scholarly journals A case of post-inflammatory warty dyskeratoma of the chest: Other dermoscopic features

2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Vito Ingordo ◽  
Gerardo Ferrara ◽  
Irene Ingordo ◽  
Giuseppe Argenziano
Keyword(s):  
Rare Condition ◽  
Benign Neoplasm ◽  
Skin Tumors ◽  
Vascular Pattern ◽  
Nodular Lesions ◽  
Brown Pigmentation

Warty Dyskeratoma (WD) is a rare condition consisting in single or multiple papular or nodular lesions of the skin or of the oral mucosamucosa. Histologically, a cupshaped epidermal invagination centred by a plug of epidermal hyperparakeratosis with suprabasal acantholysis and dyskeratosis is typically observed. A case of post-inflammatory WD, which was also observed by dermoscopy, is described. Dermoscopy showed an eight-shape whitish collarette surrounded by light brown pigmentation. A central white structureless area with an adjacent rosette were observed. Some small rust-coloured blood crusts were also observed in the centre of the lesion; no prominent vascular pattern was detected. The etiopathogenesis of this benign neoplasm could be multifactorial. Dermoscopy of WD is not specific but may help to ruling out other skin tumors.

scholarly journals Dermoscopy of a non-pigmented eccrine poroma

2016 ◽  
Vol 1 (3) ◽  
Author(s):  
Maria Clara De Diego ◽  
Julieta Ruiz Beguerie
Keyword(s):  
Amelanotic Melanoma ◽  
Skin Tumors ◽  
Vascular Pattern ◽  
Clinical Appearance ◽  
Lower Back ◽  
Adnexal Tumor ◽  
Cherry Blossom ◽  
Vascular Structures ◽  
Slow Growing ◽  
Eccrine Poroma

<p>Eccrine poroma is a benign adnexal tumor arising from cells of the outer layer of the acrosyringium and upper dermal eccrine duct. It generally appears as a solitary, slow growing, sessile, pink-to-red and well-circumscribed papule, plaque or nodule. It is usually located on the palms and soles but it may also develop on other locations. Its clinical appearance can resemble other types of tumors such as hypo- or amelanotic melanoma. Dermoscopy has  improved the evaluation of skin tumors. In the case of eccrine poroma, there are some studies that have described its dermoscopic findings. These mainly focus on its vascular structures. We present an 82-year-old patient who developed a 2×3-cm eccrine poroma on his lower back. Dermoscopy demonstrated the presence of a polymorphous vascular pattern displaying mostly linear looped (irregular hairpin-like) and “leaf-flower-like” vessels (“cherry-blossom” and “chalice-like”), with some resembling “cactus-like” structures. Only a few linear coiled (glomerular) and linear helical (corkscrew) vessels were observed. Some of these vascular structures were surrounded by a whitish-to-pink halo. Moreover, some pink structureless areas were present. We highlight the finding of the “leaf-flower-like” vessels, as these are vascular structures that have not been described in other types of skin tumors.</p>

scholarly journals Intussuscepted Sigmoid Colonic Lipoma Mimicking Carcinoma Rectum

2016 ◽  
pp. 56-58
Author(s):  
Sharmistha Roy ◽  
Samiron Kumar Mondal ◽  
Tapash Kumar Maitra
Keyword(s):  
Sigmoid Colon ◽  
Female Patient ◽  
Rare Condition ◽  
Benign Neoplasm ◽  
Colonic Lipoma ◽  
Carcinoma Rectum

Adult colorectal intussusception is a relatively rare condition. It is different from that of a child in that, most cases have an organic etiology like a malignant or benign neoplasm. This is a 40 year female patient presenting with passage of blood and mucous per rectum later diagnosed as sigmoidorectal intussusception due to submucous lipoma in sigmoid colon that was protruding through anus giving the appearance of a large polypoid rectal growth.Birdem Med J 2015; 5(1) Supplement: 56-58

scholarly journals Juxtaglomerular Cell Tumor: Reviewing a Cryptic Cause of Surgically Correctable Hypertension

2019 ◽  
Vol 13 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Rafid Inam ◽  
Jason Gandhi ◽  
Gunjan Joshi ◽  
Noel L. Smith ◽  
Sardar Ali Khan
Keyword(s):  
Early Recognition ◽  
Rare Condition ◽  
Benign Neoplasm ◽  
Juxtaglomerular Apparatus ◽  
Cell Tumor ◽  
Surgical Removal ◽  
Juxtaglomerular Cell ◽  
Juxtaglomerular Cell Tumor ◽  
High Index Of Suspicion ◽  
The Impact

Juxtaglomerular cell tumor (JGCT), or reninoma, is a typically benign neoplasm generally affecting adolescents and young adults due to modified smooth muscle cells from the afferent arteriole of the juxtaglomerular apparatus. Patients experience symptoms related to hypertension and hypoka-lemia due to renin-secretion by the tumor. MRI, PET, CT, and renal vein catheterizations can be used to capture JGCTs, with laparoscopic ultrasonography being most cost-efec-tive. Surgical removal is the best option for management; electrolyte imbalances are a potential complication which may be assuaged via pre-surgical administration of aliskiren, a renin inhibitor. Considering the vast etiology for hypertension and rarity of JGCT, the diagnosing physician must have a high index of suspicion for JGCT. Early recognition and management can help prevent cardiovascular or pregnancy complications and fatalities, vascular invasion and metastasis, improve quality of life, and limit socioeconomic liabilities. Herein we review the epidemiology, genetics, histopathol-ogy, clinical presentation, and management of this rare condition. The impact of genetics on prognosis warrant further research.

scholarly journals Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
D. W. V. N. Dissanayaka ◽  
D. K. B. Dassanayaka ◽  
P. R. Jayasooriya
Keyword(s):  
Case Report ◽  
Family History ◽  
Autosomal Dominant ◽  
Rare Condition ◽  
Similar Type ◽  
Skin Tumours ◽  
Autosomal Dominant Pattern ◽  
Histopathological Evaluation ◽  
History Of ◽  
Nodular Lesions

Trichoepitheliomas (TE) are benign skin tumours of the pilosebaceous apocrine unit with follicular differentiation. Multiple familial trichoepithelioma (MFT) is a considerably rare condition inherited in an autosomal dominant pattern. We present a case of a 15-year-old male who presented with multiple papulo-nodular lesions in the central face and a family history of a similar type of lesions from his mother. Significance of consideration of various clinical differential diagnoses with serious pathological outcomes, strategies followed in the diagnosis including histopathological evaluation aided by immunohistochemical investigations, and subsequent challenges that may be faced in the management of MFT in light of the presentation with multiple facial papules are documented in this case report.

scholarly journals Progressive Nodular Histiocytosis: Report of a Case and Review of the Literature

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Numbereye Numbere ◽  
Tatsiana Pukhalskaya ◽  
Blythe Bowman ◽  
Katelynn Campbell ◽  
Bruce Smoller
Keyword(s):  
Plasma Cells ◽  
Clinical Presentation ◽  
Rare Condition ◽  
Giant Cells ◽  
Minor Admixture ◽  
Microscopic Features ◽  
Intralesional Injections ◽  
Nodular Lesions ◽  
Dermal Infiltrate ◽  
A Minor

Progressive nodular histiocytosis (PNH) is a rare condition characterized by progressive eruption of multiple yellowish-brown papules and nodules on the skin and mucous membranes. We present the case of a 37-year-old Caucasian man with gradually increased appearance of nodular lesions on the forehead and right temple. These lesions were initially diagnosed as xanthomas and did not respond to intralesional injections of triamcinolone. Additional biopsy revealed an intense dermal infiltrate of foamy mononuclear epithelioid cells with a minor admixture of plasma cells, lymphocytes, and scattered multinucleated giant cells. On immunohistochemical staining, the lesional cells were positive for CD163 and CD68 and negative for CD1a, thus confirming a mononuclear-macrophage lineage. The clinical presentation and the histological impression lead to the diagnosis of PNH. This condition could be challenging, mimicking microscopically similar lesions of the non-Langerhans cell histiocytosis group. Although uncommon, PNH stands out due to its clinical and microscopic features and should be taken into consideration in the differential diagnosis of cutaneous histiocytoses.

scholarly journals Nodular Oncocytic Hyperplasia of Bilateral Parotid Glands With Parapharyngeal Space Extension

2020 ◽  
pp. 014556132097378
Author(s):  
Chuan-Jen Hung ◽  
Yu-Hsi Liu ◽  
Jia-Bin Liao
Keyword(s):  
Salivary Glands ◽  
Parapharyngeal Space ◽  
Rare Condition ◽  
Benign Neoplasm ◽  
Parotid Glands ◽  
Transcervical Approach ◽  
Space Extension ◽  
Parapharyngeal Tumors ◽  
Total Parotidectomy

Oncocytic tumors comprise a group of rare benign neoplasm of salivary glands, accounting for less than 1% of all salivary gland tumors. Nodular oncocytic hyperplasia characterized by multiple unencapsulated oncocytic nodules in the salivary glands is an extremely rare condition. We report a case of bilateral nodular oncocytic hyperplasia of parotid glands with parapharyngeal space extension in an 80-year-old woman whose initial presentation was recurrent parotitis. Our case may be the first report of nodular oncocytic hyperplasia in the parapharyngeal space, arising from the parotid gland. The patient underwent total parotidectomy and excision of parapharyngeal tumors using a transparotid transcervical approach, and at the 2-year follow-up, no evidence of recurrence was found.

scholarly journals Pigmented Nodular Basal Cell Carcinomas in Differential Diagnosis with Nodular Melanomas: Confocal Microscopy as a Reliable Tool forIn VivoHistologic Diagnosis

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Alice Casari ◽  
Giovanni Pellacani ◽  
Stefania Seidenari ◽  
Anna Maria Cesinaro ◽  
Francesca Beretti ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Confocal Microscopy ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Imaging Technique ◽  
Skin Tumors ◽  
Basal Cell Carcinomas ◽  
Nodular Lesions

Nodular basal cell carcinoma, especially when pigmented, can be in differential diagnosis with nodular melanomas, clinically and dermoscopically. Reflectance confocal microscopy is a relatively new imaging technique that permits to evaluate in vivo skin tumors with a nearly histological resolution. Here, we present four cases of challenging nodular lesions where confocal microscopy was able to clarify the diagnosis.

An adrenocortical oncocytoma with unusual mitochondrial inclusions and cytoplasmic crystals

1994 ◽  
Vol 52 ◽  
pp. 250-251
Author(s):  
W.T. Gunning ◽  
G.D. Haselhuhn ◽  
E.R. Phillips ◽  
S.H. Selman
Keyword(s):  
Adrenal Gland ◽  
Salivary Glands ◽  
Mitotic Activity ◽  
Diagnostic Criteria ◽  
Vascular Invasion ◽  
Benign Neoplasm ◽  
Benign Tumors ◽  
Nuclear Morphology ◽  
Case Presentation ◽  
Microscopic Evidence

Within the last few years, adrenal cortical tumors with features concordant with the diagnostic criteria attributed to oncocytomas have been reported. To date, only nine reported cases exist in the literature. This report is the tenth case presentation of a presumptively benign neoplasm of the adrenal gland with a rare differentiation. Oncocytomas are well recognized benign tumors of the thyroid, parathyroid, and salivary glands and of the kidney. Other organs also give rise to these types of tumors, however with less frequency than the former sites. The characteristics generally used to classify a tumor as an oncocytoma include the following criteria: the tumor is 1) usually a solitary circumscribed mass with no gross nor microscopic evidence of metastasis (no tissue nor vascular invasion), 2) fairly bland in terms of mitotic activity and nuclear morphology, and 3) composed of large eosinophillic cells in which the cytoplasm is packed full of mitochondria (Figure 1).

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