scholarly journals Design and implementation of a less invasive gastrostimulator

Author(s):  
Laurent Lonys ◽  
Anne Vanhoestenberghe ◽  
Vincent Huberty ◽  
Martin Hiernaux ◽  
Nicolas Cauche ◽  
...  

Gastrointestinal stimulator implants have recently shown positive results in helping obese patients lose weight. However, to place the implant, the patient currently needs to undergo an invasive surgical procedure. Our team is aiming for a less invasive procedure to stimulate the stomach with a gastrostimulator. Attempts covered fully endoscopic implantation and, more recently, we have focussed on a single incision laparoscopic procedure. Whatever the chosen implantation solution, the electronic design of the implant system shares many challenges. This paper covers the work achieved to meet these.

2013 ◽  
Vol 271 (5) ◽  
pp. 1149-1155 ◽  
Author(s):  
Ai Kawamoto ◽  
Yukio Katori ◽  
Yohei Honkura ◽  
Risako Kakuta ◽  
Kenjiro Higashi ◽  
...  

2011 ◽  
Vol 31 (10) ◽  
pp. 1986-1998 ◽  
Author(s):  
Paolo Zanotti-Fregonara ◽  
Kewei Chen ◽  
Jeih-San Liow ◽  
Masahiro Fujita ◽  
Robert B Innis

Quantitative positron emission tomography (PET) brain studies often require that the input function be measured, typically via arterial cannulation. Image-derived input function (IDIF) is an elegant and attractive noninvasive alternative to arterial sampling. However, IDIF is also a very challenging technique associated with several problems that must be overcome before it can be successfully implemented in clinical practice. As a result, IDIF is rarely used as a tool to reduce invasiveness in patients. The aim of the present review was to identify the methodological problems that hinder widespread use of IDIF in PET brain studies. We conclude that IDIF can be successfully implemented only with a minority of PET tracers. Even in those cases, it only rarely translates into a less-invasive procedure for the patient. Finally, we discuss some possible alternative methods for obtaining less-invasive input function.


1993 ◽  
Vol 109 (4) ◽  
pp. 748-752
Author(s):  
Tsuyako Fukuyama ◽  
Toshiro Umezaki ◽  
Takemoto Shin

We previously reported on evoked potentials elicited by electrical stimulation of the superior laryngeal nerve at an appropriate site on the dural surface as a reflection of activities in the brain stem and cortex in anesthetized cats. This evoked potential was called the laryngeal sensory evoked potential (LSEP). In this study we attempted to establish a less invasive procedure for measuring LSEP. The procedures were recording on the scalp using chloride-coated silver disk electrodes and stimulation by insertion of a bipolar platinum hooked wire electrode into the laryngeal mucosa. Evoked potentials could be detected using these less invasive procedures. The response morphologies and relative timing of LSEP components were quite similar for each method in a given cat. However, the amplitudes were slightly lower and the latencies were slightly prolonged with the less invasive techniques. These results suggest that this LSEP method might be applicable to human beings as a noninvasive method for evaluating the function of the laryngeal sensory pathway


Author(s):  
Muhammad Azeemuddin ◽  
Tanveer Ul Haq ◽  
Shahmeer Khan ◽  
Raza Sayani ◽  
Ayesha Shoukat Hussain ◽  
...  

Abstract Management of endogenous Cushing syndrome is based on its aetiology. Increased Adrenocorticotropic Hormone (ACTH) levels are the most common cause of this disorder and, therefore, it is critical to determine the source of ACTH before further management. Dynamic post contrast MRI is currently the most common investigation implied to diagnose pituitary adenoma; however, it comes with the drawback of low specificity and high false positive results. Inferior petrosal sinus sampling (IPSS) is an established invasive procedure performed to differentiate central versus peripheral source of ACTH which, in turn, results in hypercortesolaemia. This is a series of 14 patients who underwent IPSS at the Department of Radiology, Aga Khan University Hospital, Karachi, from January 2006 to December 2018. The case series emphasises the role of IPSS in the management of ACTH-dependent Cushing syndrome and combined efficacy of Dynamic post-contrast MRI and the procedure under focus. Continuous....


2017 ◽  
Vol 103 (2) ◽  
pp. e203-e206 ◽  
Author(s):  
Feng Gao ◽  
Jing Chen ◽  
Qian Zeng ◽  
Fangming Lin

2016 ◽  
Vol 72 (11) ◽  
pp. 677-680
Author(s):  
Michał Gnus ◽  
Kornel Ratajczak ◽  
Jarosław Mendrek

The increase in the occurrence of LDA in cows stems from the increase in the milk yields from cows. The treatment is based on a surgical method, and its effectiveness has an economic effect. The article below presents progress made in identifying the nature of LDA over the last 50 years. Also included is a critical assessment of contemporary and accepted LDA treatments. The surgical procedure has two aims: repositioning and fastening the abomasum directly to the abdominal wall, which prevents the recurrence of this disease. Over the course of the last 50 years LDA surgery has evolved from the laparotomy method to laparoscopy. This latest method has become more readily available and popular. It is characterized by less invasive surgical techniques and faster recovery, as well as lowering the cost of treatment. However, laparoscopy cannot treat every case. Complications or technical difficulties during an operation sometimes force doctors to finish the surgery by laparotomy. To avoid the problem of having to change the technique during the operation, doctors should choose the most appropriate method for each particular case.


2020 ◽  
Author(s):  
Hussein Taqi

The surgical myomectomy for hypertrophied myocardium in patients with HOCM is a well-established and evidence-based treatment modality. However, with the drawback of exposing the patient to major surgery and prolonged post-operative periods, cardiologists together with their surgical peers found the advent of a potentially less invasive procedure. This has been accomplished by the installation of alcohol through the coronary arteries in order to shrink the diseased and hypertrophied muscle area with an aim to alleviate the symptoms in the first instance if not completely curing the pathology as an endeavor goal. Nevertheless, with this invention, a few complications have started to emerge. The main drawback was heart block, which could require permanent pacemaker insertion in most of the cases. In the interim, there is no clear pathway or guideline to decide which treatment option would be the best, and there is no certain inclusion or exclusion criteria incorporate patients who can undergo either one of the modalities. In this review, four studies were scrutinized to investigate the major consequences of each route, especially focusing on the proportion of complete heart block. Also, the role of MRI in the delineation of the resected area either surgically or by alcohol administration is studied in detail. After reviewing these articles, it has been concluded that despite alcohol septal ablation being less invasive approach, surgical therapy remains the preferred treatment modality and it is preferred treatment modality and so far, it is the gold standard option in the management of hypertrophic obstructive cardiomyopathy. Nevertheless, it could not be overlooked the lack of strong RCTS in such area which could be one of the main points that future trialists need to consider.


2015 ◽  
Vol 6 (4) ◽  
pp. 131-137
Author(s):  
Vivek Srivastava ◽  
Narendra Nath Das ◽  
Anand Kumar ◽  
Mumtaz Ahmad Ansari ◽  
◽  
...  

2005 ◽  
Vol 64 (1) ◽  
Author(s):  
Andrea Cuppini ◽  
Paola Matteini

The recent ATP III classification defines metabolic syndrome as including ≥3 of the following characteristics: abdominal adiposity, atherogenic dyslipidemia, high blood pressure, and insulin resistance. In these patients the visceral fat may produce inflammatory cytochines that may account for an enhanced cardiovascular risk. The treatment of obese patients is complex and often ineffective: patients may initially reduce weight but subsequently regain or even increase it, according to the socalled “yo-yo syndrome”. Given the difficulties of treatment of patients with incresed BMI, visceral adiposity, or metabolic syndrome, a multidisciplinary approach to these patients may yield more frequent positive results. The different strategies that may be applied, in varying mix targeted to the individual patient, include diet, drugs, educational and psychological support and, in few selected cases, surgery.


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