scholarly journals Indian Association for Geriatric Mental Health's multicentric study on depression in elderly: Symptom profile and influence of gender, age of onset, age at presentation, and number of episodes on symptom profile

2018 ◽  
Vol 5 (1) ◽  
pp. 35 ◽  
Author(s):  
Sandeep Grover ◽  
Ajit Avasthi ◽  
Swapnajeet Sahoo ◽  
Bhavesh Lakdawala ◽  
Naresh Nebhinani ◽  
...  
Keyword(s):  
Age Of Onset ◽  
Onset Age ◽  
Multicentric Study ◽  
Symptom Profile ◽  
Indian Association

Obsessive-Compulsive Disorder With and Without Tic Disorder: A Comparative Study From India

CNS Spectrums ◽  
2008 ◽  
Vol 13 (8) ◽  
pp. 705-711 ◽  
Author(s):  
T.S. Jaisoorya ◽  
Y.C. Janardhan Reddy ◽  
S. Srinath ◽  
K. Thennarasu
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Age Of Onset ◽  
Early Age ◽  
Obsessive Compulsive ◽  
The West ◽  
Tic Disorder ◽  
Compulsive Disorder ◽  
Symptom Profile ◽  
Spectrum Disorders ◽  
Motor Tics

ABSTRACTIntroduction: Evidence from phenomenological, family, genetic, and treatment studies from Western centers have suggested that tic-related obsessive-compulsive disorder (OCD) could be different from non-tic-related OCD. This study from India investigated the differences in OCD with and without tics, with respect to sociode-mographics, symptom profile, and comorbidity, including obsessive-compulsive spectrum disorders, to examine whether the clinical profile of tic-related OCD is similar to that reported previously.Methods: Fifty subjects with OCD and tics (chronic motor tics and Tourette syndrome) were compared with 141 OCD subjects without tics.Results: Subjects having OCD with tics tended to be males, and had an earlier onset of illness. They had more of symmetry/aggressive and religious obsessions, and cleaning, ordering/arranging, hoarding, and repeating compulsions and were associated with trichotillomania and hypochondraisis. Stepwise backward (Wald) regression analysis showed that an early age of onset, male gender, aggressive obsessions, cleaning compulsions, and trichotillomania were significantly associated with tic-related OCD.Conclusion: The findings of this study from India are broadly similar to those reported previously from the West indicating the universality of differences in tic- and non-tic-related OCD. Our findings also support the existing evidence that tics contribute to the heterogeneity of OCD.

scholarly journals Association between family history and the onset age of essential hypertension in Han population in Shanghai China

2019 ◽  
Author(s):  
li anle ◽  
Qian Peng ◽  
Yue Qin Shao ◽  
Yi Ying Zhang ◽  
Fang Xiang
Keyword(s):  
Essential Hypertension ◽  
Family History ◽  
Genetic Factors ◽  
Nuclear Family ◽  
Age Of Onset ◽  
Control Group ◽  
Case Group ◽  
Onset Age ◽  
Han Population ◽  
The Difference

Abstract Importance Genetic factors are important influencing factors of essential hypertension, and family history (FH) is an important marker of genetic factors. Objective To explore the association between family history and the onset age of essential hypertension in Han population in Shanghai China. Methods According to l:l matched pairs design，342 precursor of hypertension and 342 controls were selected and investigate their nuclear family members in the case-control study. The diagnostic information of hypertension in all relatives of these two groups was investigated. The method of genetic epidemiology research was used to explore the effect of family history. Results The average prevalence of hypertension was 23.32%. The prevalence of hypertension of first-degree relatives was 33.99%; the prevalence of second- degree relatives was 17.60%; the prevalence of third-degree relatives was 13.51%. All prevalence of hypertension of case group relatives were significantly higher than that of control group relatives. The average onset age in population with positive FH is 48.74±11.16 years old, and the average onset age in population with negative FH is 54.38±9.87 years old. The difference about two FH groups showed statistically significant (t=4.589, P<0.001). The average onset age of offspring with father, mother, grandpa, grandma, maternal grandpa or maternal grandma positive was respectively 48.42± 11.16, 49.16±11.12, 39.55±11.95, 39.88±11.90, 43.67±9.77 or 43.64±10.21 years old; and the average onset age of children with father, mother, grandpa, grandma, maternal grandpa or maternal grandma negative was respectively 51.90± 10.81, 51.17±11.04, 51.07±10.59, 51.08±10.60, 50.50±11.09 or 50.57±11.06 years old. The difference about two groups showed statistically significant. Conclusion Family history has a positive effect on the occurrence of hypertension, and lead to earlier age of onset of offspring. The effects are different among parent and grandparent in Han in Shanghai China.

Familial Alcoholism: Evidence from 237 Alcoholics

1985 ◽  
Vol 147 (1) ◽  
pp. 54-57 ◽  
Author(s):  
R. W. Latcham
Keyword(s):  
Family History ◽  
Age Of Onset ◽  
Positive Family History ◽  
Antisocial Behaviour ◽  
Onset Age ◽  
Familial Alcoholism

SummaryWhen male alcoholics with and without a positive family history were compared, differences were found in age of onset, age of presentation, severity of alcoholism, and severity of self-reported antisocial behaviour. No such differences were found for women. The implications of these findings for the concept of ‘familial alcoholism’ are discussed.

Commentary on: psychotic symptoms in frontotemporal dementia: a diagnostic dilemma?

2015 ◽  
Vol 27 (4) ◽  
pp. 529-530 ◽  
Author(s):  
John T. O’brien
Keyword(s):  
Frontotemporal Dementia ◽  
Age Of Onset ◽  
Lewy Body Dementia ◽  
Psychotic Symptoms ◽  
Diagnostic Dilemma ◽  
Fused In Sarcoma ◽  
Symptom Profile ◽  
Younger Age ◽  
Neuropathological Diagnosis ◽  
Common Causes

Frontotemporal dementia is clearly a very important condition, not only because alongside Alzheimer's disease, vascular dementia, and Lewy body dementia it is one of the four most common causes of dementia, but because its broad symptom profile and younger age of onset makes it a particularly challenging condition to diagnose and manage. In recent years, great progress has been made in understanding genetic and pathological underpinnings of frontotemporal dementias, and in characterizing specific pathological causes. In particular, three major subtypes can be delineated: those associated pathologically with tau; transactive responsive DNA binding protein (TDP-43); or fused in sarcoma (FUS). Of these, tau and TDP-43 are by far the two most common subtypes of frontotemporal dementia. In addition, there have been important genetic advances and several autosomal dominant mutations have been described, for example associated with MAPT, progranulin, and C9ORF72. However, despite these important advances regarding pathophysiological heterogeneity, relatively little is known about the frequency, nature, and correlates of psychotic symptoms in the disorder. It is therefore very timely that in this month's Paper of the Month, Waldo and colleagues (Waldo et al., 2015) describe a very detailed description of a cohort of 97 consecutive subjects seen in Lund who received a neuropathological diagnosis of frontotemporal lobar degeneration.

Age of onset of Ménière's disease in the Netherlands: data from a specialised dizziness clinic

2016 ◽  
Vol 130 (7) ◽  
pp. 624-627 ◽  
Author(s):  
B F Van Esch ◽  
P P G Van Benthem ◽  
H J Van Der Zaag-Loonen ◽  
TJ D Bruintjes
Keyword(s):  
The Netherlands ◽  
Age Of Onset ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Onset Age ◽  
Menière's Disease ◽  
Retrospective Data Analysis ◽  
Ménière's Disease

AbstractObjectives:To determine the age of onset of Ménière's disease in patients who visited a specialised dizziness clinic, and to verify whether the trend of a delayed onset age of Ménière's disease as reported for the Japanese population also occurs in the Netherlands.Method:A retrospective data analysis was performed of patients diagnosed with ‘definite’ Ménière's disease who visited our clinic between January 2000 and December 2013.Results:Mean onset age of Ménière's disease among the 296 patients was 53.0 ± 14.1 years; 209 patients (71 per cent) were diagnosed between the fifth and seventh decades of life. No trend towards a later onset of Ménière's disease was found (regression beta co-efficient for year of presentation was 0.03; 95 per cent confidence interval = −0.34–0.61; p = 0.58).Conclusion:Ménière's disease has a peak incidence between 40 and 69 years of age. No shift towards a later onset age of Ménière's disease was found.

Diagnostic delay of cluster headache: A cohort study from the Danish Cluster Headache Survey

Cephalalgia ◽  
2019 ◽  
Vol 40 (1) ◽  
pp. 49-56 ◽  
Author(s):  
Hans-Henrik Frederiksen ◽  
Nunu LT Lund ◽  
Mads CJ Barloese ◽  
Anja S Petersen ◽  
Rigmor H Jensen
Keyword(s):  
Cluster Headache ◽  
Age Of Onset ◽  
Diagnostic Delay ◽  
Onset Age ◽  
Independent Variables ◽  
Disease Awareness ◽  
Headache Onset ◽  
Diagnostic Pitfalls ◽  
Headache Patients ◽  
Demographic Features

Aim To investigate the influence of clinical and demographic features on diagnostic delay in cluster headache patients, in order to discuss diagnostic pitfalls and raise disease awareness. Methods A large, well-characterized cohort of 400 validated cluster headache patients from the Danish Cluster Headache Survey, diagnosed according to ICHD-II, were investigated. ANOVA was applied to investigate differences in diagnostic delay between groups. Selected independent variables were assessed in relation to diagnostic delay using a gamma regression model. Results Diagnostic delay was significantly reduced for each decade of cluster headache onset from 1950–2010 ( p < 0.001). Onset after 1990 was associated with shorter diagnostic delay (OR = 0.28, p < 0.001), whereas attack duration > 180 minutes (OR = 1.62, p < 0.034), migraine-like features (OR = 1.30, p < 0.043) and nocturnal attacks (OR = 1.39, p < 0.021) were associated with prolonged diagnostic delay. Further, diagnostic delay decreased with age of onset (age < 20: 13.8 years, age 20–40: 5.4 years and age > 40: 2.1 years, p < 0.001). Conclusion Diagnostic delay was reduced for every decade investigated, whereas some atypical cluster headache features were associated with prolonged diagnostic delay. Better medical education and more disease awareness are needed to prevent misdiagnosis and prolonged diagnostic delay.

scholarly journals A Comprehensive Exploration of Age of Onset for Non-Suicidal Self-Injury, Pain Experienced, and Trauma Exposure: Method, Function, and Frequency

2020 ◽  
Author(s):  
Ryan Robertson
Keyword(s):  
Age Of Onset ◽  
Trauma Exposure ◽  
Self Report ◽  
Onset Age ◽  
Self Injury ◽  
Final Sample ◽  
Two Samples ◽  
Exposure Method ◽  
Self Harm ◽  
Report Measure

The present study sought to provide a comprehensive exploration to how age of onset for non-suicidal self-injury (NSSI), pain experienced, and trauma exposure uniquely predict different, more severe characteristics of self-harm. Data was combined from two samples containing the sample measures and procedures, resulting in a final sample of 544 participants. Participants completed self-report measure assessing trauma exposure, and a measure of NSSI. Replicating and extending prior work on how an individual's age of onset impacts severity of NSSI, results indicated that those with an earlier onset age reported greater lifetime frequencies, number of methods, and NSSI functions. Greater instances of trauma exposure also predicted a greater number of methods, higher lifetime frequencies, and NSSI functions. However, pain experienced during NSSI did not have a significant impact on severity of NSSI.

scholarly journals Association between family history and essential hypertension in Han population in Shanghai China

2019 ◽  
Author(s):  
li anle ◽  
Qian Peng ◽  
Yue Qin Shao ◽  
Yi Ying Zhang ◽  
Fang Xiang
Keyword(s):  
Essential Hypertension ◽  
Family History ◽  
Nuclear Family ◽  
Age Of Onset ◽  
Study Groups ◽  
Control Group ◽  
Case Group ◽  
Onset Age ◽  
Han Population ◽  
The Difference

Abstract Backgrounds Genetic factor is one of important influencing factors of essential hypertension, and family history (FH) is an important marker of genetic factors.Objective To explore the association between family history and essential hypertension in Han population in Shanghai China.Methods The method of case-control study was used,342 cases of hypertension and 342 controls were selected and investigate their nuclear family members in the both study groups. The diagnostic information of hypertension in all relatives of these two groups was investigated. The method of genetic epidemiology research was used to explore the effect of family history.Results The average prevalence of hypertension was 23.32%. The prevalence of hypertension of first-degree relatives was 33.99%; the prevalence of second- degree relatives was 17.60%; the prevalence of third-degree relatives was 13.51%. All prevalence of hypertension of case group relatives was significantly higher than that of control group relatives. The average onset age in population with positive FH is 48.74±11.16 years old, and the average onset age in population with negative FH is 54.38±9.87 years old. The difference about two FH groups showed statistically significant (t=4.589, P<0.001). The average onset age of offspring with father, mother, grandpa, grandma, maternal grandpa or maternal grandma positive was respectively 48.42, 49.16, 39.55, 39.88, 43.67 or 43.64 years old; and the average onset age of children with father, mother, grandpa, grandma, maternal grandpa or maternal grandma negative was respectively 51.90, 51.17, 51.07, 51.08, 50.50 or 50.57 years old. The difference about two groups showed statistically significant.Conclusion Family history had a positive effect on the occurrence of hypertension, and lead to earlier age of onset of offspring. The effects were different among parent and grandparent in Han in Shanghai China.

Sign in / Sign up

Export Citation Format

Share Document