Contribution of Three-Dimensional Trabecular Bone Microstructure of the Proximal Femur to its Mechanical Properties as Assessed by Micro-Finite Element Analysis

2006 ◽  
Vol 321-323 ◽  
pp. 278-281
Author(s):  
Wen Quan Cui ◽  
Ye Yeon Won ◽  
Myong Hyun Baek ◽  
Kwang Kyun Kim

The purpose of this study was to investigate the contribution of the microstructural properties of trabecular bone in predicting its elastic modulus in the intertrochanteric region. A total of 15 trabecular bone core specimens were obtained from the proximal femurs of patients undergoing total hip arthroplasty. The micro-computed tomography (micro-CT) was used to scan each specimen to obtain micro-morphology. Microstructural parameters were directly calculated using software. Micro-CT images were converted to micro-finite element model using meshing technique, and then micro-finite element analysis (FEA) was performed to assess the mechanical property (Young’s modulus) of trabecular bone. The results showed that the ability to explain this variance of Young’s modulus is improved by combining the structural indices with each other. It suggested that assessment of bone microarchitecture should be added as regards detection of osteoporosis and evaluation of the efficacy of drug treatments for osteoporosis.

2013 ◽  
Vol 10 (4) ◽  
pp. 189-195 ◽  
Author(s):  
W. X. Niu ◽  
L. J. Wang ◽  
T. N. Feng ◽  
C. H. Jiang ◽  
Y. B. Fan ◽  
...  

Finite element analysis (FEA) is a powerful tool in biomechanics. The mechanical properties of biological tissue used in FEA modeling are mainly from experimental data, which vary greatly and are sometimes uncertain. The purpose of this study was to research how Young’s modulus affects the computations of a foot-ankle FEA model. A computer simulation and an in-vitro experiment were carried out to investigate the effects of incremental Young’s modulus of bone on the stress and strain outcomes in the computational simulation. A precise 3-dimensional finite element model was constructed based on an in-vitro specimen of human foot and ankle. Young’s moduli were assigned as four levels of 7.3, 14.6, 21.9 and 29.2 GPa respectively. The proximal tibia and fibula were completely limited to six degrees of freedom, and the ankle was loaded to inversion 10° and 20° through the calcaneus. Six cadaveric foot-ankle specimens were loaded as same as the finite element model, and strain was measured at two positions of the distal fibula. The bone stress was less affected by assignment of Young’s modulus. With increasing of Young’s modulus, the bone strain decreased linearly. Young’s modulus of 29.2 GPa was advisable to get the satisfactory surface strain results. In the future study, more ideal model should be constructed to represent the nonlinearity, anisotropy and inhomogeneity, as the same time to provide reasonable outputs of the interested parameters.


2020 ◽  
Vol 2020 ◽  
pp. 1-11 ◽  
Author(s):  
Chunlai Tian ◽  
Pengfei Duan

Composite has been widely used in various fields due to its advanced performance. To reveal the relation between the mechanical properties of the composite and that of each individual component, finite element analysis (FEA) has usually been adopted. In this study, in order to predict the mechanical properties of hard coating on a soft polymer, the response of this coating system during nanoindentation was modelled. Various models, such as a viscoelastic model and fitting model, were adopted to analyse the indentation response of this coating system. By varying the substrate properties (i.e., Young’s modulus, viscoelasticity, and Poisson’s ratio), Young’s modulus, energy loss, and the viscoelastic model of the coating system were analysed, and how the mechanical properties of the substrate will affect the indentation response of the coating system was discussed.


2011 ◽  
Vol 133 (6) ◽  
Author(s):  
Srinidhi Nagaraja ◽  
Oskar Skrinjar ◽  
Robert E. Guldberg

Although microdamage is known to accumulate in trabecular bone with overloading and aging, the tissue-level stresses and strains associated with local bone failure are not well known. Local correlation of microdamage with microstructural stresses and strains requires methods to accurately register histological sections with micro-computed tomography (micro-CT) based finite element models. In addition, the resolution of correlation (i.e., grid size) selected for analysis may affect the observed results. Therefore, an automated, repeatable, and accurate image registration algorithm was developed to determine the range of local stresses and strains associated with microdamage initiation. Using a two-dimensional rigid registration algorithm, bone structures from histology and micro-CT imaging were aligned. Once aligned, microdamaged regions were spatially correlated with local stresses and strains obtained from micro-CT based finite element analysis. Using this more sophisticated registration technique, we were able to analyze the effects of varying spatial grid resolution on local stresses and strains initiating microdamage. The results indicated that grid refinement to the individual pixel level (pixel-by-pixel method) more precisely defined the range of microdamage initiation compared to manually selected individual damaged and undamaged trabeculae. Using the pixel-by-pixel method, we confirmed that trabecular bone from younger cows sustained higher local strains prior to microdamage initiation compared to older bone.


2014 ◽  
Vol 64 ◽  
pp. 1-8 ◽  
Author(s):  
K. Zhuravleva ◽  
R. Müller ◽  
L. Schultz ◽  
J. Eckert ◽  
A. Gebert ◽  
...  

Bone ◽  
2000 ◽  
Vol 26 (5) ◽  
pp. 519-524 ◽  
Author(s):  
J.P.W van den Bergh ◽  
G.H van Lenthe ◽  
A.R.M.M Hermus ◽  
F.H.M Corstens ◽  
A.G.H Smals ◽  
...  

2021 ◽  
Vol 11 (7) ◽  
pp. 3243
Author(s):  
Cheol-Jeong Kim ◽  
Seung Min Son ◽  
Sung Hoon Choi ◽  
Tae Sik Goh ◽  
Jung Sub Lee ◽  
...  

The aim of this study was to analyze the spinal stability and safety after posterior spinal fusion with various fixation segments and screw types in patients with an osteoporotic thoracolumbar burst fracture based on finite element analysis (FEA). To realize various osteoporotic vertebral fracture conditions on T12, seven cases of Young’s modulus, namely 0%, 1%, 5%, 10%, 25%, 50%, and 100% of the Young’s modulus, for vertebral bones under intact conditions were considered. Four types of fixation for thoracolumbar fracture on T12 (fixed with T11-L1, T10-T11-L1, T11-L1-L2, and T10-T11-L1-L2) were applied to the thoracolumbar fusion model. The following screw types were considered: pedicle screw (PS) and cortical screw (CS). Using FEA, four motions were performed on the fixed spine, and the stress applied to the screw, peri-implant bone (PIB), and intervertebral disc (IVD) and the range of motion (ROM) were calculated. The lowest ROM calculated corresponded to the T10-T11-L1-L2 model, while the closest to the intact situation was achieved in the T11-L1-L2 fixation model using PS. The lowest stress in the screw and PB was detected in the T10-T11-L1-L2 fixation model.


2010 ◽  
Vol 25 (6) ◽  
pp. 1131-1136 ◽  
Author(s):  
Dejun Ma ◽  
Chung Wo Ong

In our previous study, we modeled the indentation performed on an elastic–plastic solid with a rigid conical indenter by using finite element analysis, and established a relationship between a nominal hardness/reduced Young’s modulus (Hn/Er) and unloading work/total indentation work (We/Wt). The elasticity of the indenter was absorbed in Er ≡ 1/[(1 − ν2)/E + (1 − νi2)/Ei], where Ei and νi are the Young’s modulus and Poisson’s ratio of the indenter, and E and ν are those of the indented material. However, recalculation by directly introducing the elasticity of the indenter show that the use of Er alone cannot accurately reflect the combined elastic effect of the indenter and indented material, but the ratio η = [E/(1 − ν2)]/[Ei/(1 − νi2)] would influence the Hn/Er–We/Wt relationship. Thereby, we replaced Er with a combined Young’s modulus Ec ≡ 1/[(1 − ν2)/E + 1.32(1 − νi2)/Ei] = Er/[1 + 0.32η/(1 + η)], and found that the approximate Hn/Ec–We/Wt relationship is almost independent of selected η values over 0–0.3834, which can be used to give good estimates of E as verified by experimental results.


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