Nanostructural Zinc Oxide Hollow Spheres Catalyzed Synthesis of 3, 4-Dihydropyrimidin-2(1H)-Ones under Solvent-Free Conditions
2011 ◽
Vol 233-235
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pp. 273-276
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Keyword(s):
A simple synthesis of 3,4-dihydropyrimidinones from the aldehyde, 1,3-dicarbonyl compound, and urea (thiourea) using nanostructural zinc oxide hollow spheres as the catalyst under solvent-free conditions is described. Compared with traditional Biginelli reactions, this method has advantages of excellent yields and short reaction time.