scholarly journals Value of Centrifugated Liquid-Based Cytology by Papanicolaou and May-Grünwald in Oral Epithelial Cells

Rare Tumors ◽  
2009 ◽  
Vol 1 (1) ◽  
pp. 9-11 ◽  
Author(s):  
Hussain Gadelkarim Ahmed ◽  
Ali Mahmmoud Edris ◽  
Eneel Ahmed Mohmed ◽  
Mohammed Omer M. Hussein

For many years, liquid-based cytology (LBC) has been developed for cervical cancer screening and not oral cancer, as it requires automated devices. The aim of this study was to compare the utility of centrifugated CLBC preparation with that of direct preparation in oral lesions, by Papanicolaou (Pap) and May Grünwald-Giemsa's (MGG) methods. A total of 100 consecutive cases of oral lesions were investigated. We compared the results obtained by the CLBC performed by cytocentrifugation with those obtained by direct smear applying Pap and MGG methods. The comparison between CLBC and direct smears was based on the thickening or adequacy of the smear, distribution of cells and staining quality. All smears in CLBC and direct preparation were found adequate. For thickness of the smear, 40% and 42% were excellent, 33% and 30% were good, and 27% and 28% were acceptable by LBC and direct preparation, respectively. For the distribution of cells and scantiness of background elements, 92 (92%) smears of the CLBC have revealed clear, well distributed smears, compared to 70 (70%) of those in direct preparation. For the staining quality with the Pap method, 39% and 69% were excellent staining quality, 25% and 20% were good, and 36% and 11% were acceptable for CLBC and direct preparation, respectively. In MGG method, 9% and 22% were excellent staining quality, 23% and 36% were good and 68% and 43% were acceptable for CLBC and direct preparation respectively. CLBC performed by cytocentrifugation is inexpensive, and reduces inadequate smears and background staining.

2012 ◽  
Vol 56 (4) ◽  
pp. 370-374 ◽  
Author(s):  
Setsu Akamatsu ◽  
Shoji Kodama ◽  
Yukari Himeji ◽  
Naomi Ikuta ◽  
Nikako Shimagaki

2021 ◽  
pp. 1-4
Author(s):  
Jyoti Patel ◽  
◽  
Sindhu Shibu Nair ◽  

Background: To better primary health care and better-trained nurses, knowing the causes of cancer provides a basis for understanding the potential for prevention or early detection of the disease. Our study aimed to assess knowledge and awareness about breast, cervical and oral cancer screening amongst oncology nurses at a tertiary cancer centre. Methodology: An anonymised questionnaire based study was conducted amongst nurses at a tertiary cancer centre. We used NCG e-leaning questionnaire to assess knowledge (which includes breast, oral and cervical knowledge and awareness related questionnaire). Results: A total of 313 participants fulfilled the inclusion criteria and were enrolled in this study. Age range of participants was from 21 to 54 years (mean = 29.8; SD = 8.14). Knowledge and awareness about breast cancer were significantly associated gender (p=0.014) and marital status (p=0.00). Although, Knowledge and awareness about cervical cancer were significantly associated with gender (p=0.002) and years of experience (p=0.03). The age (p=0.001), marital status (p=0.002) and years of experience (p=<0.001) was statistically significantly associated with knowledge and awareness about oral cancer. Conclusion: Our data suggest that levels of knowledge and understanding of cervical cancer as well as its preventable nature should be improved. Continuing nurse education may contribute to strengthen cervical cancer screening programs. Nursing staff, if properly aware of this disease, can educate the masses and hence increase health-seeking behaviour in women.


2007 ◽  
Vol 24 (4) ◽  
pp. 167 ◽  
Author(s):  
RK Sherwani ◽  
T Khan ◽  
K Akhtar ◽  
A Zeba ◽  
FA Siddiqui ◽  
...  

2019 ◽  
Vol 12 (2) ◽  
pp. 105-108
Author(s):  
Sabera Khatun ◽  
Sayada Fatema Khatun

The aim of this study was to screen the suspected cervical cancer patients (n=100) by liquid-based cytology and conventional pap’s smear followed by colposcopic biopsy from July 2016 to June 2017. In conventional pap’s test, 73 cases were true negative whereas 25 cases were false negative. However, in liquid-based cytology, 68 cases were true negative and 23 cases were false negative. Finally when colposcopic examinations were done, 61 cases were true negative and 15 cases were false negative. The sensitivity of liquid-based cytology was 11.5% for cervical cancer screening which was more than the conventional pap’s smear (3.8%). In conclusion, liquid-based cytology should be more preferable method than the than conventional pap’s smear for the diagnosis of precancerous lesion of the cervix.


2020 ◽  
pp. 601-609 ◽  
Author(s):  
Kunal Oswal ◽  
Rishav Kanodia ◽  
Akash Pradhan ◽  
Umakant Nadkar ◽  
Mahendra Avhad ◽  
...  

PURPOSE The burden of cancer is increasing globally, with poor outcomes in terms of morbidity and mortality in patients, especially in low- and middle-income countries. Lack of awareness of the risk factors, symptoms, and signs of common cancers in addition to inadequate cancer prevention programs at the community level are a major hindrance to the early detection of cancer. METHODS A cross-sectional study was conducted in the North East Region (NER) of India, with a sample population of 1,400 participants from Assam (n = 1,000), Meghalaya (n = 200), and Nagaland (n = 200). The questionnaire developed for the study consisted of sociodemographic profile, knowledge about cancer (oral, breast, and cervical), its warning signs, risk factors, and attitude toward cancer screening. Statistical analysis was performed using STATA version 13.0. RESULTS Among all the participants, 59% had heard about oral cancer, 50% about breast cancer, and 31% about cervical cancer. A limited understanding of risk factors, symptoms, and signs was reported for oral cancer (45%), breast cancer (54%), and cervical cancer (63%). A total of 34% of participants were aware of cancer screening. Among those who were aware of cancer screening, only six people had undergone any form of cancer screening, and 71% cited media as the major source of information. CONCLUSION The level of cancer awareness is low in the NER. A multipronged approach is needed with assistance from government and nongovernment organizations for training, providing adequate human resources and equipment, and developing cancer screening infrastructure. This needs to be coupled with mass media communication and interpersonal communication through frontline health workers.


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