Incidence of Involvement of Nipple Areola Complex in Breast Cancer

2015 ◽  
Vol 24 (Number 1) ◽  
pp. 33-38
Author(s):  
Md. R Hoq ◽  
A Sayeed ◽  
B Khan ◽  
R Parvin ◽  
S I Khan
Keyword(s):  
Breast Cancer ◽  
Care Center ◽  
Tertiary Care ◽  
Age Distribution ◽  
Oncologic Outcome ◽  
Breast Cancer Surgery ◽  
Breast Cancer Patients ◽  
Areola Complex ◽  
Areolar Complex ◽  
Study Population

In this prospective study, fifty cases of breast cancer were studied in a tertiary care center & different hospitals of Dhaka city for one year, aimed to determine the incidence of malignant involvement of NAC in breast cancer patients of our country with clinically uninvolved nipples from history and postoperative histopathological reports of mastectomy specimens. The age distribution of Breast cancer varied from 25 to 75 years. Highest incidence was in 5th and 6th decades numbering 30 (60%) cases. Incidence of 3rd decades was 8 (16%) cases and in 7th decades was 12 (24%) casesin relation to menstrual cycle Breast Ca incidence is more in post-menopausal women numbering 28 (56%).Lump size of most of the study population found within 2-Scm (T2 stage). Incidence of axillaty lymph node metastasis found positive in 28 patients (56%) and no metastasis in 22 patients (44%). Of 50 patients maximum no 22 (44%) found with moderately differentiated tumour, 16 (32%) patients found poorly differentiated, differentiation could not be assessed in 12 (24%) patient and well differentiated tumour found in only 2 (4%) patients. The most common histological type found in the study population is IDCC 44 (88%). Skin involvement was 0% and only 2% patients have malignant involvement of NAC from underling breast cancer. The conclusion in respect to this study is, Nipple areolar complex can be preserved with breast reconstruction in carefully selected patients going for breast cancer surgery with safe oncologic outcome.

scholarly journals Application of a domicile-based exercise program for shoulder rehabilitation after breast cancer surgery

2012 ◽  
Vol 20 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Eliana Louzada Petito ◽  
Afonso Celso Pinto Nazário ◽  
Simone Elias Martinelli ◽  
Gil Facina ◽  
Maria Gaby Rivero De Gutiérrez
Keyword(s):  
Breast Cancer ◽  
Experimental Study ◽  
Cancer Patients ◽  
Preoperative Evaluation ◽  
Exercise Program ◽  
Breast Cancer Surgery ◽  
Breast Cancer Patients ◽  
Quasi Experimental ◽  
Study Population

The aim of this study was to evaluate the effectiveness of an exercise program for the recuperation of the range of motion (ROM) of the shoulder. This is a quasi-experimental study developed at the Mastology Outpatient Clinic of the Federal University of São Paulo - Brazil, from August 2006 to June 2008, with 64 breast cancer patients undergoing surgery. The intervention consisted of: preoperative evaluation of the ROM, verbal and written guidance, demonstration and implementation of the exercises and revaluation at the outpatient follow-up appointments until the 105th postoperative day (PO). From the 7th PO a significant increase was observed in the ROM, which continued until the 105th PO. The minimum time for recovery was 105 days for the women undergoing mastectomy, and 75 days for those undergoing quadrantectomy. There was satisfactory adherence of 78.6% of the women. The domicile program was effective for the recovery of ROM in the study population, benefiting women who can not attend a presential program.

Toxicities and adherence rates of hormone treatment in male breast cancer patients treated at a tertiary care center

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e11613-e11613
Author(s):  
H. Visram ◽  
S. F. Dent
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Psychiatric Treatment ◽  
Negative Impact ◽  
Care Center ◽  
Tertiary Care ◽  
Male Breast ◽  
Breast Cancer Patients ◽  
Duration Of Treatment ◽  
Er Status

e11613 Background: Male breast cancer (BC) comprises approximately 1% of all breast cancer cases, and over 80% of male BC tumours express the estrogen receptor (ER). Male BC patients (pts) are often offered hormonal treatment (HT) with tamoxifen (T), or more recently aromatase inhibitors (AI's). There is a paucity of information in the literature on the toxicities (Tx) and adherence rates of HT in this population. Methods: We conducted a retrospective chart review of 24 pts diagnosed with male BC at the Ottawa Regional Cancer Centre from 1986–2003. Data collected included pt age, ER status, progesterone receptor (PR) status, systemic chemotherapy, HT, and Tx of treatment. Results: Median age of 24 male BC pts was 70.0 years (r: 46–83 years). The majority (16/24) of pts had ER/PR testing: 12 (75.0%) ER/PR +, 1 (6.3%) ER +/PR-, 2 (12.5%) ER +/PR unknown, and 1 (6.3%) ER/PR-. Of the 15 pts who were ER +, 13 received T and 5 received anastrozole (A) monotherapy during their treatment. One ER - pt received adjuvant T. Three pts with ER status unknown received T. Median duration of treatment with T (17 pts) was 38.0 months (r: 2–79 months). Hot flashes (23.5 %) was the most common reported Tx. Decreased libido, weight gain, rash, and malaise were reported in 2 pts (11.8%) each. Increased liver enzymes, pulmonary embolism, and erectile dysfunction were reported in 1 pt (5.9%) each. Five pts (29.4%) terminated treatment early due to T toxicity (median treatment 15 months; r: 2–54 months). Five pts were treated with A (median 10 months; r: 3–60 months), 4 of whom received prior T treatment. One pt reported loss of libido, and 1 significant depression /suicidal ideation requiring psychiatric treatment. Conclusions: This study provides contemporary data on toxicities and adherence rates of HT in male BC pts in a non-clinical trial setting. Approximately 30 % of male BC pts discontinued T therapy due to Tx, potentially having a negative impact on clinical outcome. Future studies will examine differences in adherence rates and outcomes between T and A in male BC pts. No significant financial relationships to disclose.

scholarly journals Histopathological spectrum of Cervical Lesion”– two and half Year prospective Study in Tertiary Care Center of Chhattisgarh, India

2021 ◽  
Vol 7 (2) ◽  
pp. 65-70
Author(s):  
Dr. Pratima Kujur ◽  
◽  
Dr. Chandrashekhar Indoria ◽  
Dr. S. Bagde ◽  
Dr. A. Tiwari ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Relative Frequency ◽  
Care Center ◽  
Tertiary Care ◽  
Age Distribution ◽  
Tertiary Care Center ◽  
Cervical Lesions ◽  
Indian Women ◽  
Common Cancer ◽  
Neoplastic Lesion

Introduction: Cervical lesions are the leading cause of morbidity in Indian women and cervicalcancer is the second most common cancer in women worldwide next to breast cancer. Objectives:To study the age distribution, the relative frequency of various cervical lesions and histopathologicalfeatures of cervical lesions. Materials and Methods: This is a two & half years retrospective studyof all cervical biopsies and hysterectomy specimens received from September 2017 to March 2020 inthe department of pathology. Result: In a total of 485 cases studied 359 (74.1%) cases were non-neoplastic, 107(22%) were preinvasive and 19 (3.9%) cases were malignant. Cervicitis was themost common non-neoplastic lesion and squamous cell carcinoma was the most common cancer.Conclusion: Our study highlights a vast spectrum of cervical lesions and therefore early detectionand management of certain lesions can help in reducing morbidity.

Breast cancer in young women in India.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e11506-e11506
Author(s):  
Sanjay P Deshmukh ◽  
Anupama Dutt Mane
Keyword(s):  
Breast Cancer ◽  
Triple Negative ◽  
Care Center ◽  
Tumour Size ◽  
Univariate Analysis ◽  
Tertiary Care ◽  
P Value ◽  
Breast Cancer Patients ◽  
Women In India

e11506 Background: The incidence of breast cancer is rising in India. It presents at a younger age in Indian population as compared to the western countries. Methods: This is a retrospective review of all breast cancer patients less than 40 years of age treated in single tertiary care center from June 2006 to June 2011. The aim was to assess the factors that may influence clinical outcome and prognosis including demographics, clinical characteristics, surgical and pathological findings and the treatment given. Clinical data was collected from medical records and histopathology reports. Independent variables like age, stage at presentation, surgery type, chemotherapy, radiation, tumour size, grade, nodal status, no. of positive nodes, perinodal extension, lymphovascular extension, ER, PR and Her2 neu were analysed. Results: Out of a total of 613 patients, 91 were under 40 years of age, corresponding to a prevalence of 14.8%. Median age was 35 years with the youngest being 23 years old. Maximum patients were in the age group of 36-40 years. Lymphovascular emboli was positive in 42 patients (48.8%) and perinodal extension was positive in 36 patients (41.8%). 30 patients(34.8%) had ER positivity, while 39 patients (45.3%) had PR positivity. Her 2 neu receptors were positive in 20 patients (23.2%). 39 patients were triple negative (45.3%). The median follow up period for all the patients was 28 months with the DFS being 76.1% and OS being 88.3%. In univariate analysis, factors significantly associated with survival were stage at presentation (p value- 0.026), presence of lymhovascular emboli (p value- 0.019) and presence of perinodal extension (p value- 0.007 ).Grade of the tumour also correlated with survival , however it was not statistically significant (p value- 0.086). Statistical analysis was done with SPSS 17. Conclusions: The incidence of breast cancer in younger women in India is high with increased number of triple negative patients. Overall survival is quite similar to that of the western population. Longer follow up and more studies are required to confirm this finding.

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