scholarly journals Main epidemiological characteristics and natural history of pediatric allergic rhinitis

2021 ◽  
Vol 9 (4) ◽  
pp. 203
Author(s):  
Minji Kim ◽  
Hyun Hee Kim ◽  
Hyo-Bin Kim ◽  
Yeong-Ho Rha ◽  
Yang Park ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Natural History ◽  
History Of ◽  
Epidemiological Characteristics

The natural history of allergic rhinitis in childhood

2010 ◽  
Vol 21 (6) ◽  
pp. 962-969 ◽  
Author(s):  
T. Keil ◽  
A. Bockelbrink ◽  
A. Reich ◽  
U. Hoffmann ◽  
W. Kamin ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Natural History ◽  
History Of

Natural history of allergic rhinitis A review

2001 ◽  
Vol 1 (3-4) ◽  
pp. 207-216 ◽  
Author(s):  
D Passàli ◽  
M Lauriello ◽  
C Mezzedimi ◽  
G.C Passàli ◽  
L Bellussi
Keyword(s):  
Allergic Rhinitis ◽  
Natural History ◽  
History Of

Effects of Aging on the Natural History of Seasonal Allergic Rhinitis in Middle-Aged Subjects in South Chiba, Japan

2012 ◽  
Vol 157 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Syuji Yonekura ◽  
Yoshitaka Okamoto ◽  
Shigetoshi Horiguchi ◽  
Daiju Sakurai ◽  
Hideaki Chazono ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Natural History ◽  
Seasonal Allergic Rhinitis ◽  
Middle Aged ◽  
History Of ◽  
Aged Subjects ◽  
Effects Of Aging

scholarly journals Comparing nonpharmaceutical interventions for containing emerging epidemics

2017 ◽  
Vol 114 (15) ◽  
pp. 4023-4028 ◽  
Author(s):  
Corey M. Peak ◽  
Lauren M. Childs ◽  
Yonatan H. Grad ◽  
Caroline O. Buckee
Keyword(s):  
Infectious Disease ◽  
Natural History ◽  
Influenza A ◽  
Healthcare Setting ◽  
Contact Tracing ◽  
Symptom Monitoring ◽  
History Of ◽  
Nonpharmaceutical Interventions ◽  
Epidemiological Characteristics ◽  
The Relationship

Strategies for containing an emerging infectious disease outbreak must be nonpharmaceutical when drugs or vaccines for the pathogen do not yet exist or are unavailable. The success of these nonpharmaceutical strategies will depend on not only the effectiveness of isolation measures but also the epidemiological characteristics of the infection. However, there is currently no systematic framework to assess the relationship between different containment strategies and the natural history and epidemiological dynamics of the pathogen. Here, we compare the effectiveness of quarantine and symptom monitoring, implemented via contact tracing, in controlling epidemics using an agent-based branching model. We examine the relationship between epidemic containment and the disease dynamics of symptoms and infectiousness for seven case-study diseases with diverse natural histories, including Ebola, influenza A, and severe acute respiratory syndrome (SARS). We show that the comparative effectiveness of symptom monitoring and quarantine depends critically on the natural history of the infectious disease, its inherent transmissibility, and the intervention feasibility in the particular healthcare setting. The benefit of quarantine over symptom monitoring is generally maximized for fast-course diseases, but we show the conditions under which symptom monitoring alone can control certain outbreaks. This quantitative framework can guide policymakers on how best to use nonpharmaceutical interventions and prioritize research during an outbreak of an emerging pathogen.

scholarly journals Containing Emerging Epidemics: a Quantitative Comparison of Quarantine and Symptom Monitoring

2016 ◽  
Author(s):  
Corey M Peak ◽  
Lauren M Childs ◽  
Yonatan H Grad ◽  
Caroline O Buckee
Keyword(s):  
Infectious Disease ◽  
Natural History ◽  
Influenza A ◽  
Healthcare Setting ◽  
Contact Tracing ◽  
Symptom Monitoring ◽  
History Of ◽  
Epidemiological Characteristics ◽  
The Relationship

ABSTRACTStrategies for containing an emerging infectious disease outbreak must be non-pharmaceutical when drugs or vaccines for the pathogen do not yet exist or are unavailable. The success of these non-pharmaceutical strategies will depend not only on the effectiveness of quarantine or other isolation measures but also on the epidemiological characteristics of the infection. However, there is currently no systematic framework to assess the relationship between different containment strategies and the natural history and epidemiological dynamics of the pathogen. Here, we compare the effectiveness of quarantine and symptom monitoring, implemented via contact tracing, in controlling epidemics using an agent-based branching model. We examine the relationship between epidemic containment and the disease dynamics of symptoms and infectiousness for seven case study diseases with diverse natural histories including Ebola, Influenza A, and Severe Acute Respiratory Syndrome (SARS). We show that the comparative effectiveness of symptom monitoring and quarantine depends critically on the natural history of the infectious disease, its inherent transmissibility, and the intervention feasibility in the particular healthcare setting. The benefit of quarantine over symptom monitoring is generally maximized for fast-course diseases, but we show the conditions under which symptom monitoring alone can control certain outbreaks. This quantitative framework can guide policy-makers on how best to use non-pharmaceutical interventions to contain emerging outbreaks and prioritize research during an outbreak of a novel pathogen.SIGNIFICANCEQuarantine and symptom monitoring of contacts with suspected exposure to an infectious disease are key interventions for the control of emerging epidemics; however, there does not yet exist a quantitative framework for comparing the control performance of each. Here, we use a mathematical model of seven case study diseases to show how the choice of intervention is influenced by the natural history of the infectious disease, its inherent transmissibility, and the intervention feasibility in the particular healthcare setting. We use this information to identify the most important characteristics of the disease and setting that need to be characterized for an emerging pathogen in order to make an informed decision between quarantine and symptom monitoring.

scholarly journals Analysis and natural history of pituitary incidentalomas

2016 ◽  
Vol 175 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Syed Ali Imran ◽  
Churn-Ern Yip ◽  
Netee Papneja ◽  
Khaled Aldahmani ◽  
Syed Mohammad ◽  
...  
Keyword(s):  
Natural History ◽  
Tertiary Care ◽  
Population Based ◽  
Post Surgery ◽  
Surgery Group ◽  
High Prevalence ◽  
History Of ◽  
Ischemic Attack ◽  
Epidemiological Characteristics

Objectives Pituitary incidentalomas (PI) are frequently found on brain imaging. Despite their high prevalence, little is known about their long-term natural history and there are limited guidelines on how to monitor them. Methods We conducted a retrospective study to compare epidemiological characteristics at presentation and the natural history of PI in population-based vs referral-based registries from two tertiary-care referral centers in Canada. Results A total of 328 patients with PI were included, of whom 73% had pituitary adenomas (PA) and 27% had non-pituitary sellar masses. The commonest indications for imaging were headache (28%), dizziness (12%) and stroke/transient ischemic attack (TIA) (9%). There was a slight female preponderance (52%) with a median age of 55 years at diagnosis; 71% presented as macroadenomas (>10mm). Of PA, 25% were functioning tumors and at presentation 36% of patients had evidence of secondary hormonal deficiency (SHD). Of the total cohort, 68% were treated medically or conservatively whereas 32% required surgery. Most tumors (87% in non-surgery and 68% in post-surgery group) remained stable during follow-up. Similarly, 84% of patients in the non-surgery and 73% in the surgery group did not develop additional SHD during follow-up. The diagnosis of non-functioning adenoma was a risk factor for tumor enlargement and a change in SHD status was associated with a change in tumor size. Conclusions Our data suggest that most PI seen in tertiary-care referral centers present as macroadenomas and may frequently be functional, often requiring medical or surgical intervention.

Natural history of allergic rhinitis: our experience in Italy

2003 ◽  
Vol 3 (1) ◽  
pp. 28-32 ◽  
Author(s):  
D. Passà ◽  
V. Damiani ◽  
F. M. Passà ◽  
R. Mora ◽  
G. C. Passà ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Natural History ◽  
History Of

How is the moral stance related to the intentional stance and group thinking?

2020 ◽  
Vol 43 ◽  
Author(s):  
Hannes Rakoczy
Keyword(s):  
Natural History ◽  
Social Cognitive ◽  
Intentional Stance ◽  
Cognitive Capacities ◽  
Shared Intentionality ◽  
History Of ◽  
Group Thinking ◽  
Moral Stance

Abstract The natural history of our moral stance told here in this commentary reveals the close nexus of morality and basic social-cognitive capacities. Big mysteries about morality thus transform into smaller and more manageable ones. Here, I raise questions regarding the conceptual, ontogenetic, and evolutionary relations of the moral stance to the intentional and group stances and to shared intentionality.

Sequential degranulation of eosinophils induced by antigen or autocoids in allergic humans

1986 ◽  
Vol 44 ◽  
pp. 354-355
Author(s):  
Kate W. Sjoerdsma ◽  
W. James Metzger
Keyword(s):  
Allergic Rhinitis ◽  
Bronchoalveolar Lavage ◽  
Allergic Asthma ◽  
Skin Test ◽  
Positive Skin Test ◽  
Positive Skin ◽  
Human Eosinophil ◽  
Asthmatic Patients ◽  
Allergic Asthmatic ◽  
History Of

Eosinophils are important to the pathogenesis of allergic asthma, and are increased in bronchoalveolar lavage within four hours after bronchoprovocation of allergic asthmatic patients, and remain significantly increased up to 24 hours later. While the components of human eosinophil granules have been recently isolated and purified, the mechanisms of degranulation have yet to be elucidated.We obtained blood from two volunteers who had a history of allergic rhinitis and asthma and a positive skin test (5x5mm wheal) to Alternaria and Ragweed. Eosinophils were obtained using a modification of the method described by Roberts and Gallin.

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