Coffee Consumption Reduces Mortality in Patients with Acute Myocardial Infarction

Aim: Acute myocardial infarction (AMI) is the number one cause of death in 2000. Usually, coffee restriction was advised to patients with cardiovascular diseases. Recent studies indicate coffee might have a cardioprotective effect.Method: Systematic search was done on Pubmed and Cochrane. Title and abstract screening were initiated on 12 articles, followed by selection with inclusion and exclusion criteria, and selected one meta-analysis study to be critically appraised. Result: The meta-analysis study appraised resulted with a good score. Reduction in mortality rate was found, and an inverse relationship was concluded between heavy coffee consumption versus no consumption and mortality in acute myocardial infarction patients. RR = 0.54 95% CI [0.45 – 0.65].Conclusion: Coffee consumption and mortality in myocardial infarction patients have an inverse relationship, with the highest risk reduction found in heavy coffee drinkers.

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Vasopressors and Inotropes in Acute Myocardial Infarction Related Cardiogenic Shock: A Systematic Review and Meta-Analysis

Journal of Clinical Medicine ◽

10.3390/jcm9072051 ◽

2020 ◽

Vol 9 (7) ◽

pp. 2051 ◽

Cited By ~ 1

Author(s):

Mina Karami ◽

Veemal V. Hemradj ◽

Dagmar M. Ouweneel ◽

Corstiaan A. den Uil ◽

Jacqueline Limpens ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Cardiogenic Shock ◽

Case Reports ◽

Meta Analysis ◽

Control Group ◽

Exclusion Criteria ◽

And Control ◽

Post Cardiac Surgery

Vasopressors and inotropes are routinely used in acute myocardial infarction (AMI) related cardiogenic shock (CS) to improve hemodynamics. We aimed to investigate the effect of routinely used vasopressor and inotropes on mortality in AMI related CS. A systematic search of MEDLINE, EMBASE and CENTRAL was performed up to 20 February 2019. Randomized and observational studies reporting mortality of AMI related CS patients were included. At least one group should have received the vasopressor/inotrope compared with a control group not exposed to the vasopressor/inotrope. Exclusion criteria were case reports, correspondence and studies including only post-cardiac surgery patients. In total, 19 studies (6 RCTs) were included, comprising 2478 CS patients. The overall quality of evidence was graded low. Treatment with adrenaline, noradrenaline, vasopressin, milrinone, levosimendan, dobutamine or dopamine was not associated with a difference in mortality between therapy and control group. We found a trend toward better outcome with levosimendan, compared with control (RR 0.69, 95% CI 0.47–1.00). In conclusion, we found insufficient evidence that routinely used vasopressors and inotropes are associated with reduced mortality in patients with AMI related CS. Considering the limited evidence, this study emphasizes the need for randomized trials with appropriate endpoints and methodology.

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Faculty Opinions recommendation of Intra-aortic Balloon Pump Therapy for Acute Myocardial Infarction: A Meta-analysis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725411004.793508710 ◽

2015 ◽

Author(s):

André Coetzee

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Meta Analysis ◽

Pump Therapy ◽

Intra Aortic Balloon Pump

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Incidence and risk factors of delirium after percutaneous coronary intervention in individuals hospitalised for acute myocardial infarction: protocol for a systematic review and meta-analysis

BMJ Open ◽

10.1136/bmjopen-2020-044564 ◽

2020 ◽

Vol 10 (12) ◽

pp. e044564

Author(s):

Kaizhuang Huang ◽

Jiaying Lu ◽

Yaoli Zhu ◽

Tao Cheng ◽

Dahao Du ◽

...

Keyword(s):

Risk Factors ◽

Myocardial Infarction ◽

Systematic Review ◽

Acute Myocardial Infarction ◽

Percutaneous Coronary Intervention ◽

Risk Factor ◽

Meta Analysis ◽

Coronary Intervention ◽

Cochrane Library ◽

Percutaneous Coronary

IntroductionDelirium in the postoperative period is a wide-reaching problem that affects important clinical outcomes. The incidence and risk factors of delirium in individuals with acute myocardial infarction (AMI) after primary percutaneous coronary intervention (PCI) has not been completely determined and no relevant systematic review and meta-analysis of incidence or risk factors exists. Hence, we aim to conduct a systematic review and meta-analysis to ascertain the incidence and risk factors of delirium among AMI patients undergoing PCI.Methods and analysesWe will undertake a comprehensive literature search among PubMed, EMBASE, Cochrane Library, PsycINFO, CINAHL and Google Scholar from their inception to the search date. Prospective cohort and cross-sectional studies that described the incidence or at least one risk factor of delirium will be eligible for inclusion. The primary outcome will be the incidence of postoperative delirium. The quality of included studies will be assessed using a risk of bias tool for prevalence studies and the Cochrane guidelines. Heterogeneity of the estimates across studies will be assessed. Incidence and risk factors associated with delirium will be extracted. Incidence data will be pooled. Each risk factor reported in the included studies will be recorded together with its statistical significance; narrative and meta-analytical approaches will be employed. The systematic review and meta-analysis will be presented according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.Ethics and disseminationThis proposed systematic review and meta-analysis is based on published data, and thus there is no requirement for ethics approval. The study will provide an up to date and accurate incidence and risk factors of delirium after PCI among patients with AMI, which is necessary for future research in this area. The findings of this study will be disseminated through publication in a peer-reviewed journal.PROSPERO registration numberCRD42020184388.

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