The Preparation and Characterization of Inclusion Complex of Ursolic Acid with γ-Cyclodextrin
2011 ◽
Vol 403-408
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pp. 712-716
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Keyword(s):
X Ray
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In order to increase the solubility of ursolic acid, the inclusion complexes of ursolic acid with γ-cyclodextrin were prepared by grinding, ultrasonic and stirring methods. The characterizations of the inclusion complexes were proved by x-ray powder diffraction, fourier transform infrared spectroscopy, differential scanning calorimetry and scanning electron microscopy. The results confirmed the interactions of ursolic acid with γ-cyclodextrin, indicating the formation of the inclusion complexes. In addition, grinding method is a better way of preparing inclusion complex of ursolic acid with γ-cyclodextrin.