scholarly journals To assess the adherence to antiretroviral therapy among HIV positive patients attending ART centres in Haryana and its effect on their quality of life

2021 ◽  
Vol 33 (2) ◽  
pp. 314-318
Author(s):  
Arundeep Singh ◽  
Anshu Mittal ◽  
Vishavdeep Kaur
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Art Therapy ◽  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Cross Sectional Study ◽  
Adherence Rate ◽  
Hiv Positive ◽  
Cross Sectional

Background: Acquired immune deficiency syndrome (AIDS) is now considered as a manageable chronic illness with the availability of ART. A high level of adherence (>95%) is required for antiretroviral therapy to be effective. It is a syndrome that builds a vacuum in a person affecting his/her quality of life (QOL) as a whole. Aim& Objective: The aim of our study was to determine adherence and its effect on their quality of life among HIV/AIDS patients attending FIART (Facility Integrated Anti-retroviral therapy) clinic. Materials and Methods: Using a cross-sectional study design,  257 HIV positive patients receiving antiretroviral therapy at Facility integrated anti-retroviral therapy centre Ambala Haryana. QOL of patients taking ART was assessed using WHO-QOL-BREF questionnaire.  Results: Of 257 participants, 88.3% were found to be adherent, adherent to ART therapy and ambulatory had better QOL (p < 0.05) than their counterparts from other socio-clinical strata. Mean scores of physical (70.89±7.384), psychological (47.37±9.174), social (51.97±11.119) & environmental domains (52.33±9.081), were having highest in patients those who were adherent (adherence rate >95%) to ART therapy. Conclusion: Adherence to antiretroviral therapy in Haryana India is suboptimal. Intensive adherence counselling should be provided to all patients before initiation of antiretroviral therapy and on every visit to FIART centre.

scholarly journals A cross-sectional study on caregivers’ perspective of the quality of life and adherence of paediatric HIV patients to Highly Active Antiretroviral Therapy 

2020 ◽  
Author(s):  
Michael Lahai ◽  
Peter Bai. James ◽  
Noel N. Wannang ◽  
Haja R. Wurie ◽  
Sorie Conteh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Nuclear Family ◽  
Strong Association ◽  
Hiv Positive ◽  
Cross Sectional ◽  
Highly Active ◽  
Health Domains

Abstract Background: Poor compliance to highly active antiretroviral therapy (HAART) can result in the poor quality of life in children living with HIV/AIDS because of low plasma drug concentration and the possibility of drug resistance. This study evaluates the response of caregivers for determination of adherence and the four quality of life domains in children (aged 14 years and under) on HAART.Methods: We conducted a cross-sectional study of 188 children, each accompanied by their caregivers at Ola During Children's Hospital and Makeni Government Hospital between September and November 2016. Adherence to HAART and Quality of life was assessed using the WHO Quality of life summary questionnaire (WHOQOL-BREF). We obtained ethical approval from the Sierra Leone Ethics and Scientific Review Committee. Results: The study revealed 5.9% adherence amongst paediatric patients, and a strong association of adherent patients(p=0.019*) to the physical health domain (mean=64.61 SD=8.1).Caregiver HIV status showed a strong association with the physical (mean=58.3, SD=11.7 and p=0.024*), and psychological health domains (mean=68.2, SD=14.7 and p=0.001). Caregiver type (mother/father/sibling) accompanying child to hospital also showed strong associated with the physical (mean=58.0, SD=10.6, p <0.001), psychological (mean 68.2 SD=14.81 p <0.001) and environmental health domains (mean=59.7, SD=13.47, p <0.001). Further regression analysis showed a strong association with physical health domain for HIV positive caregivers (p=0.014) and adherent paediatric patients (p=0.005). Nuclear family also showed a strong association with psychological (p<0.001) and environmental (p=0.001) health domains. Conclusion: This study showed a strong association between the quality of life domains and the involvement of nuclear family caregiver, HIV-positive caregiver and adherence to HAART. Our study suggests that the involvement of any member of the nuclear family, HIV positive parents and patient adherence to therapy can improve the quality of life of paediatric HIV/AIDS patients on highly active antiretroviral therapy in the two hospitals.

scholarly journals Evaluation of quality of life and associated factors among HIV patients on antiretroviral therapy in North West region of Cameroon

2021 ◽  
Vol 21 (1) ◽  
pp. 8-17
Author(s):  
Anissette N Busi ◽  
Marius Nsoh ◽  
Moses O Otieno ◽  
Sylvester A Ndeso ◽  
Gregory E Halle-Ekane
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Physical Factors ◽  
People Living With Hiv ◽  
Hiv Patients ◽  
Cross Sectional ◽  
North West

Background: There is evidence that Quality of Life (QoL) of People Living with HIV/AIDS (PLHIV) has a significant role in ART retention, treatment adherence, and survival. As a result, QoL is becoming increasingly important for policy- makers, program implementers, and researchers. However, factors associated with QoL, in a culturally diverse country like Cameroon are unknown. Objective: We aimed to assess the QoL of PLHIV on ART and assess the extent to which physical, psychosocial, environ- mental, and spiritual factors drive QoL. Method: A cross-sectional study was conducted among 394 PLHIV aged >21 in North-West Cameroon from April to July 2019. Data were collected using WHO-QOL BREF questionnaire. Descriptive statistics, bivariate, and multivariate linear regression analyses were performed. Results: Majority (34.5%) of participants were in the age range of 41-50, with 73% females. The average QoL of the re- spondents was “good” with mean score of 3.57 on 5 and 71.4% agreed to have satisfactory QoL. Bivariate regression anal- yses revealed that all six proposed predictors were significantly associated with QoL. Psychological factors made the greatest impact (β = 0.213; p<0.003), followed by physical factors (β = 0.19; p<0.001). Conclusion: PLHIV fairly agreed to have good QoL. The QoL was driven by mainly psychological and physical factors and not level of independence. However, the mean score perceptions for the investigated domains were low. Mental health ser- vices should consider these predictors when designing strategies to improve the QoL of PLHIV. While this study provides useful insights, other possible drivers of QoL among PLHIV should be investigated. Keywords: Quality of life and associated factors; HIV patients; antiretroviral therapy; Cameroon.

scholarly journals Depression with pain co morbidity effect on quality of life among HIV positive patients in Uganda: a cross sectional study

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Emmanuel K. Mwesiga ◽  
Levi Mugenyi ◽  
Noeline Nakasujja ◽  
Shirley Moore ◽  
Mark Kaddumukasa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
Hiv Positive ◽  
Sectional Study ◽  
Cross Sectional ◽  
Co Morbidity

Human immunodeficiency virus/acquired immunodeficiency syndrome–related cancer in the pre- and post-highly active antiretroviral therapy era in a national cancer center of a resource-limited country: 1988 to 2007

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e20550-e20550
Author(s):  
L. E. Cuéllar Ponce de León ◽  
L. M. Miranda Rosales ◽  
C. Biminchumo Zagástegui ◽  
R. Rosales Cusichaqui ◽  
C. Flores ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Invasive Cervical Cancer ◽  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Cross Sectional Study ◽  
Cancer Center ◽  
Cross Sectional ◽  
Highly Active ◽  
Resource Limited

e20550 Background: The introduction of the highly active antiretroviral therapy (HAART) has changed the clinical course of acquired immune deficiency syndrome (AIDS) related to cancer. The goals were to describe the the characteristics of AIDS related to cancer before and after HAART in patients in a Hospital of a resource-limited country. Methods: This was an observational, retrospective and cross sectional study. Comparisons analyzed with X2 test. Survival estimated with Kaplan-Meier estimates. Results: The population included 426 (52.2%) patients. The mean age was 39 y.o. The main group was heterosexual 51.1%. The number of invasive cervical cancer (CC) and AIDS-related lymphomas (ARLs) increased in the Post HAART era; the number on non-HIV/AIDS related to cancer has decreased. During the first period none of patients had antiretroviral therapy, living patients was 62% in the Post HAART era (p< 0.01). Conclusions: The introduction of HAART has reduced the number of non-VIH/AIDS related cancer, but have increased the CC and LNH and improved the survival of patients. [Table: see text] No significant financial relationships to disclose.

Successive switching of antiretroviral therapy is associated with high psychological and physical burden

2007 ◽  
Vol 18 (10) ◽  
pp. 700-704 ◽  
Author(s):  
Lorraine Sherr ◽  
Fiona Lampe ◽  
Sally Norwood ◽  
Heather Leake-Date ◽  
Martin Fisher ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Treatment Options ◽  
Symptom Burden ◽  
Hiv Treatment ◽  
Self Report ◽  
Hiv Positive ◽  
Cross Sectional ◽  
The Impact

HIV treatment and management is constantly evolving. This is as a result of more treatment options coming on stream, tolerance changes and progress in treatment management. HIV infection today, in resource-rich countries and in the presence of combination therapies, is experienced as lifelong treatment punctuated by adjustments to antiretroviral therapy (ART) regimens. People who are diagnosed as HIV positive face a number of challenges and changes around the decision to commence treatment, responses to treatment and changes in treatment regimens. This study was set up to examine the experience of switching treatments and the impact of such switches on psychological parameters. The method used was a cross-sectional questionnaire study. A group of 779 HIV-positive clinic attendees at four clinics in London and South East England participated in the study (86% response rate). They provided detail of their treatment switching experiences as well as demographic details, risk and optimism evaluations, quality of life, symptom burden, adherence and disclosure information. The sample ( n=779) comprised 183 (24%) females, 76 (10%) heterosexual males and 497 gay males (66%). Self-reported ethnicity was 67% white, 25% black, 3% Asian and 5% mixed/other ethnicity. One hundred and fifty-five (21%) were ART-naïve and 624 (79%) were ART experienced; 161 (22%) were receiving their first regimen, 135 (18%) had experienced one regimen switch, 196 (26%) had multiple switches and 99 (13.3%) had stopped treatment. Treatment naïve, non-switchers and single switchers generally reported lower symptom burden and higher quality of life. Multiple switchers reported higher physical symptom burden and higher global symptom distress scores. Those who had stopped treatment had significantly lower quality-of-life scores than all other groups. Suicidal ideation was high across the groups and nearly a fifth of all respondents had not disclosed their HIV status to anyone. Reported adherence was suboptimal – 79% of subjects were at least 95% adherent on self-report measures of doses taken over the preceding week. In conclusion, nearly half this clinic sample will have switched treatments. A holistic approach is needed to understand the psychological effects of such switches if lifelong treatment is to be maintained and those on antiretroviral treatment are to attain good quality of life and minimize symptom burden.

scholarly journals Awareness about Tuberculosis in people living with HIV/AIDS: A cross Sectional Institutional Study.

2015 ◽  
Vol 13 (1) ◽  
pp. 9-13
Author(s):  
Bikal Shrestha ◽  
Kapil Pandya ◽  
Barun Patel ◽  
Rubina Shrestha Shrestha ◽  
Raj Kumar
Keyword(s):  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Cross Sectional Study ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Cross Sectional ◽  
Infected People ◽  
Attitudes And Practices ◽  
Route Of Transmission ◽  
Common Opportunistic Infection

Introduction: Worldwide, Tuberculosis (TB) is the most common opportunistic infection affecting HIV seropositive individuals and it remains the most common cause of death in patients with Acquired Immune Deficiency Syndrome. It is estimated that 50 to 60% of HIV infected people will develop TB in their lifetime. Keeping this in background this study was planned to assess the knowledge, attitudes and practices on TB in HIV positive patients. Methods: A cross sectional study was carried out in HIV positive individuals attending an ART centre. 100 attendees were selected by systematic random sampling method and interviewed with a pretested, structured questionnaire. Results: In the study 37.2% of respondents were not aware about air/droplet as a route of transmission of TB. Only 10% knew that infective organisms as a common opportunist infection in people with HIV & AIDS. 78.2% of the study population felt that the community will treat them differently if they suffer from TB and total of 57.7% confirmed an attitude of hiding the disease in them. Conclusion: The overall knowledge about TB in HIV positive individuals is low. Efforts must be made to counsel the patients about TB right in the first counselling session that the patient attends in ART centres so as to prevent spread of TB in the community.doi: http://dx.doi.org/10.3126/mjsbh.v13i1.12993 

scholarly journals Oral health related quality of life among HIV positive patients attending two HIV outpatient clinics in Nigeria - a cross sectional study

2021 ◽  
Vol 21 (2) ◽  
pp. 566-575
Author(s):  
Kehinde Adesola Umeizudike ◽  
Babatope Bamidele Osagbemiro ◽  
Opeyemi Oluwayemisi Daramola ◽  
Titilope Adenike Adeyemo
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Dental Treatment ◽  
Cross Sectional Study ◽  
Hiv Positive ◽  
Cross Sectional ◽  
Perceived Need ◽  
Related Quality ◽  
Health Related

Background: The human immunodeficiency virus infection remains a devastating disease of public health importance. Objectives: To assess the association between oral health and quality of life and the factors affecting the oral health related quality of life among HIV positive patients in Nigeria. Methods: This was a cross sectional study of HIV positive patients attending two HIV outpatient clinics in Nigeria. Impact of oral health on quality of life was assessed using the OHIP-14. Oral health status was assessed by the DMFT and Simpli- fied OHI indices. Level of significance was set at p< 0.05. Results: Three hundred and fifty-two patients were seen, 64.2% being females. Prevalence of impact was 8.5%; and the mean OHIP scores was 8.05±9.54. Highest impact was “painful aching” 67(19.1%) with the domain of physical pain scoring the highest mean impact of 2.32. Most patients (88.6%) were on HAART. Following logistic regression, after controlling for potential confounders, independent factors associated with poor OHRQoL were perceived need for dental treatment, HAART use, and higher DMFT (p<0.05). Conclusion: The domain of physical pain had the highest impact, while perceived need for dental treatment, HAART use and higher caries index were contributory to poor OHRQoL. Keywords: HIV infection; Oral health; OHRQoL.

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