, 2, and 3 cm between two BI channels, respectively. The measured PWVs correlate well with the BP standard device at 0.81 ± 0.08 and 0.84 ± 0.07 with low root-mean-squared-errors at 7.47 ± 2.15 mmHg and 5.17 ± 1.81 mmHg for SBP and DBP, respectively. Our results inform future designs of smart watches capable of measuring blood pressure.


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