In vitro methods of surface characterization of dental erosion: A review

Author(s):  
SultanS Al-Shamrani
2003 ◽  
Vol 31 (3-4) ◽  
pp. 355-361
Author(s):  
Venetsiya R. Milkova ◽  
P. I. Ivanov ◽  
I. Todorov
Keyword(s):  

2019 ◽  
Vol 1 (3) ◽  
pp. 112-123
Author(s):  
Rohith Kumar R. ◽  
Sangeetha Ashok Kumar ◽  
K. Periyasami Bhuvana

The present study endeavors in the preparation and characterization of semi crystalline 45S5 bioglass (BG) (SiO2-CaO-P2O5) through sol gel process. Dry press mold technique was used in the preparation porous BG tablets to examine the bioactivity through invitro studies. The synthesized BG powder was subjected to structural, morphological and mechanical characterization and the bioactivity was examined in vitro by immersing the BG tablet in the Simulated Body Fluid (SBF) solution. XRD pattern and the SEM micrographs revealed the semi crystalline nature of BG with spherical morphology. The elemental analysis confirms the presence of vital constituents required for Bone regeneration (Calcium, Phosphorous, Silica, and Sodium). The surface characterization of BG tablet reveals the pores structure of average pore size of 240nm which contributed to the high surface activity resulting in formation of carbonated hydroxy apatite (HCAP) when immersed in SBF. The disintegration studies denoted the stabilization period was after 48 of immersion of BG tablets in SBF solution. The compressive strength measurement of the tablet also reveals the higher mechanical stability.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1831
Author(s):  
Jelisaveta Ignjatović ◽  
Tijana Šušteršič ◽  
Aleksandar Bodić ◽  
Sandra Cvijić ◽  
Jelena Đuriš ◽  
...  

In vitro assessment of dry powders for inhalation (DPIs) aerodynamic performance is an inevitable test in DPI development. However, contemporary trends in drug development also implicate the use of in silico methods, e.g., computational fluid dynamics (CFD) coupled with discrete phase modeling (DPM). The aim of this study was to compare the designed CFD-DPM outcomes with the results of three in vitro methods for aerodynamic assessment of solid lipid microparticle DPIs. The model was able to simulate particle-to-wall sticking and estimate fractions of particles that stick or bounce off the inhaler’s wall; however, we observed notable differences between the in silico and in vitro results. The predicted emitted fractions (EFs) were comparable to the in vitro determined EFs, whereas the predicted fine particle fractions (FPFs) were generally lower than the corresponding in vitro values. In addition, CFD-DPM predicted higher mass median aerodynamic diameter (MMAD) in comparison to the in vitro values. The outcomes of different in vitro methods also diverged, implying that these methods are not interchangeable. Overall, our results support the utility of CFD-DPM in the DPI development, but highlight the need for additional improvements in these models to capture all the key processes influencing aerodynamic performance of specific DPIs.


2007 ◽  
Vol 601 (4) ◽  
pp. 1019-1025 ◽  
Author(s):  
G.S. Senesi ◽  
E. D’Aloia ◽  
R. Gristina ◽  
P. Favia ◽  
R. d’Agostino

Author(s):  
J.L. Ong ◽  
L.C. Lucas ◽  
G.N. Raikar ◽  
J.J. Weimer ◽  
J.C. Gregory

2009 ◽  
Vol 25 (8) ◽  
pp. 969-975 ◽  
Author(s):  
Sebastian Hahnel ◽  
Martin Rosentritt ◽  
Gerhard Handel ◽  
Ralf Bürgers

Author(s):  
T. Liszczak ◽  
S. Jacobson ◽  
P. Kornblith

One property of a malignant cell is its decreased intercellular adhesiveness in vivo(l), and in vitro(2). In an attempt to visualize any morphological correlates associated with this phenomenon we utilized the replica technique to examine cell surfaces and cell to substrate attachment regions in cultured intracranial tumors, tumors from other sites and reactive cells.Cells were explanted onto glass coverslips in Leighton tubes, cultured to approximately 50%confluency, buffer rinsed, 2.5% glutaraldehyde fixed, chrome-osmium postfixed, critical point dried with Freon 13 and 113, and replicated with platinum carbon. The cells and coverslips were dissolved away by hydroflouric acid.


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