Automatic quality control of corpus callosum segmentations in large population studies

Author(s):  
William Javier García Herrera
2021 ◽  
Vol 127 ◽  
pp. 1-16
Author(s):  
Amir Hossein Poorjam ◽  
Mathew Shaji Kavalekalam ◽  
Liming Shi ◽  
Jordan P. Raykov ◽  
Jesper Rindom Jensen ◽  
...  

2021 ◽  
pp. 102219
Author(s):  
Simona Bottani ◽  
Ninon Burgos ◽  
Aurlien Maire ◽  
Adam Wild ◽  
Sebastian Strer ◽  
...  

Author(s):  
Josef Kauer-Bonin ◽  
Sunil K. Yadav ◽  
Ingeborg Beckers ◽  
Kay Gawlik ◽  
Seyedamirhosein Motamedi ◽  
...  

1998 ◽  
Vol 84 (1) ◽  
pp. 362-371 ◽  
Author(s):  
Roger G. Eston ◽  
Ann V. Rowlands ◽  
David K. Ingledew

Eston, Roger G., Ann V. Rowlands, and David K. Ingledew.Validity of heart rate, pedometry, and accelerometry for predicting the energy cost of children’s activities. J. Appl. Physiol. 84(1): 362–371, 1998.—Heart rate telemetry is frequently used to estimate daily activity in children and to validate other methods. This study compared the accuracy of heart rate monitoring, pedometry, triaxial accelerometry, and uniaxial accelerometry for estimating oxygen consumption during typical children’s activities. Thirty Welsh children (mean age 9.2 ± 0.8 yr) walked (4 and 6 km/h) and ran (8 and 10 km/h) on a treadmill, played catch, played hopscotch, and sat and crayoned. Heart rate, body accelerations in three axes, pedometry counts, and oxygen uptake were measured continuously during each 4-min activity. Oxygen uptake was expressed as a ratio of body mass raised to the power of 0.75 [scaled oxygen uptake (sV˙o 2)]. All measures correlated significantly ( P < 0.001) with sV˙o 2. A multiple-regression equation that included triaxial accelerometry counts and heart rate predicted sV˙o 2 better than any measure alone ( R 2 = 0.85, standard error of the estimate = 9.7 ml ⋅ kg−0.75 ⋅ min−1). The best of the single measures was triaxial accelerometry ( R 2 = 0.83, standard error of the estimate = 10.3 ml ⋅ kg−0.75 ⋅ min−1). It is concluded that a triaxial accelerometer provides the best assessment of activity. Pedometry offers potential for large population studies.


Despite improvement in diagnosis and management, cardiovascular disease (CVD) is the leading cause of death and hospitalization throughout the world. The expansion of digital cardiology presents outstanding opportunities for clinicians, researchers, and health care administrators to improve outcomes and sustainability of health systems. Electronic big health data combining electronic health records (EHRs) from diverse individuals across a wide variety of platforms may provide a real-time solution to questions and problems relating to health. Very large population studies based on EHR are efficient and cost-effective, and offer an alternative to traditional research approaches. Indeed, digital cardiology can help researchers to enhance, diagnose, and manage CVD using dedicated algorithms that allow targeted and personalized CVD treatments


Author(s):  
Burton H. Singer ◽  
Jürg Utzinger ◽  
Carol D. Ryff ◽  
Yulan Wang ◽  
Elaine Holmes

1990 ◽  
Vol 36 (11) ◽  
pp. 1871-1874 ◽  
Author(s):  
J S Hill ◽  
P H Pritchard

Abstract A simple procedure for phenotyping apolipoprotein (apo) E directly from plasma has been developed for use in the lipid clinic laboratory. In this new method, 10 microL of serum or plasma is pretreated with neuraminidase (EC 3.2.1.18), which removes the sialic acid residues from apo E and eliminates additional bands, thereby ensuring correct phenotype assignment. After a rapid delipidation step, the samples are focused in vertical polyacrylamide mini-slab gels and immunoblotted with a polyclonal goat anti-apo E antibody, followed by a Protein G-peroxidase conjugate. The accuracy of this method was confirmed by comparison with the established procedure of phenotyping by isoelectric focusing of delipidated very-low-density lipoprotein. In addition, sera from 203 subjects from Vancouver, selected without conscious bias, were used to determine the local distribution of the apo E alleles. We estimate that the relative frequencies of apo E alleles epsilon 2, epsilon 3, and epsilon 4 in this population are 0.086, 0.761, and 0.153, respectively. The speed and convenience of using minigels make this procedure ideal for clinical laboratory applications and large population studies.


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