scholarly journals Effects of iriflophenone 3-C-β-glucoside on fasting blood glucose level and glucose uptake

2015 ◽  
Vol 11 (41) ◽  
pp. 82 ◽  
Author(s):  
Chantana Aromdee ◽  
Ratree Pranakhon ◽  
Patchareewan Pannangpetch
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Uptake ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Fasting Blood Glucose Level

scholarly journals PRE-CLINICAL STUDIES ON DIABETES MELLITUS USING PARTIAL PANCREATECTOMY IN SWISS ALBINO MICE

2018 ◽  
Vol 10 (1) ◽  
pp. 71
Author(s):  
Shibu Narayan Jana ◽  
Papiya Mitra Mazumder
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Cholesterol Level ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Fasting Blood Glucose Level ◽  
Β Cells ◽  
Partial Pancreatectomy ◽  
Swiss Albino Mice ◽  
Diabetes Status

Objective: The present study was aimed at the development of partial pancreatectomy in a murine model for diabetes.Methods: Diabetes model was successfully developed by partial pancreatectomy method. In this study, cyclosporine was used for influenced the glycaemic status. Diabetes status was evaluated by fasting blood glucose level (FBG), lipid profile (by estimation of total cholesterol level and HDL-level), serum amylase and biochemical assay like glutathione estimation.Results: We report here the restoration of euglycaemic status in cyclosporine-induced diabetic in swiss albino mice after 30% pancreatectomy. In this study, Pancreatectomised (partial) group of animals showed a rapid elevation of glycaemic status, starting from 15th post observational d, but the level of significance decreased gradually from 15th (P<0.01) to 60th (P<0.05) d. This was probably due to nesidioblastotic activity which shifted the fasting blood glucose level towards normoglycaemic status with β-cells regeneration. Cyclosporine treated a group of mice showed normoglycaemic status throughout the whole experimental period, but the cholesterol level remained significant (P<0.001) till the end of the experimental d. Gradually decrements in glycaemia of the diabetic pancreatectomised animals demonstrate islets neogenesis occurring after the operative activity, leading to normoglycaemic condition, probably attributed to β-cells proliferation.Conclusion: The biochemical and histopathological evaluations suggest that there is the development of the diabetic model in the pancreatectomized group and diabetes status induced by pancreatectomy is curable to a certain extent due to the regeneration of β-cells.

Time Course Effect of Selected Carbonated Soft Drinks on Human Fasting Blood Glucose Level

2018 ◽  
Vol 3 (1) ◽  
pp. 22
Author(s):  
Osasenaga Ighodaro ◽  
Abiola Adeosun ◽  
Oyindamola FuyiWilliams ◽  
Francis Ojiko ◽  
Abeeb Akorede
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Time Course ◽  
Fasting Blood Glucose ◽  
Soft Drinks ◽  
Fasting Blood Glucose Level ◽  
Carbonated Soft Drinks

The evaluation of the agreement between fasting glycemia at the first prenatal visit and the results of the glucose tolerance test in diagnostics of gestational diabetes mellitus

2014 ◽  
Vol 60 (5) ◽  
pp. 9-14 ◽  
Author(s):  
P V Popova ◽  
A V Dronova ◽  
E R Sadikova ◽  
M P Parkkinen ◽  
M V Bol’shakova ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Glucose Tolerance Test ◽  
Fasting Blood Glucose ◽  
Tolerance Test ◽  
Fasting Blood Glucose Level ◽  
Prenatal Visit ◽  
Fasting Glycemia ◽  
The Mean

Objective. To evaluate the importance of determining fasting glycemia at the first prenatal visit for timely diagnostics of gesta- tional diabetes mellitus (GDM). Material and methods. The study included 577 pregnant women examined with the use of the oral glucose tolerance test (OGTT) during weeks 24-28 of pregnancy. The results of the test were compared with the fasting glucose level at the first prenatal visit. Results. The mean fasting blood glucose level at the first prenatal visit was 4.70±0.61 mmol/l. In 25% of the patients, fasting glycemia at this time was 5.1 mmol/l or higher. Only in 36% of the women (52 of the145 ones) with the fasting blood glucose level ≥5.1 and <7 mmol/l at the first prenatal visit, the results of OGTT were consistent with the criteria for GDM. The mean fasting blood glucose level at the first prenatal visit (up to week 16) was significantly higher than on weeks 24-28 (4.71±0.61 and 4.53±0.69 mmol/l respectively, p<0.001). The ROC analysis failed to reveal the fasting blood glucose level that could be used to predict the development of gestational diabetes with a reliable sensitivity and specific- ity. Conclusion. Further population-based investigations are needed to elucidate the relationship between fasting glycemia in the first trimester of pregnancy and its unfavourable outcome.

scholarly journals Gambaran Elektrolit dan Gula Darah Pasien Kejang Demam yang Dirawat di Bangsal Anak RSUP Dr. M. Djamil Periode Januari 2010 - Desember 2012

2013 ◽  
Vol 2 (3) ◽  
pp. 127
Author(s):  
Khairunnisa Imaduddin ◽  
Iskandar Syarif ◽  
Rahmatini Rahmatini
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Serum Sodium ◽  
Serum Potassium ◽  
Febrile Seizure ◽  
Fasting Blood Glucose ◽  
Febrile Seizures ◽  
Normal Serum ◽  
Fasting Blood Glucose Level

AbstrakKejang demam merupakan kelainan neurologik yang paling sering dijumpai pada anak. Kejang demam merupakan bangkitan kejang yang terjadi pada saat anak demam akibat proses ekstrakranial. Kejang demam terjadi pada suhu rektal >38 C. Penelitian ini bertujuan untuk mengetahui gambaran elektrolit dan gula darah pada pasien kejang demam yang dirawat di bangsal anak RSUP Dr. M. Djamil. Penelitian ini merupakan penelitian deskriptif menggunakan metode retrospektif dengan mengambil data dari bagian rekam medis RSUP Dr. M.Djamil. Sampel penelitian adalah seluruh pasien kejang demam yang dirawat di bangsal anak RSUP Dr. M. Djamil periode Januari 2010 - Desember 2012 yang memenuhi kriteria inklusi. Dari 173 kasus kejang demam, terdapat 51 kasus yang memenuhi kriteria sampel penelitian. Sebagian besar sampel merupakan kejang demam pertama (76,5%). Kejang demam kompleks didapatkan sebesar 64,7%. Kasus kejang demam terbanyak terjadi pada kelompok usia ≥6 bulan < 2 tahun yaitu sebesar 51%. Kejang demam lebih sering terjadi pada laki-laki daripada perempuan dengan perbandingan 1,4:1. Penelitian menunjukkan penurunan nilai natrium serum (n=46, 80,4%), dan kalsium serum (n=30, 63,3%), nilai kalium serum normal (n=46, 76,1%), dan peningkatan nilai gula darah sewaktu (n=45, 57,8%). Pada pasien kejang demam ditemukan penurunan nilai natrium dan kalsium serum, nilai kalium serum normal, dan peningkatan nilai gula darah sewaktu. Diharapkan penelitian yang akan datang memiliki jumlah sampel yang lebih besar untuk mengetahui gambaran elektrolit dan gula darah pada pasien kejang demam.Kata kunci: kejang demam, natrium serum, kalium serum, kalsium serum, gula darah sewaktuAbstractFebrile seizure is the most common neurological disorder found in children. Febrile seizure is seizure that occurs while the children have fever caused by extracranial process. It occurs in rectal temperature >38 C. This research aim to describe the electrolytes and blood glucose in patients with febrile seizure who were treated at the pediatric's ward of Dr. M. Djamil general hospital. From 173 cases of febrile seizures, there are 51 cases that meet the criterias of the research sample. Most of the research samples are first febrile seizure (76.5%). Complex febrile seizure occurred in 64.7%. Most cases of febrile seizures occurred in the age group ≥ 6 months - <2 years, about 51%. Febrile seizures are more common in males than females with the ratio 1.4:1. The research shows decrease serum sodium (n = 46, 80.4%), and serum calcium (n = 30, 63.3%), normal serum potassium (n = 46, 76.1%), and increase non-fasting blood glucose level (n = 45, 57.8%). The patients with febrile seizure show decrease serum sodium and calcium, normal serum potassium, and increase non-fasting blood glucose level. Expected future studies have a lot of samples in determining the electrolytes and blood glucose in patients with febrile seizure.Keywords: febrile seizures, serum sodium, serum potassium, serum calcium, non-fasting blood glucose level

scholarly journals GAMBARAN KADAR GLUKOSA DARAH PUASA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS SAM RATULANGI ANGKATAN 2011 DENGAN INDEKS MASSA TUBUH ≥ 23 kg/m2

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Gracia Rorong ◽  
Stefana Kaligis ◽  
Diana Purwanto
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Body Mass ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Fasting Blood Glucose Level ◽  
Cross Sectional ◽  
Purposive Sampling

Abstract: Glucose is a main compound that has important role in preparation and development  of energy in human body. Blood glucose level is the amount of glucose in the blood. One of the factors that affects blood glucose level is body weight. Body weight is affected by several factors, such as aged, gender, and physical activities. Overweight may cause insulin resistance, results in increasing of the blood glucose level. This study aimed to describe the fasting blood glucose level at students Faculty of Medicine year 2011 Sam Ratulangi University with Body Mass Index (BMI) ≥23 kg/m2. Research method used for this study was cross sectional descriptive survey with purposive sampling method. From 26 respondents, 12 overweight (BMI ≥23 kg/m2) respondents (46,15%) had average fasting blood glucose level 85,4 mg/dL and 14 obese (BMI ≥25 kg/m2) respondents (53,85%) had average fasting blood glucose level 86 mg/dL. Conclusion: the description of fasting blood glucose level at students Faculty of Medicine year 2011 Sam Ratulangi University with Body Mass Index (BMI) ≥23 kg/m2 is at normal level (80-100 mg/dL). Keywords: BMI ≥23 kg/m2, Fasting blood glucose, students year 2011     Abstrak: Glukosa merupakan suatu molekul utama yang berperan penting dalam penyediaan dan pembentukan energi di dalam tubuh. Kadar glukosa darah adalah jumlah kandungan glukosa dalam darah. Salah satu faktor yang mempengaruhi kadar glukosa darah adalah berat badan. Berat badan dipengaruhi oleh beberapa faktor, antara lain usia, jenis kelamin, dan aktivitas fisik. Kelebihan berat badan dapat menyebabkan resistensi insulin sehingga kadar glukosa dalam darah meningkat. Peningkatan kadar glukosa darah merupakan salah satu penanda sindroma metabolik. Penelitian ini bertujuan untuk mengetahui gambaran kadar glukosa darah puasa pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Angkatan 2011 dengan Indeks Massa Tubuh (IMT) ≥23 kg/m2. Jenis penelitian berupa penelitian survey deskriptif cross sectional dengan metode purposive sampling. Sampel penelitian sebanyak 26 orang responden. Hasil penelitian ini didapatkan 12 orang responden (46,15%) yang overweight (IMT ≥23 kg/m2) memiliki rata-rata kadar glukosa darah puasa 85,4 mg/dL dan 14 orang responden (53,85%) yang obesitas (IMT ≥25 kg/m2) memilki rata-rata kadar glukosa darah puasa 86 mg/dL. Simpulan: semua responden mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Angkatan 2011 memiliki kadar glukosa darah puasa normal (80-100 mg/dL). Kata Kunci: Glukosa darah puasa, IMT ≥23 kg/m2, mahasiswa angkatan 2011

scholarly journals Impact of Momordica Charantia (Karela) on the Fasting Blood Glucose level in the Streptozotocin-Induced Diabetic Rats

1970 ◽  
Vol 9 (1) ◽  
pp. 45-48
Author(s):  
S Mohal ◽  
DK Mondal ◽  
PK Chowdhury ◽  
A Khanom ◽  
KM Shamim
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Diabetic Rats ◽  
Momordica Charantia ◽  
Key Words Diabetes ◽  
Fasting Blood Glucose Level ◽  
The Mean

Context: Scientific studies revealed the hypoglycaemic properties of momordica charantia. The present study was carried out to find out microscopically whether Momordica charantia (karela) has got any impact lowering of FBG (Fasting Blood Glucose) level in diabetes mellitus. Study type: an experiemental study. Setting: Anatomy department of the then IPGMR (Institute of Post Graduate Medicine and Research) at present BSMMU (Bangabandhu Sheikh Mujib Medical University) and BIRDEM (Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic Disorders). Subjects: Sixty five healthy young Long Evans rats of male sex weighing 150 to 280gm aged between 10 to 12 weeks were used in this study. Methods: The rats were divided into four equal groups depending on their different sorts of dietry feeding and drug treatment. Main outcome measures: variation of differential FBG level in different groups of rat. Result: Mean 'initial' and 'final' (on day 7 and day 51 from Streptozotocin/vehicle injection) fasting blood glucose (FBG) level in the control group (Group-A) was 7.872 ± 0.60 and 8.55 ± 0.82 respectively. Therefore the mean (FBG) increased by about 13% (P = 0.022*) which is higher than that of the initial value. In untreated diabetic group the mean initial (FBG) level was 25.95 ± 8.90 and the mean final was 24.02 ± 4.08. So here, the (FBG) level decreased by about 13% (P = 0.557). On the other hand, in the insulintreated diabetic rats the mean initial (FBG) level was 24.35 ± 6.81 and the mean final was 8.38 ± 5.02, which is lower (P = 0.000*) & in the karela–treated diabetic rats, the initial (FBG) level was 23.03 ± 5.70 and the mean final was 5.65 ± 1.29 which is lower* (P = 0.000*). The value in the insulin-treated diabetic rats & in the karela-treated diabetic rats were significantly lower than that of the untreated diabetic rats (P = 0.007) & (P= 0.005) respectively. But there was no significant difference between the insulin-treated diabetic rats & the karela-treated diabetic rats (P = 0.605) in this regard. Conclusion: Karela showed a tendency of acting against hyperglycemic effects of Streptozotocin-induced diabetes mellitus. However, further investigations are recommended for establishing karela as a safe, useful effective anti- hyperglycemic agent as well as antidiabetogenic agent. Key words: Diabetes mellitus; Hyperglycemia; Momordica charantia (karela) DOI: http://dx.doi.org/ 10.3329/bja.v9i1.8148 Bangladesh Journal of Anatomy January 2011, Vol. 9 No. 1 pp 45-48  

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