scholarly journals Current strategies for the treatment of aneurysmal bone cysts

2015 ◽  
Vol 7 (4) ◽  
Author(s):  
Panagiotis Tsagozis ◽  
Otte Brosjö
Keyword(s):  
Open Surgery ◽  
Early Adulthood ◽  
Surgical Excision ◽  
Functional Results ◽  
Treatment Modalities ◽  
Bone Cysts ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Aneurysmal Bone Cysts ◽  
Good Local Control

Aneurysmal bone cysts are benign bone tumors that usually present in childhood and early adulthood. They usually manifest as expansile osteolytic lesions with a varying potential to be locally aggressive. Since their first description in 1942, a variety of treatment methods has been proposed. Traditionally, these tumors were treated with open surgery. Either intralesional surgical procedures or <em>en</em> <em>bloc</em> excisions have been described. Furthermore, a variety of chemical or physical adjuvants has been utilized in order to reduce the risk for local recurrence after excision. Currently, there is a shift to more minimally invasive procedures in order to avoid the complications of open surgical excision. Good results have been reported during percutaneous surgery, or the use of embolization. Recently, sclerotherapy has emerged as a promising treatment, showing effective consolidation of the lesions and functional results that appear to be superior to the ones of open surgery. Lastly, non-invasive treatment, such as pharmaceutical intervention with denosumab or bisphosphonates has been reported to be effective in the management of the disease. Radiotherapy has also been shown to confer good local control, either alone or in conjunction to other treatment modalities, but is associated with serious adverse effects. Here, we review the current literature on the methods of treatment of aneurysmal bone cysts. The indication for each type of treatment along reported outcome of the intervention, as well as potential complications are systematically presented. Our review aims to increase awareness of the different treatment modalities and facilitate decision-making regarding each individual patient.

Contemporary Treatment for Central Serous Chorioretinopathy

2021 ◽  
Author(s):  
Mitova D
Keyword(s):  
Subretinal Fluid ◽  
Functional Results ◽  
Clinical Results ◽  
Long Term Results ◽  
Nanosecond Laser ◽  
Success Rates ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Short And Long Term

Aim: To study the short-and long-term results of 2RT nanosecond laser treatment for CSC. To compare clinical results with those with AntiVEGF. Methods: Nanosecond laser (2RT, Ellex) was used. Patients were followed by BCVA, FAF, OCT, Angio-OCT. Results: 90% of the patient treated with 2RT had improvement of visual acuity and contrast sensitivity. 19 % [1] patients showed no improvement. 81% of the 2RT treated patients had total resorbtion of subretinal fluid against 60% treated with AntiVEGF. Functional results correlated with the atrophy of RPE in the macula. 46% (19 patients) had resolution on the first month, 23% [2]-on the third and 12% [3]-on the sixth month. The time of resolution shows no relation to the baseline pigment epithelial atrophy. Four patients presented with a recurrency of the disease in the follow-up period. 19% [1] were non responders. 60% of AntiVEGF treated eyes were responders and 40% were non responders. Those who responded to treatment needed between 3 and 10 injections. Conclusion: 2 RT is a non-invasive treatment modality with no adverse effects and high success rates.

scholarly journals Aneurysmal Bone Cyst Involving the Pisiform: A Case Report

Hand ◽  
2016 ◽  
Vol 12 (5) ◽  
pp. NP55-NP57
Author(s):  
Eduardo P. Zancolli ◽  
John M. Ranson ◽  
Sunil M. Thirkannad
Keyword(s):  
Bone Cyst ◽  
Pathologic Fracture ◽  
Surgical Excision ◽  
Subsequent Treatment ◽  
Uneventful Recovery ◽  
Bone Cysts ◽  
Primary Bone Tumors ◽  
Ulnar Nerve Compression ◽  
Left Hand ◽  
Aneurysmal Bone Cysts

Background: Aneurysmal bone cysts are an uncommon form of benign primary bone tumors; affection of the hand is very rare. Methods: A rigorous review of the literature showed that this type of tumor has not previously been described in the pisiform. In this article, we report the occurrence of an aneurysmal bone tumor in the pisiform of the left hand of a 19-year-old male. Results: This tumor was successfully treated through surgical excision with an uneventful recovery. We describe the process behind the diagnosis of the lesion and the subsequent treatment in an attempt to highlight the rare but possible occurrence of aneurysmal bone cysts in the pisiform. Conclusion: Appropriate treatment of aneurysmal bone cysts in this location is required, due to the anatomical nature of the pisiform itself with the risks of pathologic fracture and ulnar nerve compression.

Recent Trends in the Management of Aneurysmal Bone Cyst

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Rafeek Ahmed Sadek ◽  
Ashraf Mohamed El Seddawy ◽  
Hussein Mohamed Ahmed Gomaa
Keyword(s):  
Aneurysmal Bone Cyst ◽  
Healing Rate ◽  
Bone Cyst ◽  
Case Series ◽  
Treatment Modalities ◽  
Thin Wall ◽  
Bone Cysts ◽  
Large Hole ◽  
Aneurysmal Bone Cysts ◽  
Complications Rate

Abstract Background Aneurysmal bone cysts (ABCs), were first described by Drs. Jaffe and Lichenstein in 1942 when they described pelvic and spine lesions that when exposing the lesion and opening in to its thin wall, the surgeon was immediately confronted by a large hole containing much fluid blood. Aim of the Work To describe the efficacy of new line treatment modalities of (Aneurysmal Bone Cysts) compared to conventional lines of management regarding the: • Long term outcomes and healing rate. • Recurrence rates. • Complications after therapy. Patients and Methods Criteria for considering studies for this review: • Types of the studies: published observational analytical studies (case-control_ case-series _ RCT or cohort studies) which studied the efficiency of new lines in the management of aneurysmal bone cyst. • Types of participants: participants were children and young age (below the age of 50 yrs) with a diagnosis of aneurysmal bone cyst. • Types of interventions: drugs like (Bisphosphonate or denosumab) were administered for a time determined by the case improvement, or minimally invasive techniques like (cryosurgery or curopsy) was done. Results Through the results of our study that compared between these recent modalities according to healing, recurrence, and complications rate; we are able to say that recent strategies have a high rate of healing ranges from 78.57% with bisphosphonate to 100% with doxycycline and cryotherapy. Conclusion There are recent evolving trends in the management of ABC other than the classic ways of management, they are less invasive, have less recurrence rate reaches to 0 % like with bisphosphonate, less complications rate as well reaches to 0 % like with doxycycline and bisphosphonate, high healing rate reaches to 100 % like with doxycycline and taking in consideration how to handle cases of ABC that classic way of management can’t handle like spinal ABC.

scholarly journals Utility of Photodynamic Therapy in Dentistry: Current Concepts

2020 ◽  
Vol 8 (2) ◽  
pp. 43
Author(s):  
Anette Stájer ◽  
Szilvia Kajári ◽  
Márió Gajdács ◽  
Aima Musah-Eroje ◽  
Zoltán Baráth
Keyword(s):  
Photodynamic Therapy ◽  
Clinical Success ◽  
Maxillofacial Surgery ◽  
Treatment Method ◽  
Treatment Modalities ◽  
Oral And Maxillofacial Surgery ◽  
Invasive Treatment ◽  
Advantages And Disadvantages ◽  
Non Invasive ◽  
Wide Range

The significant growth in scientific and technological advancements within the field of dentistry has resulted in a wide range of novel treatment modalities for dentists to use. Photodynamic therapy (PDT) is an emerging, non-invasive treatment method, involving photosensitizers, light of a specific wavelength and the generation of singlet oxygen and reactive oxygen species (ROS) to eliminate unwanted eukaryotic cells (e.g., malignancies in the oral cavity) or pathogenic microorganisms. The aim of this review article is to summarize the history, general concepts, advantages and disadvantages of PDT and to provide examples for current indications of PDT in various subspecialties of dentistry (oral and maxillofacial surgery, oral medicine, endodontics, preventive dentistry, periodontology and implantology), in addition to presenting some images from our own experiences about the clinical success with PDT.

Treatment of temporal artery pseudoaneurysms

Vascular ◽  
2013 ◽  
Vol 22 (4) ◽  
pp. 274-279 ◽  
Author(s):  
Irene Thomassen ◽  
Elisabeth G Klompenhouwer ◽  
Edith M Willigendael ◽  
Joep AW Teijink
Keyword(s):  
Superficial Temporal Artery ◽  
Surgical Excision ◽  
Temporal Artery ◽  
Primary Treatment ◽  
Treatment Modalities ◽  
Diagnostic Process ◽  
Thrombin Injection ◽  
Invasive Treatment ◽  
Artery Pseudoaneurysm ◽  
Primary Treatment Modality

Purpose To give an overview of the etiology and diagnostic process of superficial temporal artery pseudoaneurysms and to evaluate different treatment modalities. Basic methods PubMed was used for searching multiple databases for relevant clinical studies. Principal findings A total of 62 studies were included, harboring 82 patients. Surgical excision is the most frequently described treatment, but less invasive treatment modalities as coiling and thrombin injections are gaining popularity. Surgical treatment was successful in all cases (67/67). Endovascular treatment was successful in 69% (9/13); the five cases treated with thrombin injection were all successful. Complementary, a description of our experience with thrombin injection is given. Conclusions Limited evidence of minimal invasive treatment for superficial temporal artery pseudoaneurysm is available. Based on this review combined with our limited experience, we suggest thrombin injections to be considered as the future primary treatment modality. In the case of unsuccessful exclusion of the aneurysm, surgical excision can be performed.

scholarly journals Outcome of non-invasive treatment modalities on back pain: an evidence-based review

2005 ◽  
Vol 15 (S1) ◽  
pp. S64-S81 ◽  
Author(s):  
Maurits W. van Tulder ◽  
Bart Koes ◽  
Antti Malmivaara
Keyword(s):  
Back Pain ◽  
Treatment Modalities ◽  
Evidence Based ◽  
Invasive Treatment ◽  
Non Invasive

Aneurysmal Bone Cysts of the Jaws

1994 ◽  
Vol 103 (2) ◽  
pp. 164-165 ◽  
Author(s):  
Matthew Kershisnik ◽  
John G. Batsakis
Keyword(s):  
Surgical Excision ◽  
Bone Cysts ◽  
Recurrence Rates ◽  
Osseous Lesion ◽  
Aneurysmal Bone Cysts

Aneurysmal bone cysts of the jaws are histologically the same as those found in the more usual appendicular sites for this lesion. They may be primary or secondary (associated with another definable osseous lesion) and have a 2:1 or 3:1 predilection for the mandible over the maxilla. Curettage is associated with relatively high recurrence rates, while surgical excision, with negative margins, of primary lesions markedly reduces this incidence.

Radiologic Evaluation of Bone Incorporation of Strut Allografting in Bone Defects After Curettage of Benign Bone Tumors

1997 ◽  
Vol 01 (02) ◽  
pp. 141-148
Author(s):  
H.-N. Shih ◽  
Y.-J. Chen ◽  
K.-Y. Hsu ◽  
T.-J. Huang ◽  
C.-F. Tan ◽  
...  
Keyword(s):  
Functional Results ◽  
Long Bone ◽  
Bone Cysts ◽  
Giant Cell Tumors ◽  
Intralesional Curettage ◽  
Radiographic Appearance ◽  
Radiologic Evaluation ◽  
Pathologic Fractures ◽  
Aneurysmal Bone Cysts

Large osseous defects have long been a challenge to the reconstructive surgeon. In a series of 104 patients (average age of 26 years; range, 11–60 years) with space occupying lesions of the long bone, we implanted deep-frozen (-70° C) cortical strut allografts into the defects after intralesional curettage. Because of the relatively few published reports on the radiographic appearance of the postoperative course of bone grafting healing, this study was done to investigate the course of radiographic change. This series included 36 fibrous dysplasias, 29 unicameral bone cysts, 22 giant cell tumors, 12 aneurysmal bone cysts, 3 benign fibrous histiocytomas and 2 ossifying fibromas. Fifty-six patients had pathologic fractures. The mean volume of the defect after curettage was 210 ml (range, 56–460 ml). All the patients were followed up for an average of 4 years (range, 2–6 years). At follow-up, good or excellent functional results were found in 97% of the patients (101/104). The radiographs demonstrated complete incorporation of the allogeneic implant and new bone formation in the cavity in 83% of the patients (86/104) (using a semiquantitative method). All pathologic fractures healed. There was no local recurrence or fracture of the cortical graft. There were no other serious complications except for one avascular necrosis of the femoral head. The process of allograft incorporation was similar to that of fresh autograft, though remodeling was rather delayed.

scholarly journals Long term assessment of intralipotherapy in Madelung’s disease

2014 ◽  
Vol 47 (03) ◽  
pp. 427-431 ◽  
Author(s):  
Silvia Scevola ◽  
Giovanni Nicoletti ◽  
Antonino Neri ◽  
Angela Faga
Keyword(s):  
Palliative Treatment ◽  
Surgical Excision ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Madelung's Disease ◽  
Madelung’S Disease ◽  
Average Size ◽  
Head Neck

ABSTRACTMadelung’s disease is characterised by multiple symmetric abnormal fat masses in the head, neck and upper limbs. Surgical excision or liposuction is the only realistic available option, although palliative in nature. The serial intralipotherapy with phosphatidylcholine/deoxycholate has been proposed as a non-invasive treatment of Madelung’s disease. The authors used serial intralipotherapy with phosphatidylcholine/deoxycholate in two patients affected by Madelung’s disease. Three injections per lesion per patient were performed with 1 month’s interval. Pre- and 6 months’ post-treatment dimensions were assessed with ultrasound scan and patients were observed along a 5 years’ clinical follow-up. A 42.5% average size reduction was reported in all treated lesions. About 33% recurrence rate was observed in the 5 years’ follow-up. We confirm the efficacy of intralipotherapy in the non-invasive palliative treatment of Madelung’s disease, as a valid option to reduce the volume and limit the growth of the pathological adipose masses.

ANEURYSMAL BONE CYST OF THE HAND: A REPORT OF FOUR CASES

Hand Surgery ◽  
2006 ◽  
Vol 11 (01n02) ◽  
pp. 35-41 ◽  
Author(s):  
Kerem Başarir ◽  
Yener Saǧlik ◽  
Yusuf Yildiz ◽  
Engyn Tezen
Keyword(s):  
Aneurysmal Bone Cyst ◽  
Bone Grafting ◽  
Bone Cyst ◽  
Local Therapy ◽  
Treatment Modalities ◽  
Bone Cysts ◽  
Total Excision ◽  
Benign Lesions ◽  
Recurrence Rates ◽  
Aneurysmal Bone Cysts

Aneurysmal bone cysts are benign lesions that rarely occur in the bones of the hand. Curettage and bone grafting are the most common treatment modalities performed considering the possible functional loss after total excision. Four cases of aneurysmal bone cyst of the hand were identified. Three out of four cases were treated initially with curettage and bone grafting alone without any other local therapy. One had total excision of the lesion. There were two recurrences in the curettage group. Both were treated with excision and followed up for a minimum of 12 months. Curettage alone was associated with high recurrence rates. Total excision of the lesion was the most successful procedure employed. In view of the high recurrence rates following curettage alone and non-neoplastic nature of the lesion, adjuvant treatment modalities such as cryosurgery, electric cauterisation should be considered for initial treatment of ABC. Resection should be preserved for recurrent cases.

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