scholarly journals Long term assessment of intralipotherapy in Madelung’s disease

2014 ◽  
Vol 47 (03) ◽  
pp. 427-431 ◽  
Author(s):  
Silvia Scevola ◽  
Giovanni Nicoletti ◽  
Antonino Neri ◽  
Angela Faga
Keyword(s):  
Palliative Treatment ◽  
Surgical Excision ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Madelung's Disease ◽  
Madelung’S Disease ◽  
Average Size ◽  
Head Neck

ABSTRACTMadelung’s disease is characterised by multiple symmetric abnormal fat masses in the head, neck and upper limbs. Surgical excision or liposuction is the only realistic available option, although palliative in nature. The serial intralipotherapy with phosphatidylcholine/deoxycholate has been proposed as a non-invasive treatment of Madelung’s disease. The authors used serial intralipotherapy with phosphatidylcholine/deoxycholate in two patients affected by Madelung’s disease. Three injections per lesion per patient were performed with 1 month’s interval. Pre- and 6 months’ post-treatment dimensions were assessed with ultrasound scan and patients were observed along a 5 years’ clinical follow-up. A 42.5% average size reduction was reported in all treated lesions. About 33% recurrence rate was observed in the 5 years’ follow-up. We confirm the efficacy of intralipotherapy in the non-invasive palliative treatment of Madelung’s disease, as a valid option to reduce the volume and limit the growth of the pathological adipose masses.

Long-term evaluation of extracorporeal shock wave lithotripsy in the treatment of salivary stones

2007 ◽  
Vol 122 (1) ◽  
pp. 65-71 ◽  
Author(s):  
S Schmitz ◽  
P Zengel ◽  
I Alvir ◽  
M Andratschke ◽  
A Berghaus ◽  
...  
Keyword(s):  
Shock Wave ◽  
Extracorporeal Shock Wave Lithotripsy ◽  
Shock Wave Lithotripsy ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Extracorporeal Shock Wave ◽  
Stone Treatment ◽  
Term Evaluation ◽  
Average Size

AbstractExtracorporeal shock wave lithotripsy is a rather new therapeutical method in the treatment of sialolithiasis. The objective was to evaluate retrospectively the results of the extracorporeal shock wave lithotripsy therapy performed with a Minilith SL 1 lithotripter on 167 out-patients with symptomatic stones (average size 5.94 mm) of the salivary glands over an observation period of seven years. A successful treatment with total stone disintegration was achieved in 51 (31 per cent) patients. In 92 (55 per cent) patients treatment was partially successful, with disappearance of the symptoms but a sonographically still identifiable stone. Treatment failure occurred in 24 (14 per cent) patients who then underwent surgery. The mean follow-up period was 35.6 months (minimum three, maximum 83), after which 83.2 per cent of the initially successfully treated patients were still free of symptoms.Therefore, extracorporeal shock wave lithotripsy, as a non-invasive treatment alternative with few side effects, is an efficient technique for the therapy of sialolithiasis in selected patients.

scholarly journals Single stage surgical excision for vascular malformation without any pre-operative adjuvant therapy: our experience regarding case selection in 20 patients

2018 ◽  
Vol 6 (1) ◽  
pp. 271 ◽  
Author(s):  
Narendra G. Naik ◽  
Sangram Karandikar
Keyword(s):  
Surgical Treatment ◽  
Vascular Malformation ◽  
Vascular Malformations ◽  
Single Stage ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Primary Surgery ◽  
Case Selection

Background: Vascular malformations generally present in young population. The patients or their guardians seek treatment for alleviation of functional and/or cosmetic disfigurement. Non-invasive techniques with or without surgery are available, however surgical treatment has been found to be most definitive modality of treatment in selected cases of vascular malformations. In this article, we are presenting our experience of single stage partial/total excision of vascular malformation of various types, at different location on body without any adjuvant treatment with emphasis on the post-operative outcome. The aim of the study was to evaluate criteria for case selection, freedom from symptoms, cosmetic outcome, functional improvement, long term post-operative result and quality of life.Methods: This study was performed to assess outcome of surgical treatment for 20 patients of vascular malformation. Fourteen were offered primary surgery and 6 out of 20 had received prior non-invasive treatment. The post-operative follow-up period was minimum 6 months and maximum for 4 years.Results: The patients who underwent primary surgery were more satisfied than those who had received non-invasive treatment before surgery. This was because of satisfactory cosmetic outcome, minimal post-operative pain of short duration, no post-operative residual wound and minimal post-operative morbidity.Conclusions: For treatment of vascular malformations, surgery can be offered as the primary and only treatment modality in selected cases because of immediate resolution of mass, minimal complications, satisfactory functional outcome and acceptable cosmetic appearance. Also, this improved patient compliance and long term follow up.

scholarly journals Long-Term Follow-Up Results of Mechanical Wrist Traction as Non-Invasive Treatment for Carpal Tunnel Syndrome

2021 ◽  
Vol 12 ◽  
Author(s):  
Margreet Meems ◽  
Myrthe G. B. M. Boekhorst ◽  
Victor J. M. Pop
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Symptom Severity ◽  
Intervention Group ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Tunnel Syndrome ◽  
Mechanical Traction

Background: For patients with carpal tunnel syndrome (CTS), the only long-term effective treatment option is carpal tunnel release surgery. Up to one-third report recurrent symptoms, and 12% needs repeated surgery. This study aimed to evaluate the long-term effects of mechanical traction as a non-invasive treatment option for CTS compared to care as usual.Methods: Patients with electrodiagnostically confirmed CTS [N = 181; mean age, 58.1 (13.0) years; 67% women] were recruited from an outpatient neurology clinic in the Netherlands. Patients completed baseline questionnaires and randomized to the intervention group (12 treatments with mechanical traction, twice a week for 6 weeks) or care as usual. The primary clinical outcome measure was surgery during the 12-month follow-up. Secondly, we assessed symptom severity with the Boston Carpal Tunnel Questionnaire (BCTQ) at baseline and at the 12-month follow-up. Changes in CTS symptom severity between baseline and the 12-month follow-up were analyzed between groups using t-tests and a multiple linear regression analyses, adjusting for duration of complaints, age, gender, and symptom severity at baseline.Results: At the 12-month follow-up, 35 of 94 (37%) patients in the intervention group had surgery, compared to 38 of 87 (44%) in the care-as-usual group (χ12 = 0.78, p = 0.377). Symptom severity and functional status scores did not significantly differ between the intervention (n = 81) and care-as-usual group (n = 55) at follow-up. For patients who did not have surgery, BCTQ scores decreased significantly more from baseline to the 12-month follow-up in the intervention group (n = 53) compared to patients in the care-as-usual group (n = 25). For patients who did not have surgery, belonging to the intervention group and a higher BCTQ score at baseline were related to a greater decrease in BCTQ scores from baseline to the 12-month follow-up, as well as symptom severity and functional status.Conclusions: Mechanical traction is effective in reducing symptom severity compared to current conservative treatment options in standard care and can therefore benefit the large number of patients that prefer conservative treatment for CTS.Clinical Trial Registration: Clinical Trials NL44692.008.13. Registered 19 September 2013, https://clinicaltrials.gov/ct2/show/NCT01949493

scholarly journals Madelung’s disease: long-term follow-up

2019 ◽  
Vol 2019 (1) ◽  
Author(s):  
Motomu Suito ◽  
Takeshi Kitazawa ◽  
Ikkei Takashimizu ◽  
Tsuneko Ikeda
Keyword(s):  
Madelung's Disease ◽  
Madelung’S Disease ◽  
Long Term Follow Up

scholarly journals Clinical profile and management of pleomorphic adenoma of head neck: our experience

2019 ◽  
Vol 5 (6) ◽  
pp. 1615
Author(s):  
Rameshwar T. Pawar ◽  
Ashok Z. Nitnaware ◽  
Seema V. Patel ◽  
Tanvi S. Rekhade
Keyword(s):  
Pleomorphic Adenoma ◽  
Surgical Excision ◽  
Age Group ◽  
Medical College ◽  
Long Term Follow Up ◽  
Male Preponderance ◽  
The Common ◽  
Head Neck

<p class="abstract"><strong>Background:</strong> Pleomorphic adenoma constitutes one of the common salivary gland tumors. Our aim is to study the clinical presentation of pleomorphic adenoma, preoperative and postoperative histopathological findings and management of tumors.</p><p class="abstract"><strong>Methods:</strong> A retrospective study of 43 patients was conducted at department of ENT, Government Medical College and Hospital, Nagpur between January 2017 to February 2019. Data was collected and analysed.  </p><p class="abstract"><strong>Results:</strong> Maximum patients were of age group 40-60 years with male preponderance. Parotid being most common gland involved, 35 cases of all 43 were post-operatively confirmed to be pleomorphic adenoma.</p><p class="abstract"><strong>Conclusions:</strong> Pleomorphic adenoma is most commonly diagnosed in age group 40-60 years. Surgical excision is treatment of choice. Long term follow-up of the cases is warranted owing to risk of late recurrences.</p>

scholarly journals Taxonomic signatures of cause-specific mortality risk in human gut microbiome

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Aaro Salosensaari ◽  
Ville Laitinen ◽  
Aki S. Havulinna ◽  
Guillaume Meric ◽  
Susan Cheng ◽  
...  
Keyword(s):  
Mortality Risk ◽  
Gut Microbiome ◽  
Human Gut ◽  
Cross Sectional ◽  
Microbiome Composition ◽  
Human Gut Microbiome ◽  
Non Invasive ◽  
Sequencing Technologies

AbstractThe collection of fecal material and developments in sequencing technologies have enabled standardised and non-invasive gut microbiome profiling. Microbiome composition from several large cohorts have been cross-sectionally linked to various lifestyle factors and diseases. In spite of these advances, prospective associations between microbiome composition and health have remained uncharacterised due to the lack of sufficiently large and representative population cohorts with comprehensive follow-up data. Here, we analyse the long-term association between gut microbiome variation and mortality in a well-phenotyped and representative population cohort from Finland (n = 7211). We report robust taxonomic and functional microbiome signatures related to the Enterobacteriaceae family that are associated with mortality risk during a 15-year follow-up. Our results extend previous cross-sectional studies, and help to establish the basis for examining long-term associations between human gut microbiome composition, incident outcomes, and general health status.

The acceptance of hearing aids for children with otitis media with effusion

1999 ◽  
Vol 113 (4) ◽  
pp. 314-317 ◽  
Author(s):  
A. H. Jardine ◽  
M. V. Griffiths ◽  
E. Midgley
Keyword(s):  
Otitis Media ◽  
Hearing Aids ◽  
Otitis Media With Effusion ◽  
Binaural Hearing ◽  
Long Term Effects ◽  
Non Invasive ◽  
Parents And Children ◽  
Binaural Hearing Aids

AbstractConservative treatment for otitis media with effusion (OME) led us to consider the use of hearing aids as a way of managing the associated hearing loss. This study aimed to assess the compliance of patients and acceptance of hearing aids for the management of children with OME.Thirty-nine children who had been given binaural hearing aids to manage OME were assessed at routine follow-up after six months. A clinician who did not prescribe the aid administered a questionnaire to assess compliance, change in symptoms and acceptance of the aids.Thirty-eight parents thought the aids were easy to use and 25 (66 per cent) were completely satisfied with the management. Aided hearing improved by a mean of 17 dB (Range 10–30) over three frequencies, 0.5, 1.0, 2.0 Khz and all parents reported subjective hearing improvement in their children. The stigma of an aid was reported as minimal under the age of seven.Hearing aids provide a non-invasive way of managing the problems associated with OME which is acceptable to certain parents and children. Long-term effects of using aids need to be evaluated before they can be recommended.

Contemporary Treatment for Central Serous Chorioretinopathy

2021 ◽  
Author(s):  
Mitova D
Keyword(s):  
Subretinal Fluid ◽  
Functional Results ◽  
Clinical Results ◽  
Long Term Results ◽  
Nanosecond Laser ◽  
Success Rates ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Short And Long Term

Aim: To study the short-and long-term results of 2RT nanosecond laser treatment for CSC. To compare clinical results with those with AntiVEGF. Methods: Nanosecond laser (2RT, Ellex) was used. Patients were followed by BCVA, FAF, OCT, Angio-OCT. Results: 90% of the patient treated with 2RT had improvement of visual acuity and contrast sensitivity. 19 % [1] patients showed no improvement. 81% of the 2RT treated patients had total resorbtion of subretinal fluid against 60% treated with AntiVEGF. Functional results correlated with the atrophy of RPE in the macula. 46% (19 patients) had resolution on the first month, 23% [2]-on the third and 12% [3]-on the sixth month. The time of resolution shows no relation to the baseline pigment epithelial atrophy. Four patients presented with a recurrency of the disease in the follow-up period. 19% [1] were non responders. 60% of AntiVEGF treated eyes were responders and 40% were non responders. Those who responded to treatment needed between 3 and 10 injections. Conclusion: 2 RT is a non-invasive treatment modality with no adverse effects and high success rates.

Extramedullary Plasmacytoma of The Frontal Sinus: A Case Report

FACE ◽  
2021 ◽  
pp. 273250162110536
Author(s):  
Joshua Harrison ◽  
Samantha Marley ◽  
Shawhin Shahriari ◽  
Christian Bowers ◽  
Anil Shetty
Keyword(s):  
Frontal Sinus ◽  
Surgical Excision ◽  
Extramedullary Plasmacytoma ◽  
High Rate ◽  
Solitary Plasmacytoma ◽  
Case Presentation ◽  
Long Term Follow Up ◽  
History Of

We report a rare case of an extramedullary plasmacytoma (EMP) in the frontal sinus with an indolent clinical presentation. Although a history of trauma was absent, the initial diagnosis was a mucocele, based on the radiological findings. Upon surgical excision, the patient was found to have an EMP. EMP, a form of solitary plasmacytoma, has a significantly high rate of conversion to multiple myeloma. This mandates long-term follow-up, even after successful radiotherapy and/or resection. While radiation therapy is generally considered a first line treatment for EMP, surgical intervention may provide optimal treatment in complicated cases. This case presentation highlights the prognosis of patients diagnosed with EMP.

scholarly journals Benign tumors of the heart: Myxoma of the right atrium - a case report

2018 ◽  
Vol 75 (5) ◽  
pp. 512-515 ◽  
Author(s):  
Sasa Hinic ◽  
Jelena Saric ◽  
Predrag Milojevic ◽  
Jelena Gavrilovic ◽  
Tijana Durmic ◽  
...  
Keyword(s):  
Case Report ◽  
Body Position ◽  
Atrial Myxoma ◽  
Right Atrial ◽  
Benign Tumors ◽  
Non Invasive ◽  
Right Atrial Myxoma ◽  
The Right

Introduction. Myxoma is the most common primary benign heart tumor. The most frequent location is the left atrium, the chamber of the heart that receives oxygen- rich blood from the lungs. Myxomas usually develop in women, typically between the ages of 40 and 60. Symptoms may occur at any time, but most often they are asymptomatic or oligosymptomatic for a long period of time. Symptoms usually go along with body position, and are related to compression of the heart cavities, embolization and the appearance of general symptoms. The diagnosis of benign tumors of the heart is based on anamnesis, clinical features and findings of the tumor masses by use of non-invasive and invasive imaging methods. Extensive surgical resection of the myxoma is curative with minimal mortality. Long term clinical and echocardiographic follow-up is mandatory. Case report. We reported a case of a 62-year-old male, presented with 15 days of intermittent shortness of breath, dizziness and feeling of heart palpitations and subsequently diagnosed with right atrial myxoma based on transthoracic echocardiography . The patient was emergently operated in our hospital. Long-term followup did not reveal recurrence. Conclusion. Our case was an atypical localisation of right atrial myxoma. Whether the intracardiac mass is benign or malignant, early surgery is obligatory in order to prevent complications.

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