scholarly journals Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells reported in an asymptomatic patient: a rare case and literature review

2017 ◽  
Vol 7 (4) ◽  
pp. 51-57 ◽  
Author(s):  
Ramen Sakhi ◽  
Ameer Hamza ◽  
Muhammad Siddique Khurram ◽  
Warda Ibrar ◽  
Paul Mazzara
Keyword(s):  
Literature Review ◽  
Rare Case ◽  
Asymptomatic Patient ◽  
Giant Cells ◽  
Undifferentiated Carcinoma ◽  
Carcinoma Of The Pancreas

scholarly journals Undifferentiated carcinoma with osteoclastic giant cells of pancreas: Case report and brief literature review

2021 ◽  
Vol 6 (4) ◽  
pp. 307-310
Author(s):  
Jyoti Parag Dekate ◽  
Manjula V Kelkeri ◽  
Gowri Garudadri
Keyword(s):  
Literature Review ◽  
Giant Cells ◽  
Genetic Alterations ◽  
Undifferentiated Carcinoma ◽  
Survival Period ◽  
Prolonged Survival ◽  
Ductal Adenocarcinoma ◽  
Genetic Profile ◽  
Rare Neoplasm ◽  
Pathologic Features

Undifferentiated carcinoma with osteoclastic giant cells is a distinctive rare neoplasm involving pancreas and rarely bile ducts. This neoplasm shows characteristic histologic features with variable admixture of mononuclear histiocytic cells, non- neoplastic osteoclastic giant cells and neoplastic mononuclear cell component. Though, this tumor has been shown to share genetic alterations with pancreatic ductal adenocarcinoma, clinically, it behaves unpredictably with a substantial proportion of patient showing prolonged survival period. We present a case of this rare pancreatic tumour with brief literature review discussing the key pathologic features, immunophenotype, genetic profile and clinical behavior. Undifferentiated carcinoma with osteoclastic giant cells is a rare neoplasm in pancreas which is believed to be of epithelial origin and shares genetic aberrations with ductal adenocarcinoma. Despite this, these tumours have better prognosis with prolonged survival period.

Nasopharyngeal-Type Undifferentiated Carcinoma (Lymphoepithelioma) of Paranasal Sinuses: Rare Case and Literature Review

2006 ◽  
Vol 35 (02) ◽  
pp. 147 ◽  
Author(s):  
Jiannis K. Hajiioannou ◽  
Dionysios E. Kyrmizakis ◽  
George Datseris ◽  
Vassilios Lachanas ◽  
Alexer K. Karatzanis ◽  
...  
Keyword(s):  
Literature Review ◽  
Paranasal Sinuses ◽  
Rare Case ◽  
Undifferentiated Carcinoma

scholarly journals Undifferentiated Pancreatic Carcinoma With Osteoclast-Like Giant Cells: What Do We Know So Far?

2021 ◽  
Vol 11 ◽  
Author(s):  
Pieter Demetter ◽  
Raphaël Maréchal ◽  
Francesco Puleo ◽  
Myriam Delhaye ◽  
Sébastien Debroux ◽  
...  
Keyword(s):  
Pancreatic Carcinoma ◽  
Who Classification ◽  
Current Knowledge ◽  
Giant Cells ◽  
Undifferentiated Carcinoma ◽  
Rare Tumor ◽  
Carcinoma Of The Pancreas ◽  
Ductal Pancreatic Adenocarcinoma ◽  
Histological Appearance ◽  
Worse Prognosis

Undifferentiated carcinoma of the pancreas is an aggressive but rare tumor for which several other terms have been used to describe its histological appearance. In addition, as osteoclast-like giant cells may accompany undifferentiated carcinoma of the pancreas, the WHO Classification distinguishes undifferentiated carcinoma with osteoclast-like giant cells (UC-OGC) from plain undifferentiated carcinoma since there are a few histopathological and clinical differences. UC-OGC was initially thought to be associated with worse prognosis compared to invasive ductal pancreatic adenocarcinoma, since it is often unresectable at diagnosis and tends to recur rapidly even if completely resected. When true UC-OGGs are carefully dissected out from other anaplastic carcinomas, it becomes, however, clear that UC-OGCs do have more indolent behavior, especially the pure UC-OGCs. This mini-review summarizes the current knowledge on UC-OGC.

scholarly journals Undifferentiated Carcinoma of the Pancreas with Osteoclast-Like Giant Cells: Initially Diagnosed as Solid Pseudopapillary Tumor

2016 ◽  
Vol 21 (3) ◽  
pp. 144-149
Author(s):  
Woohyeon Kim ◽  
In Seok Lee ◽  
Eunyoung Kim ◽  
Chul-Hyun Lim ◽  
Jin Su Kim ◽  
...  
Keyword(s):  
Giant Cells ◽  
Undifferentiated Carcinoma ◽  
Solid Pseudopapillary Tumor ◽  
Carcinoma Of The Pancreas

scholarly journals Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Vani Krishnamurthy ◽  
Sheela Devi C. Shivalingiah ◽  
Sunila Ravishankar ◽  
Gubbanna V. Manjunath
Keyword(s):  
Giant Cell ◽  
Rare Case ◽  
Giant Cells ◽  
Undifferentiated Carcinoma ◽  
Rare Tumor ◽  
Cell Type ◽  
Epithelial Component ◽  
Giant Cell Type

Carcinosarcoma is a rare tumor composed of variable proportions of carcinomatous and sarcomatous elements and comprises less than one percent of all gallbladder malignancies. In most reported cases of carcinosarcoma of gallbladder, the epithelial component is adenocarcinoma. The mesenchymal component varies from homogenous sarcoma to more heterotopic elements like malignant bone, cartilage, and other mesenchymal tissues. We report a rare case of carcinosarcoma of the gallbladder in an 83-year-old male, with the carcinomatous component represented by undifferentiated carcinoma (spindle and giant cell type with osteoclastic giant cells) and the mesenchymal component seen as foci of chondrosarcoma.

scholarly journals Undifferentiated Carcinoma with Osteoclast-Like Giant Cells of the Pancreas Mimicking a Predominantly Calcified Mass: Case Report and Literature Review

2019 ◽  
Vol 80 (3) ◽  
pp. 585
Author(s):  
Tae Seop Choi ◽  
Jongmee Lee ◽  
Baek Hui Kim ◽  
Jae Woong Choi ◽  
Kyeong Ah Kim ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Giant Cells ◽  
Undifferentiated Carcinoma ◽  
Mass Case
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