scholarly journals Advances in exercise rehabilitation for patients with Lower Extremity Peripheral Artery Disease

2016 ◽  
Vol 86 (1-2) ◽  
Author(s):  
Marco Ambrosetti

Patients with Lower Extremity Peripheral Artery Disease (LEPAD) have been recently identified as target groups for structured Cardiac Prevention and Rehabilitation (CPR) programs, whose core components and intervention goals are now well recognized. Historically, exercise training (ET) programs have been employed for the treatment of LEPAD with typical intermittent claudication, and several meta-analysis documented improvements in walking distances of enrolled patients. Both in American and European guidelines, a frequency of at least 3 sessions per week and program duration of 12 weeks were judged as optimal, while recommended sessions lengths were 30-45 minutes and 30-60 minutes respectively. Among emerging aspects in the field of LEPAD rehabilitation, 1) the extended role of CPR programs in stages other than that of intermittent claudication, 2) an updated identification of predictors of poor outcome after ET, 3) the attributable effect of exercise on global cardio-respiratory fitness in LEPAD, 4) the combination of ET and invasive measures for advanced stages of LEPAD, and 5) the role of community walking programs have been discussed.

2020 ◽  
Vol 50 (6) ◽  
pp. 1291-1298
Author(s):  
Mira Merashli ◽  
Tommaso Bucci ◽  
Daniele Pastori ◽  
Pasquale Pignatelli ◽  
Vincenzo Marottoli ◽  
...  

2015 ◽  
Vol 30 (5) ◽  
pp. 525-535 ◽  
Author(s):  
Subhash Banerjee ◽  
Karan Sarode ◽  
Ariel Vinas ◽  
Avantika Banerjee ◽  
Atif Mohammad ◽  
...  

2018 ◽  
Vol 269 ◽  
pp. 292-297 ◽  
Author(s):  
Eliano P. Navarese ◽  
Bernhard Wernly ◽  
Michael Lichtenauer ◽  
Aniela M. Petrescu ◽  
Michalina Kołodziejczak ◽  
...  

BMC Surgery ◽  
2012 ◽  
Vol 12 (Suppl 1) ◽  
pp. S13 ◽  
Author(s):  
Anna Franzone ◽  
Marco Ferrone ◽  
Giuseppe Carotenuto ◽  
Andreina Carbone ◽  
Laura Scudiero ◽  
...  

2021 ◽  
Vol 2 (2) ◽  
pp. 1-3
Author(s):  
Novi Kurnianingsih

Peripheral artery disease (PAD) is a chronic occlusive disease of arteries in the lower extremity due to atheroscle- rosis. PAD can lead to intermittent claudication, which is weakness or pain with walking alleviated with rest. Until now, the awareness of the public and medical personnel regarding PAD is still not as high as the alertness of coronary disorders. This editorial will focus on diagnosing and treating PAD focused on lower extremity artery disease (LEAD).


Vascular ◽  
2021 ◽  
pp. 170853812110183
Author(s):  
Arda Aybars Pala ◽  
Yusuf Salim Urcun

Objectives Triglyceride-glucose index (TyG index), which is defined as the simple and novel marker of insulin resistance, is becoming increasingly important as a promising predictive marker for atherosclerotic diseases. Chronic limb-threatening ischemia is defined as the most advanced stage of the lower extremity peripheral artery disease, whose main cause is atherosclerosis and is associated in this respect with amputation, impaired quality of life, and mortality. The main purpose of the present study was to investigate the relation between the calculated TyG index values and chronic limb-threatening ischemia development. Methods A total of 296 patients who were diagnosed with lower extremity peripheral artery disease in our outpatient clinic between October 2018 and October 2020 were included in this study retrospectively. Two groups were formed by clinically staging the patients according to Rutherford Classification. Patients who did not develop chronic limb-threatening ischemia were classified as “Group 1” ( n = 224) and those who developed were classified as “Group 2” ( n = 72). Results The mean TyG index values that were calculated in Group 2 were significantly higher than in Group 1 (9.27 ± 0.31 vs. 9.00 ± 0.34, p < 0.001). In the multivariate logistic regression analysis conducted to determine the predictors of chronic limb-threatening ischemia development, C-reactive protein (OR [Odds Ratio]: 1.220, 95% CI [confidence interval]: 1.092–1.363, p < 0.001), high-density lipoprotein cholesterol (OR: 0.775, 95% CI: 0.715–0.839, p < 0.001) and TyG index (OR: 5.796, 95% CI: 2.050–16.382, p = 0.001) were identified as independent predictors. Receiver operating characteristic analysis revealed that the cut-off value of TyG index was 9.13 (area under the curve: 0.721, p < 0.001) with 70.8% sensitivity and 65.2% specificity. The TyG index was significantly correlated with Rutherford category, high-density lipoprotein cholesterol and mean platelet volume. Conclusions Chronic limb-threatening ischemia development may be predicted with the TyG index value, which is calculated easily from routine biochemical parameters, in patients diagnosed with lower extremity peripheral artery disease.


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