scholarly journals Treating depression in HIV/AIDS

2007 ◽  
Vol 13 (3) ◽  
pp. 3 ◽  
Author(s):  
M Y H Moosa ◽  
F Y Jeenah
Keyword(s):  
South Africa ◽  
Social Services ◽  
Depressive Disorders ◽  
Aids Patients ◽  
Supportive Psychotherapy ◽  
Patients Experience ◽  
Reduced Adherence ◽  
Illness Progression ◽  
Hiv Negative ◽  
Hiv Aids

The prevalence of HIV/AIDS has reached alarming proportions in South Africa. Although it is strongly associated with depressive moods, there are very few published studies on its treatment in patients with HIV/AIDS. This article reviews the prevalence, treatment and potential effects of depressive disorders on immunity and adherence to antiretroviral therapy (ART).The studied prevalence of depressive disorders in HIV-positive patients varies widely, ranging from 0% to 47.8%. However, these patients have nearly twice the likelihood of having had a recent episode of major depressive disorder compared with HIV-negative individuals.<p>Currently available antidepressant medications are equally effective in treating HIV/AIDS patients and the general population. Furthermore, intervention studies have shown that psychotherapy reduces depressive symptoms and is well tolerated. Interpersonal psychotherapy is more successful than supportive psychotherapy in lessening depression, and patients experience improved functioning physically and emotionally.</p><p>Untreated depression may be associated with reduced adherence to ART, immunosuppression, and more rapid HIV illness progression. In South Africa, HIV/AIDS patients may be at greater risk for psychiatric disorder given the potentially stressful living conditions including high rates of unemployment and poverty, poor and unstable housing, inadequate social services, and high rates of crime and domestic violence. A lack of data on depression in South Africa underscores the need for further research.</p>

scholarly journals Disability Grant: a precarious lifeline for HIV/AIDS patients in South Africa

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Veloshnee Govender ◽  
Jana Fried ◽  
Stephen Birch ◽  
Natsayi Chimbindi ◽  
Susan Cleary
Keyword(s):  
South Africa ◽  
Aids Patients ◽  
Disability Grant ◽  
Hiv Aids

scholarly journals Assessment of effectiveness of traditional herbal medicine in managing HIV/AIDS patients in South Africa

2004 ◽  
Vol 81 (10) ◽  
Author(s):  
KC Tshibangu ◽  
ZB Worku ◽  
MA De Jongh ◽  
AE Van Wyk ◽  
SO Mokwena ◽  
...  
Keyword(s):  
South Africa ◽  
Herbal Medicine ◽  
Traditional Herbal Medicine ◽  
Aids Patients ◽  
Hiv Aids

scholarly journals Factors associated with chronic kidney disease in HIV+ patients in Albert Luthuli Municipality of South Africa

2020 ◽  
Author(s):  
PEPUKAI BENGURA ◽  
Principal Ndlovu ◽  
Mulalo Annah Managa
Keyword(s):  
Risk Factors ◽  
South Africa ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Antiretroviral Treatment ◽  
P Value ◽  
Aids Patients ◽  
Factors Associated ◽  
Research Findings ◽  
Hiv Aids

Abstract Background: Current research indicates that chronic kidney disease is a global problem which poses a major health threat to people of poor countries who have HIV/AIDS and are on antiretroviral treatment. In this study, the prevalence of chronic kidney disease and the factors associated with it were investigated among the HIV/AIDS patients in a rural community of South Africa. Methods: A cohort of HIV+ terminal ill patients was retrospectively followed from 2010 to 2017 until chronic kidney disease was diagnosed or until the end of the observation period at two hospitals (Carolina and Embhuleni). Patient information was obtained from the routine hospitals’ records, and the data were analysed using logistic regression and survival analysis (Kaplan-Meier hazard functions and ratios, and log-rank tests) methods. Results: Out of a random sample of 357 HIV/AIDS patients, 53 patients (14.85%) had chronic kidney disease. The factors associated with chronic kidney disease were: Gender (p-value<0.0024); Age (p-value<0.0420); Baseline creatinine (p-value<0.0116); Baseline alanine transaminase (p-value<0.0111); Treatment regimen 1 (p-value<0.0001); ART adherence (poor, fair, good) (p-value<0.0005); Hospital (p-value<0.0001); and Lost to follow-up (ye, no) (p-value<0.0069). Discussion: Whilst antiretroviral treatment is associated with some improvement in virology and immunology in HIV-infected patients, research is still needed for the assessment of the impact of ART and other risk factors on renal function in marginalised communities in Africa. Conclusion: The research findings on HIV+ patients in Albert Luthuli Municipality concurred with several previous research findings on risk factors to CKD. The expected action to alleviate the health threat due to CKD in South Africa is to educate the nation on prevention, early detection and on the management of the disease. The study established diverse baseline statistics against which future research may be based.

scholarly journals Cox regression of factors associated with the onset of chronic kidney disease in HIV/AIDS patients in Albert Luthuli Municipality of South Africa

2020 ◽  
Author(s):  
Pepukai Bengura ◽  
Principal Ndlovu ◽  
Mulalo Annah Managa
Keyword(s):  
South Africa ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Antiretroviral Treatment ◽  
Cox Regression ◽  
P Value ◽  
Aids Patients ◽  
Factors Associated ◽  
Research Findings ◽  
Hiv Aids

Abstract Background: Current research indicates that chronic kidney disease is a global problem which poses a major health threat to people of poor countries with HIV/AIDS and on antiretroviral treatment. In this study, the prevalence of chronic kidney disease and the factors associated with it were investigated among the HIV/AIDS patients in a rural community of South Africa. Methods: A cohort of HIV+ terminal ill patients was retrospectively followed from 2010 to 2017 until chronic kidney disease was diagnosed or until the end of the observation period at two hospitals (Carolina and Embhuleni). Patient information was obtained from the routine hospitals’ records, and the data were analysed using Cox regression and survival analysis (Kaplan-Meier hazard functions and ratios, and log-rank tests) methods. Results: Out of a random sample of 320 HIV/AIDS patients, 51 patients (15.9%) had chronic kidney disease. The factors associated with chronic kidney disease were: Gender (p-value=0.0356), Age (p-value=0.00077), Baseline creatinine (p-value=0.00253), Follow-up alanine transaminase (p-value=0.0152), ART treatments (p-value<0.00193) and Hospital (p-value=0.00258). Discussion: Whilst antiretroviral treatment is associated with some improvement in virology and immunology in HIV-infected patients, research is still needed for the assessment of the impact of ART and other risk factors on renal function in marginalised communities in Africa. Conclusion: The research findings on HIV+ patients in Albert Luthuli Municipality concurred with several previous research findings on risk factors to CKD. The expected action to alleviate the health threat due to CKD in South Africa is to educate the nation on prevention, early detection and on the management of the disease.

scholarly journals Collaboration Reinforces Public Private Partnerships, a Benefit to Cancer Services

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 193s-193s ◽  
Author(s):  
G.A. Walters
Keyword(s):  
South Africa ◽  
Best Practices ◽  
Private Sector ◽  
Social Services ◽  
Rural Areas ◽  
Public Private Partnerships ◽  
Basic Care ◽  
Cancer Services ◽  
Corporate Funding ◽  
Hiv Aids

Introduction: Collaboration within the Health sector in South Africa is becoming pivotal in respect of cancer, HIV-AIDS, tuberculosis and NCD's screening and treatment to communities living in South Africa. Collaboration with the private sector has been the key driver as government cannot provide funding and as part of CSI initiatives, private sector has to have a quick win. This is how NGOs receive funding from the private sector to deliver cancer services to communities within rural areas in South Africa. Our collaboration is built on Public Private Partnerships (PPP) platform. Our collaboration continues within an alliance structure that allows PinkDrive to build footprint as well as create greater platforms and networks for funding, strategic opportunities and building a greater recognized service orientated base. Objective: The primary objective of the introduction of collaboration for PinkDrive-MBTM is to create a 1-roof testing where communities/society can receive cancer and other related services from corporate funding and sponsored health/social services. The other objective is to collaborate on best practices, successful processes delivered at many points creating awareness and informing the nation who are either infected or affected by cancer. Methods: 1. We work closely with corporates who are seeking effective health campaigns for their CSI/CSR initiatives or projects. 2. Once funding is confirmed and designated areas are identified, PinkDrive/MBTM then collaborates with identified partners to take cancer and other services (health screening and testing) to the respective remote/rural area. 3. Remote areas with reduced access to specialized health and basic care services are specifically targeted especially HIV-AIDS. 4. Collaboration allows PinkDrive/MBTM and its partners to captured patient histories, identification, and treatment (pre- and postscreening) for effective screening services. Results: 1. In a collaborative structure, we have found that the patient is privy to understanding the level, importance and stage of cancer with other related illnesses. 2. Through collaborative structures, holistic healthcare services and medical treatments are monitored, measured and managed appropriately at the relevant healthcare institutions. 3. Due to the funding received by corporates for such cancer services, PinkDrive mobile trucks are on the road offering its cancer services with other partners. Conclusion: Collaborative initiatives are good success stories incorporating best practices and also benefitting the patients and medical professional. The PinkDrive-MBTM mobile truck is recognized and individuals will always elaborate on how they receive their results speedily and at their doorsteps.

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