Effect of exposure to variable degrees and durations of heat on dental Barr body identification in females: An in vitro cross-sectional study

2020 ◽  
Vol 12 (2) ◽  
pp. 145 ◽  
Author(s):  
Sarah Yasser ◽  
GhadaNabil El-Sarnagawy
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Barr Body ◽  
Cross Sectional

Factors that influence in vitro fertilization treatment outcomes of Chinese men: A cross-sectional study

2016 ◽  
Vol 32 ◽  
pp. 222-226 ◽  
Author(s):  
Dan Chen ◽  
Jing Ping Zhang ◽  
Ling Jiang ◽  
Huayan Liu ◽  
Ling Shu ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Treatment Outcomes ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Chinese Men

scholarly journals Syringol metabolites as new biomarkers for smoked meat intake

2019 ◽  
Vol 110 (6) ◽  
pp. 1424-1433 ◽  
Author(s):  
Roland Wedekind ◽  
Pekka Keski-Rahkonen ◽  
Nivonirina Robinot ◽  
Vivian Viallon ◽  
Pietro Ferrari ◽  
...  
Keyword(s):  
Dietary Intervention ◽  
Meat Products ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Processed Meat ◽  
Sectional Study ◽  
Cross Sectional ◽  
Meat Intake ◽  
Hot Dog

ABSTRACT Background Processed meat intake is associated with a higher risk of colorectal and stomach cancers, coronary artery disease, and type 2 diabetes and with higher mortality, but the estimation of intake of different processed meat products in this heterogeneous food group in epidemiological studies remains challenging. Objective This work aimed at identifying novel biomarkers for processed meat intake using metabolomics. Methods An untargeted, multi-tiered metabolomics approach based on LC-MS was applied to 33 meat products digested in vitro and secondly to urine and plasma samples from a randomized crossover dietary intervention in which 12 volunteers consumed successively 3 processed meat products (bacon, salami, and hot dog) and 2 other foods used as controls, over 3 consecutive days. The putative biomarkers were then measured in urine from 474 subjects from the European Prospective Investigation into Cancer and Nutrition (EPIC) cross-sectional study for which detailed 24-h dietary recalls and FFQs were available. Results Syringol and 4 derivatives of syringol were found to be characteristic of in vitro digests of smoked meat products. The same compounds present as sulfate esters in urine increased at 2 and 12 h after consumption of smoked meat products (hot dog, bacon) in the intervention study. The same syringol sulfates were also positively associated with recent or habitual consumption of smoked meat products in urine samples from participants of the EPIC cross-sectional study. These compounds showed good discriminative ability for smoked meat intake with receiver operator characteristic areas under the curve ranging from 0.78 to 0.86 and 0.74 to 0.79 for short-term and habitual intake, respectively. Conclusions Four novel syringol sulfates were identified as potential biomarkers of smoked meat intake and may be used to improve assessment of smoked meat intake in epidemiological studies. This trial was registered at clinicaltrials.gov as NCT03354130.

scholarly journals Difference of calcium levels in Javanese, Madurese, and Chinese preeclamptic women

2018 ◽  
Vol 25 (3) ◽  
pp. 86
Author(s):  
Nuzulul Azizah Ramdan Wulandari ◽  
Ernawati Ernawati ◽  
Muhammad Ilham Aldika Akbar
Keyword(s):  
Calcium Level ◽  
Clinical Pathology ◽  
Cross Sectional Study ◽  
Total Calcium ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Clinical Chemical ◽  
Hospital Sample

Objectives: To analyse difference of calcium levels and charac-teristics between Javanese, Madurese, and Chinese pre-eclamptic women that affects preeclampsia incidence.Materials and Methods: This was a cross-sectional study with preeclamptic patients in Dr. Soetomo Hospital, Dr. M. Soewan-dhie Hospital, and Universitas Airlangga Hospital as sample. Sample was taken by measuring total calcium level in blood serum before receiving MgSO4 using in vitro clinical chemical dimension method in the Laboratory of Clinical Pathology in Dr. Soetomo Hospital. Sample was taken using consecutive sampling. Sample size 53 preeclamptic women as participants of this study, divided into three groups of Javanese, Madurese, and Chinese.Results: There were 53 preeclampsia patients, with mean ages: Javanese 31.21±5.76, Madurese 34.20±5.58, and Chinese 28.20 ±2.16. Mean BMI: Javanese 31.19±5.99, Madurese 27.66±4.74, and Chinese 26.24±2.13. We found significant difference in total calcium levels. In Madurese it was 7.7 mg/dL, Javanese was 8.3 mg/dL, and Chinese was 9.0 mg/dL (p=.000).Conclusion: The highest severity of preeclampsia was in the Madurese with low calcium levels. The lowest the calcium level, the worst the severity of the preeclampsia.

scholarly journals Consumers’ Perception of Generic Medicines and Evaluation of In Vitro Quality Control Parameters of Locally Manufactured Paracetamol Tablets in Asmara, Eritrea: A Cross-Sectional Study

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Idris Mohammed Idris ◽  
Diyae Nesredin Hassan ◽  
Hanan Abdelkadir Hassen ◽  
Rahwa Zerabruk Araya ◽  
Dawit G. Weldemariam
Keyword(s):  
Quality Control ◽  
Generic Medicine ◽  
Cross Sectional Study ◽  
In Vitro Test ◽  
Control Parameters ◽  
Sectional Study ◽  
Generic Medicines ◽  
Cross Sectional ◽  
Quality Control Parameters

Generic medicines are clinically equivalent and can be used interchangeably for their intended use. Globally, the usage of generic medicines is highly recommended because of their affordability and accessibility. However, consumers hold a negative perception and attitude of using generic medicine as they consider it poor and having inferior quality compared to branded medicines. This study was conducted to assess the consumers’ general view of generic medicines and in vitro evaluation of a locally produced generic medicine, paracetamol. An analytical and cross-sectional study was conducted in three selected hospitals, and in vitro quality control evaluation was done in National Drug Quality Control Laboratory between October 26 and November 21, 2017, in Asmara, Eritrea. A systematic random sampling design was employed, and the data was collected using a questionnaire and a check-list for recording the quality control parameters of paracetamol tablets. A total of 403 respondents were included in the study. The majority of the study participants were females (61.8%). Generally, about half (49.1%) of the respondents choose locally manufactured paracetamol over the imported ones. More than half (68.5%) of the respondents did not believe expensive medicines are of better quality. The main reason consumers prefer the local paracetamol (Azemol) tablet to the imported one was due to their good experience (62.1%). About three-fourths (78.1%) of the consumers also believed that medicines manufactured abroad confer higher quality. At the multivariate level, having educational backgrounds such as elementary ( AOR = 4.19 , 95% CI: 1.251, 14.035) and junior ( AOR = 2.4 , 95% CI: 1.146, 5.028) was associated with preferability to local paracetamol as a pain killer over the brand ones. The in vitro test of the local paracetamol met the standard specification for the identification test, weight variation test, pharmacopeial test, friability test, disintegration test, and dissolution test. In conclusion, the majority of the consumers considered local paracetamol as having an inferior quality when compared with brand paracetamol. However, the reality revealed that the local paracetamol was of the same quality as the brand ones. To facilitate widespread use of generic medicines, healthcare professionals should educate consumers on the advantages of these medicines.

scholarly journals Quality of Drug in Health Facilities: A Cross-sectional Study

2021 ◽  
Vol 18 (4) ◽  
pp. 644-648
Author(s):  
Khem Bahadur Karki ◽  
Neelam Dhakal ◽  
Baburam Humagain ◽  
Arpana Pandit ◽  
Trishna Acharya ◽  
...  
Keyword(s):  
Public Health ◽  
Storage Condition ◽  
Cross Sectional Study ◽  
Poor Quality ◽  
Health Facilities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Public Health Facilities

Background: Poor quality drugs result minor to detrimental effect on human health. The drug should be of standard quality and should be used appropriately in order to meet its therapeutic efficacy. This study aims to assess the quality of drug in Nepal. Methods: A cross sectional study was conducted in randomly selected 88 health facilities in Nepal from 10th April to 30th June 2016. Selective medicines were collected from both private licensed pharmacies and selected public health facilities. Face to face interview with health facility in-charge of selected health facilities was carried out along with the direct observation of the medicine storage room. The collected medicine samples were dispatched to two laboratories for in-vitro analysis. The labels of the collected medicine were analyzed. The obtained data were entered in Epidata version 3.1, cleaned in Microsoft excel 2007 and analyzed in SPSS version 20.Results: Out of 172 brands, nine brands of medicines were found substandard. Information regarding storage conditions, direction for use and category of the drug were lacking in the label of some brands of medicines. Some selected health facilities were found not meeting major requirements for drug storage: protection from sunlight, moisture, heat, well ventilation and proper sanitation.Conclusions: Few drugs were found to be substandard in Nepalese market from both public and private sectors. Adequate labeling and proper storage condition of medicines in health facilities were lacking.Keywords: Drug quality; private pharmacies; public health facilities; substandard drugs.

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