scholarly journals The Effects of Tibolone in Breast Cancer Cell Lines: The Role of Tibolone in Phospholipase D Signal Transduction Pathway

2003 ◽  
Vol 6 (1) ◽  
pp. 1
Author(s):  
Ki Wook Chung ◽  
Soo Jung Ahn ◽  
Sung Won Kim ◽  
Wonshik Han ◽  
Hee Joung Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Signal Transduction ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Phospholipase D ◽  
Signal Transduction Pathway ◽  
Breast Cancer Cell Lines ◽  
Transduction Pathway

scholarly journals Highly expressed SLCO1B3 inhibits the occurrence and development of breast cancer and can be used as a clinical indicator of prognosis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tiantian Tang ◽  
Guiying Wang ◽  
Sihua Liu ◽  
Zhaoxue Zhang ◽  
Chen Liu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Proliferation ◽  
Cancer Cells ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cells ◽  
Migration And Invasion ◽  
Breast Cancer Cell Lines

AbstractThe role of organic anion transporting polypeptide 1B3 (SLCO1B3) in breast cancer is still controversial. The clinical immunohistochemical results showed that a greater proportion of patients with negative lymph nodes, AJCC stage I, and histological grade 1 (P < 0.05) was positively correlated with stronger expression of SLCO1B3, and DFS and OS were also increased significantly in these patients (P = 0.041, P = 0.001). Further subgroup analysis showed that DFS and OS were significantly enhanced with the increased expression of SLCO1B3 in the ER positive subgroup. The cellular function assay showed that the ability of cell proliferation, migration and invasion was significantly enhanced after knockdown of SLCO1B3 expression in breast cancer cell lines. In contrast, the ability of cell proliferation, migration and invasion was significantly reduced after overexpress the SLCO1B3 in breast cancer cell lines (P < 0.05). Overexpression or knockdown of SLCO1B3 had no effect on the apoptotic ability of breast cancer cells. High level of SLCO1B3 expression can inhibit the proliferation, invasion and migration of breast cancer cells, leading to better prognosis of patients. The role of SLCO1B3 in breast cancer may be related to estrogen. SLCO1B3 will become a potential biomarker for breast cancer diagnosis and prognosis assessment.

scholarly journals Role of secreted type I collagen derived from stromal cells in two breast cancer cell lines

2014 ◽  
Vol 8 (2) ◽  
pp. 507-512 ◽  
Author(s):  
SUNG HOON KIM ◽  
HYE YOON LEE ◽  
SEUNG PIL JUNG ◽  
SANGMIN KIM ◽  
JEONG EON LEE ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Stromal Cells ◽  
Type I Collagen ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Type I

Role of efflux pump activity in lapatinib/caelyx combination in breast cancer cell lines

2009 ◽  
Vol 20 (10) ◽  
pp. 918-925 ◽  
Author(s):  
Ivan Vannini ◽  
Wainer Zoli ◽  
Francesco Fabbri ◽  
Paola Ulivi ◽  
Anna Tesei ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Efflux Pump ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Pump Activity

scholarly journals Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e67149 ◽  
Author(s):  
Su-Lin Lee ◽  
Chih-Chien Chou ◽  
Hsiao-Ching Chuang ◽  
En-Chi Hsu ◽  
Po-Chen Chiu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Functional Role ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Akt Phosphorylation ◽  
Integrin Linked Kinase

QS283. Effect of Activin ond Smad 3 Signal Transduction on Breast Cancer Cell Lines

2008 ◽  
Vol 144 (2) ◽  
pp. 379 ◽  
Author(s):  
Supurna Ghosh ◽  
Kelly Fitzgerald ◽  
Kerstyn Syc Bryce ◽  
Jacqueline S. Jeruss
Keyword(s):  
Breast Cancer ◽  
Signal Transduction ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Smad 3
Sign in / Sign up

Export Citation Format

Share Document