Dynamic Self-Assembly Process of a Designed Peptide
2013 ◽
Vol 750-752
◽
pp. 1630-1634
In this paper, we reported the dynamic self-assembly process of an half-sequence ionic self-complementarity peptide CH3CO-Pro-Ser-Phe-Cys-Phe-Lys-Phe-Glu-Pro-NH2, which could self-assemble into stable nanofibers and formed hydrogel consisting of >99% water. The dynamic self-assembly process was detected by circular dichroism (CD) and atomic force microscopy (AFM). CD spectrum revealed that the mainly contents of the peptide were regular β-sheet structure. The data indicated that though the secondary structure of the peptide formed immediately, the microstructure of the self-assembly process of the designed peptide formed slowly. AFM image illustrated that the self-assembly process was layer-by-layer assembly.
Keyword(s):
2009 ◽
Vol 27
(3)
◽
pp. 1247
Keyword(s):
2006 ◽
Vol 10
(07)
◽
pp. 986-990