Clinical Nursing of Tibetan Medicine "Xiuqun Enbao Powder" for Vaginal Lavage Combined with "Wine Leaching Stone" for Pelvic Inflammation

2021 ◽  
VASA ◽  
2005 ◽  
Vol 34 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Brunner-La Rocca ◽  
Schindler ◽  
Schlumpf ◽  
Saller ◽  
Suter

Background: Previous studies showed an anti-atherosclerotic effect of PADMA 28, an herbal formula based on Tibetan medicine. As the mechanisms of action are not fully understood, we investigated whether PADMA 28 may lower blood lipids and lipid oxidisability, and affect early endothelial dysfunction. Patients and methods: Sixty otherwise healthy subjects with total cholesterol ≥5.2 mmol/l and < 8.0 mmol/l were randomly assigned to placebo or PADMA 28, 3 x 2 capsules daily, for 4 weeks (double-blind). Blood lipids (total, LDL-, and HDL-cholesterol, triglycerides, Apo-lipoprotein A1 and B) and ex vivo lipid oxidisability were measured before and after treatment. In a subset of 24 subjects, endothelial function was assessed using venous occlusion plethysmography with intraarterial infusion of acetylcholine. Isolated LDL and plasma both untreated and pre-treated with PADMA 28 extract were oxidised by the radical generator AAPH. Conjugated diene formation was measured at 245 nm. Results: Blood lipids did not change during the study in both groups. In contrast to previous reports in mild hypercholesterolaemia, no endothelial dysfunction was seen and, consequently, was not influenced by therapy. Ex vivo blood lipid oxidisability was significantly reduced with PADMA 28 (area under curve: 5.29 ± 1.62 to 4.99 ± 1.46, p = 0.01), and remained unchanged in the placebo group (5.33 ± 1.88 to 5.18 ± 1.78, p > 0.1). This effect persisted one week after cessation of medication. In vitro experiments confirmed the prevention of lipid peroxidation in the presence of PADMA 28 extracts. Persistent protection was also seen for LDL isolated from PADMA 28-pretreated blood after being subjected to rigorous purification. Conclusions: This study suggests that the inhibition of blood lipid oxidisability by PADMA 28 may play a role in its anti-atherosclerotic effect.


Pflege ◽  
2000 ◽  
Vol 13 (3) ◽  
pp. 133-138 ◽  
Author(s):  
Georges Evers

Pflege als Dienstleistung hat eine lange Tradition, Pflegeforschung dagegen eine verhältnismäßig kurze Geschichte. Die erste Fachveröffentlichung stammt von Florence Nightingale aus dem Jahr 1858. Seit Nightingale hat sich das Bedürfnis, zu forschen und die Effektivität von Pflegediensten zu erhöhen, gesteigert. Mehr als zuvor benötigt die Gesellschaft auf wissenschaftlicher Evidenz basierende Pflege, die nicht nur auf Traditionen und Ritualen verharrt. Die Basis von wissenschaftlicher Erkenntnis kann durch Forschung erworben werden. Dabei ist es wichtig, innerhalb der multidisziplinären klinischen Forschung das besondere Interesse der Pflege klar im Mittelpunkt zu halten. Virginia Henderson (1955) und Dorothea Orem (1959) haben die eigentliche Aufgabe der Pflege klar festgesetzt. Das Design klinischer Pflegeforschung kann (quasi-)experimentell, korrelativ oder deskriptiv sein. Deskriptive Forschung kann qualitativ oder quantitativ sein. Experimentelle oder quasi-experimentelle Studien dienen der Erforschung von Auswirkungen von Pflegeunterstützung zur Verringerung von Selbstpflegenöten und Verbesserung der Selbstpflegekompetenz von Patienten. Einige Beispiele von klinischer Pflegeforschung werden gegeben. Das erste Beispiel zeigt, wie Pflegepersonalbesetzung und die Qualität der Pflege Auswirkungen auf die Selbstpflegefähigkeit bei der Hygiene haben. Das zweite Beispiel zeigt, wie Selbstpflege und Lebensqualität bei Krebspatienten unter Chemotherapie zusammenhängen. Das dritte Beispiel zeigt, welche Auswirkungen Diabetes-Aufklärung auf Selbstpflegeverhalten und Stoffwechselkontrolle hat. Die angeführten Beispiele und Argumentationen zeigen die Wichtigkeit klinischer Pflegeforschung mit klarem Pflegefokus. Dies bedeutet, Forschungsprogramme zu entwerfen, und setzt Kooperation mit Pflegediensten, Ärzten und Krankenhäusern voraus. Erkenntnisse sind im Interesse evidenter Patientenversorgung multidisziplinär zu diskutieren und zu nutzen.


1991 ◽  
Author(s):  
Martha R. Bell ◽  
Patricia Twist ◽  
Terry R. Misener

Author(s):  
Ruihuan Pan ◽  
Shanshan Ling ◽  
Haodong Yang ◽  
Yan Huang ◽  
Lechang Zhan ◽  
...  

Background: Shoulder-hand syndrome (SHS) refers to a syndrome causing sudden edema, shoulder pain and limited hand function. Qingpeng ointment, a kind of Tibetan medicine, can reduce swelling, relieve pain, tonify stagnation and clear the meridians, which is consistent with the pathological mechanism of SHS after stroke. Therefore, if clinical trials can be used to explore the effectiveness of Qingpeng ointment for treatment of poststroke SHS and promote its application in clinical medicine, this is of specific significance for the treatment of poststroke SHS. Objective: To investigate the clinical efficacy and safety of Qingpeng ointment in the treatment of poststroke SHS. To provide an objective basis for a better therapeutic treatment for poststroke SHS. Method: A prospective, randomized, controlled study was conducted. This study recruited 120 patients with poststroke SHS who met the inclusion criteria. They were randomized into the treatment group and the control group, with 60 patients allocated to each group. The treatment group received routine medical treatment and rehabilitative care after using the Qingpeng ointment, while the patients in the control group received only routine treatment without the ointment. All patients received clinical assessment with the Visual Analogue Scale (VAS), measurement of the range of motion (ROM) of the upper-limb joints, the Fugl-Meyer Assessment of Upper Extremity (FMA-U) and the Modified Barthel Index Score (MBI) before and after the whole treatment. Results: After 4 weeks of treatment, the VAS scores of both groups were decreased significantly (P<0.05), and the difference between the two groups was statistically significant (P < 0.05). There is no statistical significance for the difference between the treatment group and control group in terms of the FMA-U and MBI scores and the forward bend, backward, outstretch, external rotation and pronation angles after treatment. The increases in the values of VAS, FMA-M and MBI in the treatment group were greater than those in the control group, and the difference was statistically significant (P < 0.05). The increases in the values of the forward bend, outreach and external rotation angles in the treatment group were greater than those in the control group, and the difference was statistically significant (P < 0.05). Conclusion: The treatment group showed better results than the control group in terms of the relief of pain symptoms, the improvement of motor function and the improvement of the activities of daily living for patients with shoulder-hand syndrome after cerebral hemorrhage. Qingpeng ointment is effective and safe in treating poststroke SHS.


2021 ◽  
Vol 13 (2) ◽  
pp. 202-209
Author(s):  
Ying-hui Bai ◽  
Dong-xu Shi ◽  
Hong-yu Lu ◽  
Kun-bao Yang ◽  
Huan-hu Zhao ◽  
...  

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