Marco Mineoff, "The Structural Pattern of Shakespeare's Tragedies"

2014 ◽  
pp. 211-218
Keyword(s):  
1982 ◽  
Vol 55 (3) ◽  
pp. 720-722
Author(s):  
Anat Scher

The effect of the position of lines on length estimation was investigated. 40 5-yr.-olds were asked to compare the two arms of an L-shaped figure presented inside circular frames of different diameters. For each figure one of the arms was on the axis, that is, the diameter, and the other arm was perpendicular to that axis. In making perceptual judgments about the relative length of two lines the children tended to describe the on-axis line as longer than the off-axis line. This illusion which, presumably, reflects a perceptual force induced by the characteristics of the structural pattern, supports the context model of visual anomalies.


2019 ◽  
Vol 16 (10) ◽  
pp. 1157-1166
Author(s):  
Rodrigo César da Silva ◽  
Fabiano Veiga ◽  
Fabiana Cardoso Vilela ◽  
André Victor Pereira ◽  
Thayssa Tavares da Silva Cunha ◽  
...  

Background: : A new series of O-benzyloximes derived from eugenol was synthesized and was evaluated for its antinociceptive and anti-inflammatory properties. Methods: : The target compounds were obtained in good global 25-28% yields over 6 steps, which led us to identify compounds (Z)-5,6-dimethoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-one-O-(4- (methylthio)benzyloxime (8b), (Z)-5,6-dimethoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-one-O-4- bromobenzyloxime (8d) and (Z)-5,6-dimethoxy-2,2-dimethyl-2,3-dihydro-1H-inden-1-one-O-4- (methylsulfonyl)benzyloxime (8f) as promising bioactive prototypes. Results:: These compounds have significant analgesic and anti-inflammatory effects, as evidenced by formalin-induced mice paw edema and carrageenan-induced mice paw edema tests. In the formalin test, compounds 8b and 8f evidenced both anti-inflammatory and direct analgesic activities and in the carrageenan-induced paw edema, with compounds 8c, 8d, and 8f showing the best inhibitory effects, exceeding the standard drugs indomethacin and celecoxib. Conclusion: : Molecular docking studies have provided additional evidence that the pharmacological profile of these compounds may be related to inhibition of COX enzymes, with slight preference for COX-1. These results led us to identify the new O-benzyloxime ethers 8b, 8d and 8f as orally bioactive prototypes, with a novel structural pattern capable of being explored in further studies aiming at their optimization and development as drug candidates.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Michela Quadrini

Abstract RNA molecules play crucial roles in various biological processes. Their three-dimensional configurations determine the functions and, in turn, influences the interaction with other molecules. RNAs and their interaction structures, the so-called RNA–RNA interactions, can be abstracted in terms of secondary structures, i.e., a list of the nucleotide bases paired by hydrogen bonding within its nucleotide sequence. Each secondary structure, in turn, can be abstracted into cores and shadows. Both are determined by collapsing nucleotides and arcs properly. We formalize all of these abstractions as arc diagrams, whose arcs determine loops. A secondary structure, represented by an arc diagram, is pseudoknot-free if its arc diagram does not present any crossing among arcs otherwise, it is said pseudoknotted. In this study, we face the problem of identifying a given structural pattern into secondary structures or the associated cores or shadow of both RNAs and RNA–RNA interactions, characterized by arbitrary pseudoknots. These abstractions are mapped into a matrix, whose elements represent the relations among loops. Therefore, we face the problem of taking advantage of matrices and submatrices. The algorithms, implemented in Python, work in polynomial time. We test our approach on a set of 16S ribosomal RNAs with inhibitors of Thermus thermophilus, and we quantify the structural effect of the inhibitors.


2018 ◽  
Vol 25 (87) ◽  
pp. 610-631 ◽  
Author(s):  
Ana Raquel Coelho Rocha ◽  
Leticia Moreira Casotti

Abstract This study sheds light on the perspective of Black female consumers in regard to certain effects of marketing initiatives adopting the literature on demarketing as a framework. The context examined is their experience with the market of hair beauty and care. Media actions are analyzed along with narrative interviews in order to understand the phenomenon. The findings reveal a dominant structural pattern which perpetuates the marginalized status of Black women’s natural traits. Emerging market initiatives point to movements concerning the visibility of these female consumers, who despite being eager to consume, have their demand discouraged. This suggests that they perceive selective and veiled demarketing as one of the results of marketing actions. The analysis invites for theoretical reflections on demarketing and veiled racism in Brazil.


1999 ◽  
Vol 88 (4) ◽  
pp. 291-304 ◽  
Author(s):  
G Etiope ◽  
P Beneduce ◽  
M Calcara ◽  
P Favali ◽  
F Frugoni ◽  
...  

2020 ◽  
Vol 40 (4) ◽  
pp. 876-900
Author(s):  
Rico Walter ◽  
Alexander Lawrinenko

Abstract The paper on hand approaches the classical makespan minimization problem on identical parallel machines from a rather theoretical point of view. Using an approach similar to the idea behind inverse optimization, we identify a general structural pattern of optimal multiprocessor schedules. We also show how to derive new dominance rules from the characteristics of optimal solutions. Results of our computational study attest to the efficacy of the new rules. They are particularly useful in limiting the search space when each machine processes only a few jobs on average.


1981 ◽  
Vol 28 (1) ◽  
pp. 23-39
Author(s):  
B. R. Rees

These are the opening words of Aristotle's Poetics, generally recognized as the most influential work in the history of Western European drama and poetic theory since the Renaissance. The initial statement of the scope of the inquiry is a formidable one; but a reader coming to it for the first time might well be forgiven for concluding that it promises far more than it achieves. Is it possible, he might ask, that all this is contained in a slim volume occupying no more than 47 pages in the Oxford Classical Text and 45 in the Penguin translation? Reading further, he might become even more disillusioned: what he discovers is that, after a very brief and perfunctory introduction on poetry as a form of mimesis or artistic representation, Aristotle limits himself to a discussion of tragedy, a cursory treatment of epic, and a few passing references to comedy, and that, even in the case of tragedy, by far the major part of the argument is devoted to an examination of plot. Can this really be the work which excited scholars in the Renaissance, inspired Milton to write Samson Agonistes, an Aristotelian drama if there ever was one, provided the structural pattern and dramatic conventions for the plays of Racine and Corneille, gave Fielding the principles on which he based his Tom Jones, influenced Goethe and Lessing and, through Lessing, Coleridge, and has won the attention and admiration of critics writing in English from James Harris at the end of the eighteenth century to Richard MacKeon in the second half of the twentieth? And, if so, why?


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