Bullous lichen planus of the oral cavity

The oral cavity is considered to be the window to your body because oral manifestations accompany many systemic diseases. In many instances, oral involvement precedes the appearance of other symptoms or lesions at other locations. The aim of this study is to find the correlation of these formative gingiva along with dermatological lesions. Details of patients reported with dermatological lesions to the dental hospital with oral manifestations were obtained from a detailed patient record. The data collected is tabulated graphically via SPSS for statistical analysis. 24 patients were reported with various dermatological lesions. 70% of female predilection was observed, and maximum patients carried the lesion for about 12 months. Out of the 24 patients, 70% show the presence of desquamative gingiva clinically. Histopathological diagnosis shows that 75% of the dermatological lesions present in the oral cavity is lichen planus. According to the current study population, dermatological lesions are the common cause of desquamative gingiva. The prevalence of oral lichen planus was higher and commonly seen along with desquamative gingiva.

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CONDITION OF PERIODONTAL TISSUES IN PATIENTS WITH DERMATOSES

The actual problems in dentistry ◽

10.18481/2077-7566-2018-14-4-54-57 ◽

2018 ◽

Vol 14 (4) ◽

pp. 54-57

Author(s):

Н. Чернышева ◽

N. Chernyshova ◽

Сергей Чуйкин ◽

Sergey Chuykin ◽

Гузель Акмалова ◽

...

Keyword(s):

Oral Cavity ◽

Periodontal Disease ◽

Lichen Planus ◽

Oral Lichen Planus ◽

Periodontal Diseases ◽

Complex Treatment ◽

Adequate Treatment ◽

Periodontal Tissues ◽

Periodontal Index ◽

Oral Lichen

Background. Periodontal disease is one of the most common and complex pathologies in dentistry. It is known frequently damage to the tissues of the periodontal complex with dermatoses. The most relevant among the dermatoses of the mucous membrane of the mouth and the red border of the lips is oral lichen planus. Among the six clinical forms of red flat oral lichen planus and the red border of the lips, the exudative-hyperemic and erosive-ulcerous forms occur most often. Atypical form is much less common than other forms and is often diagnosed by dentists as an inflammatory periodontal disease. At the same time, the pathogenetic mechanisms of inflammatory processes in the gums, which are different in oral lichen planus, are not taken into account, which, accordingly, complicates adequate treatment. Objectives. The aim of the study was to analyze the periodontal status in patients with exudative-hyperemic, erosive-ulcerative and atypical forms of oral lichen planus. Methods. Under our supervision there were 181 patients with oral lichen planus, in whom a simplified Green-Vermillion hygiene index was determined. To assess the state of periodontal used periodontal index according to Russell. Results. When assessing the hygienic condition of the oral cavity, high values were observed in individuals with severe forms of the disease: erosive-ulcerative, exudative-hyperemic. The highest values of the periodontal index were found in patients with atypical, erosive and ulcerative forms of oral lichen planus. Conclusions. The results of the clinical examination of patients with oral lichen planus dictate, first of all, to include in the scheme of complex treatment of it the sanitization of oral cavity and complex treatment of inflammatory periodontal diseases as well.

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Oral lichen planus with linear lichen planus: a rare association

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20191776 ◽

2019 ◽

Vol 5 (2) ◽

pp. 429

Author(s):

N. Padmapriya ◽

K. Karthikeyan

Keyword(s):

Oral Cavity ◽

Lichen Planus ◽

Rare Variant ◽

Oral Lichen Planus ◽

Skin Lesions ◽

Topical Steroids ◽

Rare Association ◽

Oral Lichen

<p class="abstract">Lichen planus (LP) is a papulosquamous disorder with both cutaneous and mucosal manifestation. Linear lichen planus is rare variant of lichen planus which occurs in the extremities. Oral lichen planus is another variant of lichen planus. Coexistence of linear lichen planus with oral lichen planus is rare and only one case has been reported before this case. A 35 year old female presented with hyperpigmented linear lesion in the leg and whitish plaques in the oral cavity. Biopsy of the skin lesions showed features of lichen planus. The patient was started on topical steroids and oral hydroxychloroquine. Patient responded to treatment.</p>

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ANALYSIS OF A CLINICAL CASE OF A PATIENT WITH RED FLAT LICHEN OF THE ORAL MUCOSA ASSOCIATED WITH THE EPSTEIN-BARR VIRUS

The actual problems in dentistry ◽

10.18481/2077-7566-20-16-1-35-41 ◽

2020 ◽

Vol 16 (1) ◽

pp. 35-41

Author(s):

Anastasiya Serazetdinova ◽

Dmitriy Trunin ◽

Valentina Kirillova ◽

Natal'ya Sultanova ◽

Mihail Postnikov

Keyword(s):

Oral Cavity ◽

Lichen Planus ◽

Oral Mucosa ◽

Epstein Barr Virus ◽

Treatment Time ◽

Treatment Plan ◽

Chronic Inflammatory Disease ◽

Barr Virus ◽

Epstein Barr

Subject. Lichen planus is a chronic inflammatory disease of the skin and mucous membranes, less commonly affecting nails and hair, the typical elements of which are papules. In the structure of diseases localized on the oral mucosa, chronic lichen planus is up to 35―40 %. A number of authors indicate the nature of the development of lichen planus in the oral cavity caused by herpes, in particular type 4 herpes virus (Epstein―Barr). The goal is to increase the efficiency of diagnosis and treatment of patients with lichen planus associated with the Epstein―Barr virus. Methodology. This article illustrates the experience of managing a patient with exudative-hyperemic form of lichen planus associated with Epstein―Barr virus and the inclusion of antiviral drugs in the treatment regimen. The paper used clinical and laboratory methods for diagnosing the conditions under study. Results. In the course of the observation, a positive clinical and laboratory dynamics of the conditions under study was revealed when applying the modernized treatment plan for lichen planus. The appointment of systemic and local antiviral therapy can reduce the treatment time for lichen planus on the mucous membrane of the oral cavity and not resort to the appointment of local hormone therapy. Conclusions. In order to increase the effectiveness of the therapy for lichen planus, it is necessary to conduct a study to identify specific DNA not only for Epstein―Barr virus, but also for all herpes viruses due to immunotropy and persistence mainly in the cells of the oral mucosa. The use of a systemic antiviral component reduces the treatment time for dental manifestations of lichen planus and eliminates the need for corticosteroid therapy, which improves the quality of life of patients.

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Lichen Planus and Lichenoid Lesions of the Oral Cavity

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348949410300613 ◽

1994 ◽

Vol 103 (6) ◽

pp. 495-497 ◽

Cited By ~ 9

Author(s):

John G. Batsakis ◽

Karen R. Cleary ◽

Kyung-Ja Cho

Keyword(s):

Oral Cavity ◽

Lichen Planus ◽

Oral Lichen Planus ◽

Clinical Manifestations ◽

Spontaneous Resolution ◽

Increased Risk ◽

History Of ◽

Cutaneous Form ◽

Oral Lichen ◽

Chronic Course

Lichen planus is a mucocutaneous disease of unknown cause that has its principal clinical manifestations in the skin and mucosa of the oral cavity. The natural history of the cutaneous form is one of spontaneous resolution over time, while oral lichen planus pursues a much more chronic course with a low order of resolution. Oral lichen planus must be distinguished from lichenoid lesions, including lichenoid dysplasia. Malignant change in oral lichen planus is rare and is prompted by carcinogenic cofactors. There is no increased risk of development of carcinoma in cutaneous lichen planus.

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CORECTION OF LOCAL IMUNITY AT PATIENTS WITH INFLAMATORY AND DESTRUCTIVE DISEASES OF ORAL CAVITY

The actual problems in dentistry ◽

10.18481/2077-7566-2013-0-4-27-30 ◽

2013 ◽

Vol 9 (4) ◽

pp. 27-30 ◽

Cited By ~ 1

Author(s):

С. Токмакова ◽

S. Tokmakova ◽

Ю. Луницына ◽

J. Lunitsyna

Keyword(s):

Oral Cavity ◽

Lichen Planus ◽

Humoral Immunity ◽

Local Immunity ◽

Cellular And Humoral Immunity

<p>The purpose of the conducted research was the assessment of influence of means for an oral cavity on a basis pantogematogena and a bergenia on factors of local immunity of an oral cavity in group of healthy faces, at patients with aftosa stomatitis and lichen planus. It is revealed that in all groups of supervision after course application of means there is an increase of values of a number of indicators of local cellular and humoral immunity.</p>

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RED FLAT LICHEN OF THE ORAL MUCOSA IN THE PRACTICE OF A DENTIST-SURGEON

Journal of Volgograd State Medical University ◽

10.19163/1994-9480-2021-1(77)-40-43 ◽

2021 ◽

Vol 77 (1) ◽

pp. 40-43

Author(s):

A.E. Kriventsev ◽

◽

V.S. Popkov ◽

Keyword(s):

Clinical Practice ◽

Oral Cavity ◽

Lymph Nodes ◽

Lichen Planus ◽

Oral Mucosa ◽

Dental Care ◽

Surgical Intervention

Currently, in the clinical practice of a dentist-surgeon, patients with various diseases, anomalies and deformities in the oral cavity are often found. The red lichen planus (CPL) is not an exception. This paper discusses the main features of the course of the disease in the oral cavity and possible approaches to therapeutic tactics in surgical intervention. Thus, patients with CPL have edema, hyperemia, multiple or single nodular rashes on the oral mucosa (SOPR), enlarged and painful lymph nodes, and discoloration of the gums. Among the main complaints are pain and bleeding in the area of the changed SOPR, which aggravates the process of surgical intervention and creates certain difficulties for the dentist-surgeon. Due to the spread of this disease among people from 30 to 60 years old, who often require dental care, clinicians need and need to have knowledge about this pathology.

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Expression of HER2/neu in premalignant lesions of oral cavity

10.1101/2020.07.24.20161489 ◽

2020 ◽

Author(s):

Vansh Verma ◽

Dr. Ashesh Kumar Jha ◽

Dr. Karsing Patiri ◽

Dr. Nikhil Arora

Keyword(s):

Oral Cancer ◽

Oral Cavity ◽

Lichen Planus ◽

Oral Lichen Planus ◽

Normal Mucosa ◽

Premalignant Lesions ◽

Severe Dysplasia ◽

Positive Contribution ◽

Cytoplasmic Staining ◽

Oral Lichen

Context: Molecular alterations in premalignant lesions of oral cavity are not well known, many reports and have found increased HER2 expression to be correlated with poor prognosis in oral cancer. However,literature on expression of HER2 in premalignant lesions is limited and data is conflicting in nature. Overexpression of HER2 in premalignant lesions may denote its positive contribution in malignant transformation of these lesions. Aims: To evaluate the expression of HER2 in premalignant lesions of oral cavity. Settings and Design: In this prospective observational study of 2 months, patients attending OPD at Department of ENT and meeting the inclusion criteria were included. Methods and Material: 23 samples of Leukoplakia and 1 sample of oral lichen planus were stained by routine H&E to confirm clinical diagnosis and assess dysplasia if any, 5 samples of normal mucosa were used as control. Immunohistochemical staining for HER2 was done. ASCO/CAP 2018 guidelines were used for reporting the results. Statistical analysis used: Percentage of lesions expressing cytoplasmic or membranous expression was calculated. Results: 1 sample of Leukoplakia with severe dysplasia expressed focal membranous staining. 20% leukoplakia lesions expressed cytoplasmic staining. Staining was not observed in oral lichen planus and leucoplakia without dysplasia. Conclusions: Membranous expression in Severe dysplasia and higher expression in oral cancer is in concordance with the multistep theory of carcinogenesis. Larger studies are needed if HER2 is to be proposed as a marker for oral premalignant lesions. Significance of cytoplasmic staining in oral premalignant lesions needs to be elucidated.

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