Different Synthesis Routes for Hydroxyapatite Nanoparticles by Mechanical Stirring
Nanosized hydroxyapatite (HA) with crystallinity and composition similar to bone apatite has been widely investigated in the last years, due to their excellent biocompatibility in bone replacement applications. This bioceramic can be synthesized by many wet chemical and mechanochemical methods. In this paper, nanosized hydroxyapatite powders were synthesized by two wet chemical routes using mechanical stirring method. The first route was used for HA synthesis from CaCl2.2H2O and Na3PO4.12H2O solutions and the second route was from Ca (OH)2 and H3PO4 solutions. The synthesized HA nanoparticles were characterized by Dynamic Light Scattering, BET Surface Area analysis, X-ray Diffraction, Infrared Spectroscopy, chemical analysis and Scanning Electron Microscopy. The results indicated that HA nanoparticles were successfully synthesized by both wet chemical precipitation routes and all powders presented a Ca/P ratio similar to stoichiometric HA, nanoneedles morphology and single HA crystalline phase.