scholarly journals A High-Resolution Amperometric Acetylcholine Sensor Based on Nano-Assembled Carbon Nanotube and Acetylcholinesterase Thin Films

2008 ◽  
Vol 1 ◽  
pp. 1-9 ◽  
Author(s):  
Wei Xue ◽  
Tianhong Cui

We demonstrate a carbon nanotube based high-resolution biosensor for acetylcholine sensing. Carbon nanotubes are deposited on a silicon wafer in a repeated fashion with layer-by-layer nano self-assembly technique. With nano-assembled acetylcholinesterase molecules on the surface, the carbon nanotube biosensor is capable of detecting acetylcholine at an ultra-low concentration of 100 pM. The sensitivity of the acetylcholine sensor is measured as 7.2 µA/decade. The real-time measurement shows the response time of the biosensor is approximately 6 sec. Both the carbon nanotube film and the acetylcholinesterase film are crucial in the sensing process. Due to its high resolution, fast response, small size, and low cost, the carbon nanotube biosensor has tremendous potential for applications in medical research and clinical diagnosis.

2021 ◽  
pp. 004051752110441
Author(s):  
Qinghua Yu ◽  
Jinhua Jiang ◽  
Chuanli Su ◽  
Yaoli Huang ◽  
Nanliang Chen ◽  
...  

Flexible wearable strain sensors with excellent sensing performance have received widespread interest due to their superior application capability in the field of human-computer interaction, sports rehabilitation, and disease diagnosis. But at present, it is still a considerable challenge to exploit a flexible strain sensor with high sensitivity and wide sensing range that is easily manufactured, low-cost, and easily integrable into clothing. MXene is a promising material sensitive enough for flexible sensors due to its superior conductivity and hydrophilicity. The warp knitting weft insertion textile structure gives the fabric excellent elasticity, making it suitable as a flexible, stretchable substrate. Therefore, utilizing a polyester elastic fabric with a warp knitting weft insertion structure, a fabric strain sensor with high sensitivity and wide sensing range prepared by layer-by-layer self-assembly of polyvinyl alcohol layers and MXene layers is reported in this study. The strain sensor exhibits high sensitivity (up to 288.43), a wide sensing range (up to 50%), fast response time (50 ms), ultra-low detection limit (a strain of 0.067%), excellent cycle stability (1000 cycles), and good washability. Besides, affixing the MXene/polyvinyl alcohol/polyester elastic fabric strain sensor on the joints can detect the movement of limbs. Therefore, the MXene/polyvinyl alcohol/polyester elastic fabric strain sensor demonstrates potential application opportunities in smart wearable electronic devices, and the researcher can also apply this method in the production of other flexible, intelligent wearable devices.


Author(s):  
Wei Xue ◽  
Tianhong Cui

The fabrication and characterization of single-walled carbon nanotube (SWNT) multilayers, micropatterns and interconnections on plastic substrates are reported in this paper. The SWNT-based multilayers and devices are fabricated with a simple, fast, inexpensive, low-temperature, and highly efficient technique combining layer-by-layer (LbL) nano self-assembly, microlithography, and lift-off techniques. The SWNT multilayers are alternating layers of SWNTs and poly (dimethyldiallylammonium chloride) (PDDA). Lithography and lift-off techniques are used to pattern the SWNT multilayers. SWNT microstructures with linewidth of 5 μm are fabricated and characterized. The thickness of a (PDDA/SWNT) bi-layer is approximately 76 Å. Two-terminal SWNT thin film based interconnections are fabricated on flexible substrates. Current-voltage (I-V) characterization and four-point probe measurement show that the resistance of the interconnection is nonlinearly inversely proportional to the number of the assembled SWNT layers. The nano-assembled polymer/SWNT composite can be used in many applications due to its low cost, light weight, and long lifetime.


2007 ◽  
Vol 121-123 ◽  
pp. 483-486
Author(s):  
Xiao Ping Zou ◽  
H. Abe ◽  
Toru Shimizu ◽  
A. Ando ◽  
H. Tokumoto ◽  
...  

Site-selective growth of multi-walled carbon nanotubes (MWCNTs) from an iron oxide nanoparticle catalyst patterned by drying-mediated self-assembly technique is present. The ethanol solution of the iron nitrate was employed as catalyst precursor. The catalyst precursor was mounted on silicon wafer by dip-coating. After evaporation of solvent at room temperature, the catalyst pattern formed. The catalyst pattern was employed to synthesize carbon nanotube pattern by chemical vapor deposition of ethanol vapor after oxidation of iron nitrate. The patterned array of MWCNTs was obtained with a dot size of around 5 'm and the distance of about 25 'm. The present method offers a simple and cost-effective method to grow carbon nanotubes with self-assembled patterns.


Author(s):  
Bo Zhang ◽  
Tony Zhengyu Cui

The manufacture and characterization of glucose biosensor based on layer by layer self assembled graphene are presented. Due to self assembly technique and flexible polymer substrate, the cost of the biosensor is very competitive. The resolution of the graphene based biosensor reaches down to 10 pM, which shows greater advantages over CNT based biosensor under the same conditions. The response time of graphene biosensor is less than 3 s, which is much faster than other materials and methods. This work demonstrates that graphene and polymers are very promising materials for the applications of low-cost glucose biosensors.


2017 ◽  
Vol 5 (16) ◽  
pp. 7482-7493 ◽  
Author(s):  
Yi-Tian Huang ◽  
He Zhang ◽  
Xue-Juan Wan ◽  
Da-Zhu Chen ◽  
Xue-Fei Chen ◽  
...  

Carbon nanotube-incorporated double-walled phase-change microcapsules with excellent thermal and mechanical properties were realized via a facile layer-by-layer self-assembly technique.


The Analyst ◽  
2015 ◽  
Vol 140 (3) ◽  
pp. 820-826 ◽  
Author(s):  
Shuyue Guo ◽  
Lin Xu ◽  
Bingbing Xu ◽  
Zhixia Sun ◽  
Lihao Wang

In this work, a nanocomposite film electrode containing polyoxometalate (POM) clusters K6P2W18O62 (P2W18), carbon nanotubes (CNTs) and Au nanoparticles (AuNPs) was fabricated by a layer-by-layer self-assembly technique.


2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Qiangying Yi ◽  
Gleb B. Sukhorokov ◽  
Jin Ma ◽  
Xiaobo Yang ◽  
Zhongwei Gu

Phase change materials absorb the thermal energy when changing their phases (e.g., solid-to-liquid) at constant temperatures to achieve the latent heat storage. The major drawbacks such as limited thermal conductivity and leakage prevent the PCMs from wide application in desired areas. In this work, an environmentally friendly and low cost approach, layer-by-layer (LbL) assembly technique, was applied to build up ultrathin shells to encapsulate the PCMs and therefore to regulate their changes in volume when the phase change occurs. Generally, the oppositely charged strong polyelectrolytes Poly(diallyldimethylammonium chloride) (PDADMAC) and Poly(4-styrenesulfonic acid) sodium salt (PSS) were employed to fabricate multilayer shells on emulsified octadecane droplets using either bovine serum albumin (BSA) or sodium dodecyl sulfate (SDS) as surfactant. Specifically, using BSA as the surfactant, polyelectrolyte encapsulated octadecane spheres in size of ∼500 nm were obtained, with good shell integrity, high octadecane content (91.3% by mass), and good thermal stability after cycles of thermal treatments.


2007 ◽  
Vol 124-126 ◽  
pp. 1309-1312
Author(s):  
Nguyen Duc Hoa ◽  
Nguyen Van Quy ◽  
Gyu Seok Choi ◽  
You Suk Cho ◽  
Se Young Jeong ◽  
...  

A new type of gas sensor was realized by directly depositing carbon nanotube on nano channels of the anodic alumina oxide (AAO) fabricated on p-type silicon substrate. The carbon nanotubes were synthesized by thermal chemical vapor deposition at a very high temperature of 1200 oC to improve the crystallinity. The device fabrication process was also developed. The contact of carbon nanotubes and p-type Si substrate showed a Schottky behavior, and the Schottky barrier height increased with exposure to gases while the overall conductivity decreased. The sensors showed fast response and recovery to ammonia gas upon the filling (400 mTorr) and evacuation.


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