Differentials and determinants of neonatal mortality in Pakistan: A cross sectional analysis (PDHS 2017-18)

2021 ◽  
pp. 1-14
Author(s):  
Asifa Kamal ◽  
Abeera Shakeel ◽  
Admin
Keyword(s):  
Neonatal Mortality ◽  
Hazard Model ◽  
Household Size ◽  
Multiple Births ◽  
Cox Proportional Hazard Model ◽  
Proportional Hazard ◽  
Proportional Hazard Model ◽  
Cross Sectional ◽  
Cox Proportional Hazard ◽  
Toilet Facility

Abstract Objective: To investigate differentials and determinants of neonatal mortality in Pakistan. Methods: Study design was cross sectional. Data from Pakistan Demographic and Health Survey (PDHS 2017-18) was used. Data collection period for PDHS 2017-18 was from 22 November 2017 to 30 April 2018. Neonatal mortality rates (NMRs) were computed to observe the differentials in NMR for various categories of socio-demographic factors. Cox proportional hazard model was fitted to identify significant factors affecting neonatal mortality. Results: Hazard of neonatal mortality had significantly decreased as household size increased (HR 0.41 and HR 0.36). Household with improved toilet facility had significantly lower chances (HR 0.57) of neonatal death as compared to that with unimproved toilet facility. Significantly elevated risk (HR 5.56) of neonate death was observed in case of multiple births. Children had better chances (HR 0.32; HR 0.34) of surviving in neonatal period as duration of birth spacing increased (24-35 months; 36 or more months). Conclusion: Household size, improved toilet facilities, multiple births and preceding birth intervals were found to have significant effect on neonatal mortality. Significant protective factors of neonate deaths were large household size, improved toilet facilities, singleton births and long birth interval. Keywords: PDHS 2017-18, Neonatal Mortality Rate, Cox Proportional Hazard Model

scholarly journals Delay of Detection Of COVID-19 Patients In Bangladesh; An Application To Cox Proportional Hazard Model

2020 ◽  
Author(s):  
Sujan Rudra ◽  
Shuva Das ◽  
Md. Ehsanul Hoque ◽  
Abul Kalam ◽  
Mohammad Arifur Rahman
Keyword(s):  
Risk Factors ◽  
Hazard Model ◽  
Laboratory Diagnosis ◽  
Cross Sectional Study ◽  
Cox Proportional Hazard Model ◽  
Proportional Hazard ◽  
Proportional Hazard Model ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Cox Proportional Hazard

Abstract Objective: To delineate the survival rate of the patients with coronavirus disease 2019 (COVID-19) who did the diagnostic tests lately after the development of symptoms. The aim is to determine the socio-demographic risk factors associated with the delay of the detection of COVID-19 patients. Methods: For this cross-sectional study, 300 patients were selected who were diagnosed as COVID-19 patients in the Molecular Biology Laboratory of Chittagong Medical College, Chattogram, Bangladesh. Data were collected from May to July 2020. Clinical characteristics were obtained from over phone interviews and laboratory diagnosis by Real-time Reverse Transcriptase Polymerase Chain Reaction (rRT-PCR). Cox proportional hazard model is applied to estimate risk factors affecting the delay of detection of COVID-19 patients.Result: Female mortality rate was 44.9% higher compared to males, graduates died 32% more than undergraduates, unmarried peoples’ death rate were 56% more than married and those who were in traveling irregularly and in contact with symptomatic patients, were 86% more died than non-travelers.Conclusion: Early diagnosis of COVID-19 can save a huge amount of lives and special attention should be emphasized on the significant explanatory variable.

scholarly journals Delay of Detection Of COVID-19 Patients In Bangladesh; An Application To Cox Proportional Hazard Model

2020 ◽  
Author(s):  
Sujan Rudra ◽  
Shuva Das ◽  
Md. Ehsanul Hoque ◽  
Abul Kalam ◽  
Mohammad Arifur Rahman
Keyword(s):  
Risk Factors ◽  
Hazard Model ◽  
Laboratory Diagnosis ◽  
Cross Sectional Study ◽  
Cox Proportional Hazard Model ◽  
Proportional Hazard ◽  
Proportional Hazard Model ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Cox Proportional Hazard

Abstract Objective: To delineate the survival rate of the patients with coronavirus disease 2019 (COVID-19) who did the diagnostic tests lately after the development of symptoms. The aim is to determine the socio-demographic risk factors associated with the delay of the detection of COVID-19 patients. Methods: For this cross-sectional study, 300 patients were selected who were diagnosed as COVID-19 patients in the Molecular Biology Laboratory of Chittagong Medical College, Chattogram, Bangladesh. Data were collected from May to July 2020. Clinical characteristics were obtained from over phone interviews and laboratory diagnosis by Real-time Reverse Transcriptase Polymerase Chain Reaction (rRT-PCR). Cox proportional hazard model is applied to estimate risk factors affecting the delay of detection of COVID-19 patients.Result: Female mortality rate was 44.9% higher compared to males, graduates died 32% more than undergraduates, unmarried peoples’ death rate were 56% more than married and those who were in traveling irregularly and in contact with symptomatic patients, were 86% more died than non-travelers.Conclusion: Early diagnosis of COVID-19 can save a huge amount of lives and special attention should be emphasized on the significant explanatory variable.

scholarly journals Determinants of Infant and Child Mortality in Bangladesh: Time Trends and Comparisons across South Asia

2014 ◽  
Vol 13 (4) ◽  
pp. 431-437 ◽  
Author(s):  
S C Karmaker ◽  
S Lahiry ◽  
D C Roy ◽  
B Singha
Keyword(s):  
Child Mortality ◽  
Birth Interval ◽  
Hazard Model ◽  
Cox Proportional Hazard Model ◽  
Proportional Hazard ◽  
Proportional Hazard Model ◽  
Wealth Status ◽  
Cox Proportional Hazard ◽  
Toilet Facility ◽  
Infant And Child Mortality

In spite of various effective intervention programs, the under-5 child mortality rate (U5MR) is still high in Bangladesh. The present paper focused on the levels, trends and determinants of U5MR in Bangladesh utilizing data from Bangladesh Demographic and Health Survey (BDHS), 2007. Differential pattern in U5MR in Bangladesh was examined using life table technique as a bi-variate analysis and Cox proportional hazard model was used to analyze the determinants of U5MR mortality. Data from BDHS (2007) showed that U5MR during the five years preceding the survey was 65 per 1,000 live births, i.e. one in fifteen children born in Bangladesh died before reaching the fifth birthday. The risk of dying in the first month of life (37 per 1,000) was nearly two and a half times greater than in the subsequent 11 months (15 per 1,000). Deaths in the neonatal period accounted for 57 percent of all under-five deaths. In the Cox proportional hazard model analysis, factors such as the place of residence, parent’s education, father’s working status, sources of drinking water, type of toilet facility, wealth status, watching of television, mother’s age, months of breastfeeding, birth interval had significant influence on infant and child mortality. The most significant predictors of neonatal, post-neonatal, infant and child mortality were residence, parent’s education, type of toilet facility, wealth status, watching TV, months of breastfeeding, and birth interval. Despite the improvement of medical technology, child mortality remained alarmingly high, indicating that demographic, socioeconomic, household and environmental conditions must be improved to substantially reduce child mortality in this population. DOI: http://dx.doi.org/10.3329/bjms.v13i4.20590 Bangladesh Journal of Medical Science Vol.13(4) 2014 p.431-437

scholarly journals A Study of Factors Affecting the Length of Hospital Stay of COVID-19 Patients by Cox-Proportional Hazard Model in a South Indian Tertiary Care Hospital

2021 ◽  
Vol 12 ◽  
pp. 215013272110002
Author(s):  
Gayathri Thiruvengadam ◽  
Marappa Lakshmi ◽  
Ravanan Ramanujam
Keyword(s):  
Hospital Stay ◽  
Tertiary Care ◽  
Length Of Hospital Stay ◽  
Hazard Model ◽  
Cox Proportional Hazard Model ◽  
Care Hospital ◽  
Proportional Hazard ◽  
Proportional Hazard Model ◽  
Cox Proportional Hazard ◽  
South Indian

Background: The objective of the study was to identify the factors that alter the length of hospital stay of COVID-19 patients so we have an estimate of the duration of hospitalization of patients. To achieve this, we used a time to event analysis to arrive at factors that could alter the length of hospital stay, aiding in planning additional beds for any future rise in cases. Methods: Information about COVID-19 patients was collected between June and August 2020. The response variable was the time from admission to discharge of patients. Cox proportional hazard model was used to identify the factors that were associated with the length of hospital stay. Results: A total of 730 COVID-19 patients were included, of which 675 (92.5%) recovered and 55 (7.5%) were considered to be right-censored, that is, the patient died or was discharged against medical advice. The median length of hospital stay of COVID-19 patients who were hospitalized was found to be 7 days by the Kaplan Meier curve. The covariates that prolonged the length of hospital stay were found to be abnormalities in oxygen saturation (HR = 0.446, P < .001), neutrophil-lymphocyte ratio (HR = 0.742, P = .003), levels of D-dimer (HR = 0.60, P = .002), lactate dehydrogenase (HR = 0.717, P = .002), and ferritin (HR = 0.763, P = .037). Also, patients who had more than 2 chronic diseases had a significantly longer length of stay (HR = 0.586, P = .008) compared to those with no comorbidities. Conclusion: Factors that are associated with prolonged length of hospital stay of patients need to be considered in planning bed strength on a contingency basis.

scholarly journals SMOKING STATUS AFFECTING SURVIVAL OF ADENOCARCINOMA LUNG CANCER PATIENTS IN KUALA LUMPUR, MALAYSIA

2017 ◽  
Vol 10 (9) ◽  
pp. 312
Author(s):  
Nida Sajid Ali Bangash ◽  
Natasha Hashim ◽  
Nahlah Elkudssiah Ismail
Keyword(s):  
Lung Cancer ◽  
Prognostic Significance ◽  
Hazard Model ◽  
Rank Test ◽  
Cox Proportional Hazard Model ◽  
Proportional Hazard ◽  
Kuala Lumpur ◽  
Proportional Hazard Model ◽  
Cox Proportional Hazard ◽  
Survival Difference

  Objective: Adenocarcinoma (AC) of the lung is now the most common histologic type of non-small cell lung cancer (NSCLC) worldwide since the past 20 years. This study was conducted to investigate survival difference among smoker and non-smoker lung AC patients.Methods: A retrospective observational study was conducted for 81 advanced NSCLC adult Malaysian patients in Radiotherapy and Oncology Clinic at Hospital Kuala Lumpur, Malaysia. A total of adult 30 Malaysian smokers and 51 non-smokers with lung AC were included. Ex-smokers were not included in the study. Demographic and clinical data were collected and described. For survival analysis, Kaplan–Meier test and log-rank test were used to calculate overall survival (OS) and analyse the difference in the survival curve. Cox proportional hazard model was used to identify prognostic significance of smoking status.Results: Non-smokers showed a significant association with female gender and Stage IV NSCLC. The median OS was higher for non-smokers (493 days) as compared to smokers (230 days). The Cox proportional hazard model showed higher hazard ratio for smokers.Conclusion: Non-smoking is an independent positive prognostic factor in lung AC.

scholarly journals Introduction of Two-Dose Mumps-Containing Vaccine into Routine Immunization Schedule in Quzhou, China, Using Cox-Proportional Hazard Model

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Zhiying Yin ◽  
Canjie Zheng ◽  
Quanjun Fang ◽  
Xiaoying Gong ◽  
Guoping Cao ◽  
...  
Keyword(s):  
Hazard Model ◽  
Routine Immunization ◽  
Cox Proportional Hazard Model ◽  
Proportional Hazard ◽  
Immunization Schedule ◽  
Proportional Hazard Model ◽  
Cox Proportional Hazard ◽  
Kaplan Meier ◽  
Routine Immunization Schedule ◽  
Different Doses

Mumps is a vaccine-preventable disease caused by the mumps virus, but the incidence of mumps has increased among the children who were vaccinated with one-dose measles-mumps-rubella (MMR) in recent years. In this study, we analyzed the influence of different doses of mumps-containing vaccine (MuCV) against mumps using Cox-proportional hazard model. We collected 909 mumps cases of children who were born from 2006 to 2010 and vaccinated with different doses of MuCV in Quzhou during 2006-2018, which were all clinically diagnosed. Kaplan-Meier survival methods and Cox-proportional hazard model were used to estimate the hazard probabilities. Kaplan–Meier curves showed that the cumulative hazard of male and female has no difference; lower hazards were detected among those who were vaccinated with two-dose MuCV, born in 2006, and infected after supplementary immunization activities (SIA). Cox-proportional hazard regression suggested that onset after SIA, born in 2006, and vaccinated with two-dose MuCV were protective factors against infection even after adjusting for potential confounding effects. Our study showed that it was necessary to revise the diagnostic criteria of mumps and identify RT-PCR as the standard for mumps diagnosis in China. We suggested that routine immunization schedule should introduce two doses of MMR and prevaccination screening should be performed before booster immunization in vaccinated populations.

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