scholarly journals The Use of Serial Non EPI DWI MRI Scans to Determine the Growth of Cholesteatoma

2021 ◽  
Vol 28 (3) ◽  
pp. 215-220
Author(s):  
Wendy K Smith ◽  
Leena Naidu ◽  
Hemanth Kowdley Subrahmanyam
Keyword(s):  
Longitudinal Study ◽  
Middle Ear ◽  
Surgical Intervention ◽  
Rate Of Growth ◽  
Median Period ◽  
Mri Scans ◽  
Serial Mri

Introduction  It is an established practice to use non-EPI DWI MRI scans to detect the presence of cholesteatoma post operatively.  In the present era of Covid-19 where routine surgery to remove cholesteatoma has been suspended resulting in potentially unprecedented demands on the service, a review of serial MRI scans performed over a 7 year period was undertaken to determine the rate of growth of cholesteatoma. Materials and Methods  A retrospective longitudinal study identified 24 middle ear cholesteatomas in 17 patients with serial non-EPI DWI MRI scans (having excluded those having surgical intervention between scans) for a median period of 33 months (range of 6-91 months).  Cholesteatomas were measured by the first author and by the consultant radiologist. Results   Of 24 cholesteatomas, 1 resolved completely, 5 reduced, 6 stayed the same size, 4 grew slowly and 8 grew significantly. Conclusion   Non-EPI DWI MRI scans to determine cholesteatoma growth in asymptomatic ears is useful in triaging patients in the Covid-19 era.

scholarly journals Acute Disseminated Encephalomyelitis Associated with Pasteurella multocida Meningitis

2003 ◽  
Vol 30 (2) ◽  
pp. 155-158 ◽  
Author(s):  
Normand L. Proulx ◽  
Mark S. Freedman ◽  
James W. Chan ◽  
Baldwin Toye ◽  
Cathy C. Code
Keyword(s):  
Case Report ◽  
Antibiotic Treatment ◽  
Pasteurella Multocida ◽  
Clinical Course ◽  
Acute Disseminated Encephalomyelitis ◽  
Persistent Fever ◽  
Mri Scans ◽  
One Year ◽  
Culture Positive ◽  
Serial Mri

ABSTRACT:Objective:To describe a case of Pasteurella multocida meningitis associated with acute disseminated encephalomyelitis (ADEM).Case report:A 33-year-old woman employed in a dog pound presented herself to hospital with fever and meningismus and was found to have culture positive Pasteurella multocida meningitis. Despite appropriate antibiotic treatment her clinical course was characterized by a persistent fever and worsening encephalopathy, which prompted further neurological investigation. Spinal fluid exam and serial MRI scans as well as her one-year clinical course were found to be compatible with ADEM.Conclusion:Persistent fever and worsening encephalopathy in meningitis may indicate a para-infectious immune process such as ADEM, and may serve as indications for further neurological investigation.

Measurement of hippocampal volume changes in serial MRI scans

1999 ◽  
Author(s):  
Julia A. Schnabel ◽  
Louis Lemieux ◽  
U. C. Wieshmann ◽  
Simon R. Arridge
Keyword(s):  
Hippocampal Volume ◽  
Volume Changes ◽  
Mri Scans ◽  
Serial Mri

A Longitudinal Study of Cellular Changes in Experimental Otitis Media

1979 ◽  
Vol 87 (5) ◽  
pp. 685-700 ◽  
Author(s):  
Marcos V. Goycoolea ◽  
Michael M. Paparella ◽  
Anna Mary Carpenter ◽  
S. K. Juhn
Keyword(s):  
Longitudinal Study ◽  
Otitis Media ◽  
Experimental Animal ◽  
Middle Ear ◽  
Defense System ◽  
Tube Obstruction ◽  
Defense Systems ◽  
Cellular Changes ◽  
Staining Techniques ◽  
The Continuum

A longitudinal sequential study of otitis media in an experimental animal (cat) using eustachian tube obstruction was done. Fifty animals were used. The continuum of mucoperiosteal changes from one day to six months after obstruction revealed gradual changes that were similar for each animal. Stages were defined, and by using different staining techniques, including immunocytochemistry, an overall middle ear defense system was postulated and documented. Nonspecific as well as specific defense systems, including localized immunity, were described. Effusions were studied in a continuum, and their pathogenesis was discussed.

A Longitudinal Study of Hearing and Middle Ear Status in Individuals With UCLP

2014 ◽  
Vol 35 (6) ◽  
pp. 989-996 ◽  
Author(s):  
Traci Flynn ◽  
Anette Lohmander
Keyword(s):  
Longitudinal Study ◽  
Middle Ear

Su1491 THE EFFECT OF STATINS ON RATE OF GROWTH, MALIGNANT TRANSFORMATION AND SURGICAL INTERVENTION OF PANCREATIC CYSTS: A 10-YEAR FOLLOW-UP STUDY

2020 ◽  
Vol 158 (6) ◽  
pp. S-601
Author(s):  
Motasem Alkhayyat ◽  
Mohannad Abou Saleh ◽  
Ashraf AlMomani ◽  
Alaa Habash ◽  
C. Roberto Simons-Linares ◽  
...  
Keyword(s):  
Malignant Transformation ◽  
Surgical Intervention ◽  
Pancreatic Cysts ◽  
Follow Up Study ◽  
Rate Of Growth

Rupture of the round Window Membrane

1976 ◽  
Vol 85 (1) ◽  
pp. 105-110 ◽  
Author(s):  
P. H. Taylor ◽  
P. G. Bicknell
Keyword(s):  
Middle Ear ◽  
Surgical Intervention ◽  
Round Window ◽  
Oval Window ◽  
Round Window Membrane ◽  
Physical Effort ◽  
Cochlear Aqueduct ◽  
Definite Improvement ◽  
History Of ◽  
Pressure Changes

A case of sudden deafness due to rupture of the round window membrane is presented. Nineteen similar cases have previously been reported in the literature. In a review of these twenty patients, it is noted that a history of concurrent physical effort or barotrauma was present in eighteen. This supports the view that the injury is produced by pressure changes acting either along the cochlear aqueduct (the explosive route) or, directly on the middle ear structures (the implosive route). At operation, the rupture may be difficult to see, and a separate leak from the oval window may be present. The timing of any surgical intervention is important. The authors recommend that this should be deferred for one week after the onset of symptoms, as the fistula may heal spontaneously. If no definite improvement has occurred at the end of this time, then tympanotomy should be undertaken during the next week.

scholarly journals Measuring Thickness of Middle Ear Mucosa Using MRI and CT Imaging versus Histopathology

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Mary Ann Nyc ◽  
Sang Gyoon Kim ◽  
Anil Kapoor ◽  
Timothy Jung
Keyword(s):  
Middle Ear ◽  
Ct Scanning ◽  
Vehicle Control ◽  
Ct Imaging ◽  
Control Group ◽  
Middle Ear Mucosa ◽  
Treatment Groups ◽  
Mri Scans ◽  
Mucosal Thickness ◽  
Temporal Bones

Objective. Otitis media (OM) is characterized by increased middle ear effusion and inflammation of middle ear tissue. In this study, we compared two radiographic methods of analyzing inflammation by measuring mucosal thickness (MT).Methods. 28 chinchillas were divided into three treatment groups consisting of a vehicle control group and two glucocorticoid groups. 6 underwent treatment by vehicle control, 10 were treated with ciprofloxacin 0.3%/dexamethasone 0.1% (DEX), and 10 received ciprofloxacin 0.2%/hydrocortisone 1% (HC). 96 hrs post-LPS inoculation, chinchillas were euthanized and their temporal bones were removed for analyses.Results. MRI scans (F=146.0861,P-value <0.0001) and histology (χ2=40.5267,P-value <0.0001) revealed statistically significant differences in MT measurements among treatment groups, whereas CT imaging did not. DEX-treated chinchillas exhibited overall significantly smaller MT values.Conclusion. Imaging MT was effective for determining severity of inflammation due to OM. Previous gold standard methods using histopathology compromise tissue integrity by chemical manipulation and dehydration effects. MRI and CT scanning are viable tools to preserve tissue and examine changes in MT. In this study, MRI provided more information about internal, soft tissue structures. In a clinical setting, MRI could be used for diagnosing and tracking severe or chronic OM.

scholarly journals Evolution of gray matter atrophy on serial MRI scans predicting the progression from MCI to Alzheimer's

2010 ◽  
Vol 6 (4) ◽  
pp. S300
Author(s):  
Gabriela Spulber ◽  
Eini Niskanen ◽  
Miia Kivipelto ◽  
Valtteri Julkunen ◽  
Merja Hallikainen ◽  
...  
Keyword(s):  
Gray Matter ◽  
Gray Matter Atrophy ◽  
Mri Scans ◽  
Serial Mri
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