scholarly journals Low grade transitional cell carcinoma of the urethra successfully treated with only intraurethral instillation of Mitomycin-C

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Sharfuddeen A. Mashi ◽  
Sani A. Aji ◽  
Muzzammil Abdullahi ◽  
Bashir Yunusa ◽  
Sani U. Alhassan
Keyword(s):  
Mitomycin C ◽  
Urothelial Cancer ◽  
Transitional Cell ◽  
Significant Risk ◽  
Low Grade ◽  
Short Segment ◽  
Urinary Tract Symptoms ◽  
History Of ◽  
Posterior Urethra ◽  
Lower Urinary

Urethral cancer is very rare disease, accounting for less than 0.5% of incidences of malignancies. Data on its management are scarce due to the rare nature of the cases. We present a 34-year-old man, who presented to our hospital with a month history of hematuria. He had no lower urinary tract symptoms and no significant risk factors for urothelial cancer. He was evaluated and found to have lesions in the posterior urethra on urethrocytoscopy, biopsy of which revealed a low-grade urothelial cancer. He was counselled and had 6 courses of intraurethral instillation of 40mg of Mitomycin-C diluited in 50mL of saline held in the urethra with penile clamp for 30 minutes. The hematuria stopped after the second course, a repeat urethrocystoscopy 6 months after the completion of the chemotherapy, showed resolution of the lesion and repeat biopsy showed no evidence of malignancy. However, the patient developed short segment partial penile urethral stricture that was treated with dilatation. In conclusion, low-grade urothelial cancer of the urethra can be successfully cured with Intraurethral instillation of Mitomycin-C, without prior transurethral resection.

Primary diffuse large B cell lymphoma (DLBCL) of the prostate presenting with lower urinary tract symptoms (LUTS)

2020 ◽  
Vol 13 (12) ◽  
pp. e236280
Author(s):  
Ayesha Nusrat ◽  
Syed Muhammad Nazim
Keyword(s):  
Urinary Tract ◽  
B Cell ◽  
Lower Urinary Tract ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Urinary Tract Symptoms ◽  
History Of ◽  
Large B Cell ◽  
Lower Urinary

Malignant lymphomas of the prostate are very rare tumours and are generally not considered in the clinical or pathological diagnosis of prostatic enlargement. We report a case of a 56-year-old man who presented with long-standing history of low back pain and a 2-month history of voiding lower urinary tract symptoms. He denied any history of urinary retention, trauma, catheterisation or any constitutional symptoms. Examination revealed no lymphadenopathy and hepatosplenomegaly. Digital rectal examination showed an irregular, moderately enlarged nodular prostate. His prostate-specific antigen was 1.54 ng/mL. MRI of the pelvis did not show any focal lesion apart from abnormal signal intensity in the central zone. Bone scan was negative. Transrectal ultrasound-guided prostate biopsy revealed diffuse large B cell lymphoma. Bone marrow biopsy and whole body positron emission tomography/CT were unremarkable. The patient achieved complete remission after receiving six cycles of R-CHOP chemotherapy.

scholarly journals Onset of hydronephrosis and lower urinary tract symptoms in a previously healthy young man: Phyllodes tumour of the prostate as a potential diagnosis.

2014 ◽  
Vol 8 (7-8) ◽  
pp. 561 ◽  
Author(s):  
Matteo Ferrari ◽  
Umberto Capitanio ◽  
Nathalie Rizzo ◽  
Massimo Freschi ◽  
Francesco Montorsi ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Malignant Disease ◽  
Specific Antigen ◽  
Low Grade ◽  
Total Prostate Specific Antigen ◽  
Urinary Tract Symptoms ◽  
Phyllodes Tumour ◽  
Transvesical Approach ◽  
Tomography Scan ◽  
Lower Urinary

We report the case of a 50-year-old healthy man with early onset of micturition symptoms associated with an elevated total prostate-specific antigen. On physical examination, we found an enlarged prostate; a first-line ultrasound of the urinary tract revealed local disease which covered the entire small pelvis. A computed tomography scan confirmed the presence of a 12.5 × 11.0 × 9.5-cm multicystic prostatic mass, compressing the bladder and pelvic ureters, associated with right hydronephrosis. Renal function was preserved and prostatic biopsies was negative for malignant disease. The mass was completely removed through transvesical approach and histological analysis diagnosed a low-grade phyllodes tumour of the prostate. The patient was free of local recurrence and metastasis 36 months after surgery.

scholarly journals Laparoscopic removal of a pelvic cyst associated with obstructedmegaureter and dysplastic renal remnant

2013 ◽  
Vol 3 (2) ◽  
pp. 159 ◽  
Author(s):  
Michael L. Pianezza ◽  
Eric P. Estey
Keyword(s):  
Lower Urinary Tract ◽  
Bladder Wall ◽  
Renal Tissue ◽  
Urinary Tract Symptoms ◽  
History Of ◽  
The Right ◽  
Laparoscopic Removal ◽  
Pelvic Cyst ◽  
Surgical Option ◽  
Lower Urinary

We report a case of a 41-year-old man with a solitary functioningleft kidney and history of chronic pelvic discomfort associatedwith lower urinary tract symptoms. Imaging revealed a largecystic structure in the pelvis attached to a dilated tortuous ureteron the right with congenital absence of the right kidney. The patientunderwent laparoscopic removal of the pelvic cyst and dilatedright ureter. Pathological assessment revealed mesonephric remnantsrepresenting dysplastic renal tissue attached to a dilated andobstructed megaureter, extending into the bladder wall and forminga large pelvic cyst. The patient’s symptoms resolved. A laparoscopicapproach represents an excellent surgical option for pelvicpathology.Nous décrivons le cas d’un homme de 41 ans porteur d’un seulrein fonctionnel (gauche) et ayant des antécédents de douleurspelviennes chroniques liées à des symptômes affectant les voiesurinaires inférieures. Les épreuves d’imagerie ont révélé une massekystique volumineuse au niveau du pelvis, une dilatation et unesinuosité urétérales du côté droit et l’absence congénitale derein droit. Le patient a subi une ablation par laparoscopie du kystepelvien et de la section dilatée de l’uretère droit. L’évaluationpathologique a révélé des vestiges mésonéphriques constituésde tissu rénal dysplasique lié à un méga-uretère obstrué avec dilatationkystique se prolongeant dans la paroi vésicale et formant ainsiun kyste pelvien volumineux. Les symptômes du patient ont disparu.Une approche laparoscopique représente une excellenteoption chirurgicale en présence de pathologie pelvienne.

scholarly journals Urachal Mucinous Cystadenocarcinoma

2019 ◽  
Vol 12 (1) ◽  
pp. e228089
Author(s):  
Ryan Pereira ◽  
Stephen McGeorge ◽  
Marlon Perera ◽  
Ian Vela
Keyword(s):  
Bladder Wall ◽  
Pelvic Mass ◽  
Pubic Symphysis ◽  
Cystic Mass ◽  
Pelvic Lymphadenectomy ◽  
Urachal Remnant ◽  
Urinary Tract Symptoms ◽  
History Of ◽  
Open Excision ◽  
Lower Urinary

A 57-year-old man presented with a 6-month history of pelvic fullness. He had no lower urinary tract symptoms or altered bowel habits. On examination, there was a non-tender pelvic mass which extended from the pubic symphysis to the level of the umbilicus. CT scan of the abdomen demonstrated a 22×11×11 cm cystic mass arising from the pelvis extending into the midline and superiorly to the umbilicus. Other than raised carcinoembryonic antigen of 7.6 ng/mL (<5.0), the remainder of his blood test were unremarkable. Flexible cystoscopy demonstrated a convex deformity of the bladder wall in keeping with the compression and displacement as seen on the CT. The patient underwent an open excision of the cystic structure (urachal remnant), partial cystectomy, partial excision of anterior abdominal wall and pelvic lymphadenectomy. A check cystogram performed 12 days following the initial operation was unremarkable.

scholarly journals Foreign body in urinary bladder: our experience and review of literature

2019 ◽  
Vol 6 (12) ◽  
pp. 4327 ◽  
Author(s):  
Mohd Hamid Shafique Ahmed ◽  
Prakash W. Pawar ◽  
Ajit S. Sawant ◽  
Jitendra Sakharani ◽  
Amandeep Arora ◽  
...  
Keyword(s):  
Foreign Body ◽  
Urinary Bladder ◽  
Foreign Bodies ◽  
Clinical Presentation ◽  
Presentation Mode ◽  
Medical College ◽  
Urinary Tract Symptoms ◽  
History Of ◽  
Lower Urinary

Background: The objective of the study was to study clinical presentation, mode of insertion, and management of intravesical foreign bodies in patients treated at our hospital.Methods: This was a retrospective study conducted between January 2018 to June 2019. Six patients underwent treatment for urinary bladder foreign body at Lokmanya Tilak Municipal Medical College and Sion Hospital, Mumbai, Maharashtra, India. Medical records were analyzed retrospectively with regard to nature of foreign body, each patient’s clinical presentation, the mode of insertion and how the foreign was managed.Results: A total of six foreign bodies were retrieved from patients’ urinary bladders. The patients range in age from 28 to 65 years (mean age was 45 years). The Clinical presentation includes Lower urinary tract symptoms. Four patients were male and two were female. Circumstance of insertion was iatrogenic in 5 patients and self-insertion in 1 patient. Five patients were treated endoscopically (cystoscopy retrieval with or without cystolithotrity) and one patient with supra pubic cystostomy. Post-operative hospital stay was of 1 to 2 days. Mean follow up period was 3 months. Psychiatric referral and counseling were done in patients with history of self-insertion of foreign body in urinary bladder.Conclusions: Foreign body in the urinary bladder remain a challenge to the urologist. Removal of the foreign body without injury to the urinary bladder or the urethra gives good outcome.

scholarly journals Flexible Cystoscopy a Valuable Diagnostic Lool for Lower Urinary Tract Pathology

2020 ◽  
Vol 23 (2) ◽  
pp. 151-153
Author(s):  
Md Rokonuzzaman Khan ◽  
Fazal Naser ◽  
Moazzam Hossain ◽  
Mostafizur Rahman
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Kidney Diseases ◽  
Transitional Cell ◽  
Intravenous Urography ◽  
Low Grade ◽  
Cross Sectional ◽  
Flexible Cystoscopy ◽  
Diagnostic Protocol ◽  
Lower Urinary

Objective: To assess the role of flexible cystoscopy in the diagnosis of lower urinary tract pathology and its suitability as a routine diagnostic protocol in outdoor patients. Methods: The cross sectional study was conducted at the advanced centre of kidney diseases and urology, Dhaka central international medical college, Dhaka from Jan 2016 to jan2019. All adult patients presenting with lower urinary symptoms to outdoor department were included. Flexible Cystoscopy was performed as a outdoor based procedure without sedation. Results: Of the 249 patients in the study,198(79%) were male and 51(21%) were female. Lower urinary tract pathologies were found in 192(72%) patients. The most common pathology among males was enlarged prostate 56(31%) patients. Urethral stricture, bladder neck high were found 23(11%),21(10%) respectively. Among females, urethral stenosis was the most common pathology in 23(32%)patients. Transitional cell carcinoma was seen in 11(4.4%) patients having hematuria with inconclusive ultrasound and intravenous urography. .All patients tolerated the procedure well with no procedure related complaints. Conclusion: Flexible cystoscopy is an effective, well tolerated and easy way of detecting lower urinary tract pathologies. It can alter the management as well as support the diagnosis and management. It is also helpful in routine surveillance of bladder tumours of low grade and low stage. Flexible cystoscopy should therefore be used as routine diagnostic protocol in outdoor practice. Bangladesh Journal of Urology, Vol. 23, No. 2, July 2020 p.151-153

scholarly journals 646 A Review of The Urodynamic Referral Pathway and The Accuracy of Urodynamic Study Requests

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
M Breish ◽  
C Harding ◽  
S Biswas
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Great Majority ◽  
Detrusor Underactivity ◽  
Dysfunctional Voiding ◽  
Urinary Tract Symptoms ◽  
History Of ◽  
And Storage ◽  
Current Pathway ◽  
Lower Urinary

Abstract Aim Urodynamic studies (UDS) are physiological measurements of voiding and storage function of the lower urinary tract that are commonly performed in clinical practice to investigate bothersome lower urinary tract symptoms. Despite considerable efforts to improve UDS, standardisation of the practice remains to be challenging. This audit thus, presents a review the current UDS referral process and analysis of the clinical details included on urodynamic requests. Method This audit included retrospective data from 112 patients between March and Oct 2020, 98 of which had UDS performed. Patient electronic records, referral forms and clinic letters were all used for data collection. Results Data shows that 47% of patients were females with average age of 56 years, range (16-86) years. The reason of UDS was clearly stated in 8 referrals only and the clinical examination findings were clearly mentioned in 31% only. More than three quarters of patients (i.e., 77%) had assessment of post void residual prior to UDS, but half of the proportion had no history of relevant medications. In 98 patients who had UDS done, the main findings showed that 4 patients had normal studies, 3 with dysfunctional voiding, 7 had bladder outflow obstruction, 32 patients were diagnosed with detrusor overactivity, 12 had stress incontinence and 7 showed detrusor underactivity. Conclusions Finding of this audit clearly suggest a level of unclarity in the great majority of referrals. Evidently, key history of relevant medication is overlooked in half of the referrals. Improvements to the current pathway to UDS is therefore pivotal.

Urology

2021 ◽  
pp. 449-490
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract Symptoms ◽  
Lower Urinary Tract ◽  
Transitional Cell ◽  
Urinary Tract Symptoms ◽  
Prostatic Enlargement ◽  
Urinary Tract Stones ◽  
Ageing Male ◽  
Tract Disease ◽  
Lower Urinary

This chapter explores urology, starting with the symptoms and signs. Symptoms in urology include pain, haematuria, urinary incontinence, male sexual dysfunction, haemotospermia, and lower urinary tract symptoms. Lower urinary tract symptoms refer to a group of symptoms that typically affect the ageing male. It is often caused by bladder outflow obstruction (BOO) related to prostatic enlargement and includes symptoms related to both voiding and storage. The chapter then looks at the investigations of urinary tract disease, detailing laboratory investigations, radiology investigations, and endoscopy. It deals with urinary tract stones; obstruction of the ureter; benign prostatic hyperplasia; stricture of the urethra; scrotal swellings; disorders of the foreskin; common conditions of the penis; and erectile dysfunction. The chapter also considers adenocarcinoma of the kidney; transitional cell tumours; adenocarcinoma of the prostate; carcinoma of the penis; testicular tumours; haematuria; acute urinary retention (AUR); and acute testicular pain.

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