An investigation of an outbreak of viral hepatitis B in Modasa town, Gujarat, India

The C Hepatitis, it is a RNA virus of the Flaviviridae family, that introduces within their spectra of infection, manifestations liverworts and extrahepatic, being these last few frequent. Crioglobulinas could be detected in a third of patient with C hepatitis, but in only 1-2% of the cases develop cutaneous manifestations, some of this manifestatios are vaculitis with acronecrosis. The infection for C hepatitis occurs in other countries with diferent prevalence, they have more prevalence than in our countrie, being different to the prevalence for other types of viral hepatitis (B hepatitis). We are introduced the case of a patient attended to in our department with infection for C hepatitis and extrahepatic manifestations(acronecrosis) associate to presence of crioglobulinas.

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The main aspects of the immunoprophylaxis of infectious diseases in the Republic of Dagestan

CHILDREN INFECTIONS ◽

10.22627/2072-8107-2019-18-3-42-45 ◽

2019 ◽

Vol 18 (3) ◽

pp. 42-45

Author(s):

N. S. Karnayeva ◽

L. U. Ulukhanova ◽

A. G. Gadzhimirzaevа ◽

S. G. Agaevа

Keyword(s):

Hepatitis B ◽

Infectious Diseases ◽

Viral Hepatitis ◽

Viral Hepatitis B ◽

The Republic ◽

Vaccine Prophylaxis ◽

Religious Reasons ◽

To Receive ◽

Positive Effect ◽

Epidemiological Situation

The analysis of the epidemiological situation of vaccine-preventable infections in the Republic of Dagestan. The introduction of mass vaccine prophylaxis had a positive effect on reducing the incidence of infections such as poliomyelitis, diphtheria, tetanus, rubella, and viral hepatitis B in the Republic of Dagestan. However, despite the ongoing routine immunization of the population for “controlled” infections, the incidence of measles and parotitis infection remains high in 2018, this is due to an increase in the number of people who refuse to receive preventive vaccinations, in most cases, for religious reasons.

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PREVALENCE AND MOLECULAR GENETIC PECULIARITIES OF PARENTERAL VIRAL HEPATITIS B AND C AMONG HIVPOSITIVE CITIZENS OF THE FAR EASTERN FEDERAL DISTRICT, INCLUDING THOSE PERSONS SENTENCED TO DEPRIVATION OF FREEDOM

ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT ◽

10.35627/2219-5238/2019-311-2-51-55 ◽

2019 ◽

pp. 51-55

Author(s):

E.A. Bazykina ◽

V.B. Turkutyukov ◽

O.E. Trotsenko ◽

V.O. Kotova ◽

L.A. Balakhonsteva ◽

...

Keyword(s):

Hepatitis B ◽

Hiv Infection ◽

Viral Hepatitis ◽

Molecular Genetic ◽

Federal District ◽

Biological Research ◽

Hiv Positive ◽

Healthy Population ◽

Genetic Characteristics ◽

Viral Hepatitis B

We conducted a comparative analysis of the parenteral viral hepatitis B and C (HBV and HCV) prevalence and their molecular genetic characteristics among prisoners of persons diagnosed with HIV infection (41 samples), HIV-positive free citizens (187 samples) and «conditionally healthy population» with the lack of information about the presence of a diagnosis of chronic viral hepatitis of any etiology and HIV infection (231 samples). Immunological and molecular biological research methods were used. Obtained data analysis showed that the prevalence of infection markers with viruses of parenteral hepatitis was significantly higher in the groups of HIV-positive individuals (imprisoned and freemen). The HBsAg-negative form of the disease was determined among the HIV-positive free population and in the «conditionally healthy population». Over the past 10 years (2009–2018), the proportion of HIV-positive prisoners in custody of people with HCV monoinfection doubled, HBV was increased in 8.7 times. Significant decrease in the combined infection of HBV and HCV of this contingent was found. Given this decrease in the penitentiary system in HIV-positive individuals, the overall burden of HBV infection (both in mono form and coinfection with HCV) significantly (5.3 times) decreased , which can be attributed to successful widespread vaccination against hepatitis B in Russia. The most common HCV genotypes among HIV-positive individuals were 1b and 3a, genotypic structure of HBV prevailed genotype D.

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