scholarly journals The main aspects of the immunoprophylaxis of infectious diseases in the Republic of Dagestan

2019 ◽  
Vol 18 (3) ◽  
pp. 42-45
Author(s):  
N. S. Karnayeva ◽  
L. U. Ulukhanova ◽  
A. G. Gadzhimirzaevа ◽  
S. G. Agaevа
Keyword(s):  
Hepatitis B ◽  
Infectious Diseases ◽  
Viral Hepatitis ◽  
Viral Hepatitis B ◽  
The Republic ◽  
Vaccine Prophylaxis ◽  
Religious Reasons ◽  
To Receive ◽  
Positive Effect ◽  
Epidemiological Situation

The analysis of the epidemiological situation of vaccine-preventable infections in the Republic of Dagestan. The introduction of mass vaccine prophylaxis had a positive effect on reducing the incidence of infections such as poliomyelitis, diphtheria, tetanus, rubella, and viral hepatitis B in the Republic of Dagestan. However, despite the ongoing routine immunization of the population for “controlled” infections, the incidence of measles and parotitis infection remains high in 2018, this is due to an increase in the number of people who refuse to receive preventive vaccinations, in most cases, for religious reasons.

Costs of viral hepatitis B in the Republic of Korea, 2002‐2015

2019 ◽  
Vol 27 (2) ◽  
pp. 156-167
Author(s):  
Dahye Baik ◽  
Byung‐Woo Kim ◽  
Jin‐Kyoung Oh ◽  
Kyung‐Ah Kim ◽  
Moran Ki
Keyword(s):  
Hepatitis B ◽  
Viral Hepatitis ◽  
Republic Of Korea ◽  
Viral Hepatitis B ◽  
The Republic

scholarly journals The search for genetic factors of predisposition to the development of liver cirrhosis in the course of viral hepatitis B in patients from the Republic of Bashkortostan

2012 ◽  
Vol 93 (2) ◽  
pp. 197-203 ◽  
Author(s):  
G T Gusmanova ◽  
D Kh Kalimullina ◽  
A B Bakirov ◽  
R I Khusainova
Keyword(s):  
Liver Cirrhosis ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Control Group ◽  
Genetic Associations ◽  
Glutathione S Transferase ◽  
Increased Risk ◽  
Viral Hepatitis B ◽  
The Republic ◽  
Severity Of The Disease

Aim. To identify the clinical and genetic associations of polymorphisms of the detoxification of xenobiotics genes during liver cirrhosis that developed as a result of viral hepatitis B. Methods. The study randomly included 38 patients with liver cirrhosis at the age of 25 to 54 years. The control group consisted of 147 healthy individuals. Conducted was an analysis of mutations in the deletion polymorphism of gene CYP1A1, leading to the replacement of the amino acid isoleucine with valine (Ile462Val) in position 462 of the cytochrome P-450 CYP1A1 and polymorphism of the gene GSTM1, which codes an enzyme antioxidant enzyme from the family of glutathione-S-transferase in patients with liver cirrhosis, which developed as a result of hepatitis B with the aim to identify possible associations with an increased risk and severity of the disease. Results. Revealed was a statistically significant increase in the proportion of patients with genotype Ile-Val/(+) compared to genotype Ile-Ile/(+), established was an association between the genotype S65C/N with polymorphism S65C of the gene HFE and liver cirrhosis of combined genesis (viral B + toxic). Conclusion. Ile462Val genotype of the CYP1A1 gene of the cytochrome P450, as well as the presence of a deletion of the glutathione-S-transferase M1 gene are risk factors for the development of liver cirrhosis secondary to hepatitis B.

scholarly journals PARENTERAL VIRAL HEPATITISES IN THE IRKUTSK REGION

2018 ◽  
Vol 3 (5) ◽  
pp. 148-153 ◽  
Author(s):  
E. D. Savilov ◽  
N. N. Chemezova ◽  
V. A. Astafev ◽  
I. V. Malov ◽  
S. I. Malov ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Viral Hepatitis ◽  
Federal District ◽  
Disease Rates ◽  
Irkutsk Region ◽  
Viral Hepatitis C ◽  
Viral Hepatitis B ◽  
Epidemiological Risk ◽  
Epidemiological Situation

From all group of infectious pathology viral hepatitises, from which the most priority are the parenteral hepatitises B and С, are essential for health of mankind, also the Irkutsk region isn’t an exception.The aim of the study:to assess an epidemiological situation in sharp and chronic forms of the viral hepatitises B and С in the territory of the Irkutsk region for the long-term period.Materials and methods. The retrospective analysis of an epidemiological situation on viral hepatitises B and C in Russia, Siberian Federal District and in the Irkutsk region for 2008–2016 is carried out.Results.The expressed decrease in incidence of acute viral hepatitis B is noted, at a chronic form of this disease rates of decrease had less expressed character that can be connected with carrying out by mass vaccinal prevention. The carried-out ranged distribution of territories for all forms of viral hepatitis B and viral hepatitis C in the Irkutsk region has allowed to reveal territories of risk.Conclusion.Parenteral viral hepatitises (sharp and chronic forms) are widespread in the territory of the Irkutsk region. From 43 administrative territories of the area, 24 belong to unsuccessful on incidences from which five are to territories of high epidemiological risk: cities of Irkutsk, Angarsk and Ust-Ilimsk and also Katangsky and Shelekhovsky districts.

Epidemiological situation of hepatitis B in the Samara region

2020 ◽  
pp. 9-16
Author(s):  
O. Churbakova ◽  
V. Akimkin ◽  
D. Pechkurov
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Acute Hepatitis ◽  
Viral Hepatitis ◽  
Chronic Hepatitis B ◽  
Causative Agent ◽  
Child Population ◽  
Acute Hepatitis B ◽  
Viral Hepatitis B ◽  
Epidemiological Situation

The article presents an analysis of the primary incidence of hepatitis B in the Samara region from 1997 to 2018. It was noted that during the 1997–2000 period there was an increase in the carrying levels of viral hepatitis B agent, the incidence of acute hepatitis B, first detected by chronic hepatitis B. Since 2000–2001, there has been a dynamic decrease in the incidence of hepatitis B. It should be noted that from the 2006 (beginning of immunoprophylaxis) to 2018. in the Samara region more intensive decrease in indicators of incidence of hepatitis B was noted. Rates of decrease in incidence of an acute hepatitis In from 2006 to 2018 in the Samara region from 7,10 ⁄ 0000 to 0,70 ⁄ 0000v 10,1 times were observed (p < 0.01). Decrease in incidence of chronic hepatitis B was noted from 2006 to 2018 by 1.4 times (p < 0.01) from 14,50 ⁄ 0000 to 10,30 ⁄ 0000. Decrease in indicators of carriage of the causative agent of viral hepatitis B from 2006 to 2018 happened more in high gear, in comparison with indicators of incidence of chronic hepatitis B to 55,60 ⁄ 0000 to 6,60 ⁄ 0000 by 8.4 times (p < 0.01). From 2008 to 2018, the vaccination coverage against hepatitis B of the child population was 99.3–99.5 %, which led to a significant decrease in the incidence of hepatitis B in the Samara region. From 2011 to 2018, no cases of acute hepatitis B of the child population of the Samara region were registered. In the last three years, no cases of chronic hepatitis B of the child population have been recorded in the Samara region.

scholarly journals Trends for incidence of chronic hepatitis B monoinfection and chronic hepatitis B+D co-infection in the Kyrgyz Republic for the period of 2010-2012

2014 ◽  
Vol 95 (6) ◽  
pp. 921-924 ◽  
Author(s):  
K A Nogoybaeva ◽  
S T Tobokalova ◽  
K T Kasymbekova ◽  
G M Zairova
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Chronic Hepatitis B ◽  
Medical Information ◽  
Chronic Viral Hepatitis ◽  
Kyrgyz Republic ◽  
Hepatitis D ◽  
Viral Hepatitis B ◽  
Epidemiological Situation

Aim. To assess the trends for the epidemiological situation of chronic hepatitis B monoinfection and chronic hepatitis B+D co-infection in the Kyrgyz Republic for the period of 2010-2012 for the development of anti-epidemic measures depending on the intensity of the process. Methods. The analysis of a database of national reporting forms on the treated cases of chronic viral hepatitis B monoinfection and chronic hepatitis B+D co-infection in primary health care units, cumulated by Republican Medical Information Center of the Ministry of Healthcare of the Kyrgyz Republic for the period of 2010-2012 was performed. Results. The incidence of chronic viral hepatitis D is identical to that of chronic viral hepatitis B (23 and 21 per 100 000 of population respectively) in the Kyrgyz Republic. Over the period of 2010-2012 the high level of total chronic hepatitis B incidence was reported in the northern part of the country (the Issyk-Kul region, 71 per 100 000, and chronic hepatitis D - in the southern part of the country (Osh, 62 per 100 000 of population). Statistically significant increase in the incidence of chronic hepatitis B in almost all regions of the country was recorded whereas only an upward trend was revealed in chronic hepatitis D incidence. Conclusion. Separate registration of patients with chronic viral hepatitis B and D in the Kyrgyz Republic starting from 2010 allowed evaluating the trends for the epidemiological situation of these diseases in different areas and developing preventive and anti-epidemic measures in regions of Kyrgyz Republic.

scholarly journals IMMUNOPROPHYLAXIS OFVIRAL HEPATITIS "B"IN THE REPUBLIC OF KAZAKHSTAN

2020 ◽  
Vol 3 (4(73)) ◽  
pp. 17-19
Author(s):  
G. K. Kazbekova ◽  
D.S. Tupenova ◽  
B. S. Malgazhdarova
Keyword(s):  
Public Health ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Health Problem ◽  
Public Health Problem ◽  
Preventive Measure ◽  
Viral Hepatitis B ◽  
Preventive Vaccination ◽  
The Republic ◽  
Effective Preventive Measure

In article presented effectiveness of conducted vaccine prevention of viral hepatitis “B” in Republic of Kazakhstan, decreasing of level of morbidity by viral hepatitis, disability because of viral hepatitis against the background of vaccination. Vaccination against hepatitis “B” is known to be an effective preventive measure. According to the program of preventive vaccination in our republic the practical use of hepatitis “B” vaccine allowed us to achieve significant in the fight against this infection.Hepatitis “B” is a priority public health problem worldwide, which is associated with a highinfection of the population with the virus, leading to dire consequencesю.

Serological and molecular-biological verification of viral hepatitis B, C, D and E in various populations of the Republic Sakha (Yakutia)

2018 ◽  
pp. 55-60
Author(s):  
S.I. Semenov ◽  
K.M. Stepanov ◽  
F.A. Platonov ◽  
S.S. Shadrina ◽  
M.M. Pisareva ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Viral Hepatitis ◽  
Viral Hepatitis B ◽  
The Republic

Monitoring of accidents with exposure to blood among medical workers of the Republic of Tatarstan

2020 ◽  
Vol 18 (6) ◽  
pp. 150-154
Author(s):  
A. I. LOKOTKOVA ◽  
◽  
I. A. BULYCHEVA ◽  
O. G. NOVIKOVA ◽  
E. Kh. MAMKEEV ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Viral Hepatitis ◽  
Medical Personnel ◽  
Healthcare Personnel ◽  
Post Vaccination ◽  
Surgical Interventions ◽  
Safety Issues ◽  
Serological Examination ◽  
Viral Hepatitis B ◽  
The Republic

Healthcare personnel are most at risk than any other profession regarding blood-borne infections due to their nature of work. The purpose is to determine the frequency and structure of accidents with blood exposure among the personnel of surgical and operating departments of two republican medical organizations in Kazan; to analyze the level of post-vaccination immunity to viral hepatitis B. Material and methods. We analyzed the data of accidents with blood exposure from registers in 2016–2018. The total amount of investigated medical personnel was 1673: doctors — 465, nurses — 1009 and nurse aids — 199. The personnel (n = 1474) was questioned about the accidents with blood exposure. Selective serological examination of 197 medical personnel for viral hepatitis B antibodies was conducted using the ELISA method (certified commercial test systems manufactured by Vektor-Best CJSC). Results. The frequency of accidents with blood exposure ranged from 7,4 to 10,5 per 1000 medical personnel. Nurses were exposed to blood-borne infections more frequently than other professions. The largest number of accidents with blood exposure is registered during surgical interventions. Most accidents with blood exposure are related to punctures (pricks) with injection and suture needles. However, according to the survey results, every third employee noted accidents with blood exposure over the past 5 years. Medical workers explain the lack of proper registration by fear of punishment and confidence in the post-vaccination immunity to the hepatitis B virus. Nevertheless, according to the serological monitoring results, 49,7% of medical personnel do not have the protective titer. Conclusion. Medical organizations should implement effective systems for monitoring and training medical personnel on epidemiological safety issues.

scholarly journals Immunoprophylaxis of infectious diseases in children of Tatarstan

2001 ◽  
Vol 82 (5) ◽  
pp. 401-403
Author(s):  
S. A. Valiullina ◽  
I. G. Chigvintseva ◽  
L. A. Doronina ◽  
L. E. Poroshenko
Keyword(s):  
Hepatitis B ◽  
Young Children ◽  
Infectious Diseases ◽  
Viral Hepatitis ◽  
Chronic Diseases ◽  
Whooping Cough ◽  
Sharp Decline ◽  
Sharp Rise ◽  
Viral Hepatitis B ◽  
Epidemic Parotitis

One-fourth of all annually reported infections are due to seven diseases that are controlled by immunoprophylaxis: diphtheria, polio, whooping cough, measles, epidemic parotitis, viral hepatitis B, and rubella. Analysis of the reasons for the sharp rise in the incidence of such diseases as diphtheria, pertussis, poliomyelitis, and measles among children in Tajikistan revealed significant omissions in vaccination work: a sharp decline in the level of coverage of young children (up to 50-60%), a large number of refusals and unjustified refusals to vaccinate, The "arbitrary" expansion of contraindications to vaccinations by specialists, the unsatisfactory level of work on immunization of children with health problems, those who are sick frequently and for long periods, those suffering from chronic diseases, and the wide use of preparations with reduced antigen content (ADS-m, DPT-m).

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