Comparison of Umbilical Arterial and Venous Lactate and Base Excess Values and Its Neonatal Outcome in High-risk Pregnancies

Background: Placenta plays a very important role in the growth and development of fetus. Objective: To know the correlation between placental weight and perinatal outcome in term antenatal women. Methods: Present prospective case-control study was conducted in the rural tertiary center of Northern India over one year (January-December 2018) on 1,118 term (≥37-≤42 weeks) antenatal women with singleton pregnancy fulfilling inclusion criteria with 559 women with high-risk pregnancy as cases and 559 low-risk pregnant women as controls. Placental weight, birth weight was measured immediately after delivery and compared between the two groups along with gestation, parity, fetal gender, and neonatal outcome. Statistical analysis was done using SPSS 22 version. Results: Mean placental weight [481.98±67.83 gm vs. 499.47±59.59 gm (p=.000)] and birth weight [2.68±0.53 Kg vs. 2.88±0.4 Kg (p=.000)] was significantly lower in high risk as compared to lowrisk participants, whereas placental birth weight ratio was higher in high-risk cases [18.35±2.37 vs. 17.41±1.38 (p=.000)] respectively. Placental weight was positively correlated with birth weight and placental weight and birth weight increased with increasing gestation in both cases and controls. Male neonates had higher placental weight [492.74±68.24 gm vs. 488±58.8 gm (p=0.224)] and birth weight [2.81±0.5 Kg vs. 2.74±0.45 Kg (p=0.033)] as compared to females. Neonatal Intensive Care Unit admission was significantly associated with low placental and birth weight (p=.000). Conclusion: There is a significant correlation between placental weight, birth weight and neonatal outcome, hence placental weight can be used as an indirect indicator of intrauterine fetal growth.

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Neonatal Outcome in High Risk Pregnancies

Journal of Neonatology ◽

10.1177/0973217920150406 ◽

2015 ◽

Vol 29 (4) ◽

pp. 23-30

Author(s):

Simranjeet Singh ◽

Karuna Thapar ◽

Madhu Nagpal

Keyword(s):

High Risk ◽

Neonatal Outcome

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1160 Effect of Cervical Colonization on Neonatal Outcome in High Risk Pregnancies: Results From a Tertiary Maternity Center in Turkey

Archives of Disease in Childhood ◽

10.1136/archdischild-2012-302724.1160 ◽

2012 ◽

Vol 97 (Suppl 2) ◽

pp. A332-A333

Author(s):

M. Oncel ◽

S. Celen ◽

G. Demirel ◽

F. Canpolat ◽

E. Calisici ◽

...

Keyword(s):

High Risk ◽

Neonatal Outcome

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Impact of Intrapartum Cardiotocographic Monitoring on Neonatal Outcome in High Risk Pregnancies

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2020/346 ◽

2020 ◽

Vol 7 (33) ◽

pp. 1657-1661

Author(s):

Kumudini Pradhan ◽

Pranati Pradhan ◽

Lipsa Patra

Keyword(s):

High Risk ◽

Neonatal Outcome

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Predictive value of fetal scalp pH and base excess for fetal acidosis and poor neonatal outcome

The Journal of Maternal-Fetal & Neonatal Medicine ◽

10.1080/14767058.2017.1365132 ◽

2017 ◽

Vol 31 (23) ◽

pp. 3166-3171 ◽

Cited By ~ 3

Author(s):

Panagiotis Tsikouras ◽

Zacharoula Koukouli ◽

Barbara Niesigk ◽

Bachar Manav ◽

George Farmakides ◽

...

Keyword(s):

Predictive Value ◽

Base Excess ◽

Neonatal Outcome ◽

Fetal Scalp ◽

Fetal Acidosis

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Comparative efficacy of admission cardiotocography in high risk and low risk pregnancies in predicting neonatal outcome

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20213844 ◽

2021 ◽

Vol 10 (10) ◽

pp. 3823

Author(s):

Gurpreet Kaur Nandmer ◽

Shivangi Jaiswal ◽

Pooja Namdeo

Keyword(s):

High Risk ◽

Predictive Value ◽

Neonatal Outcome ◽

Low Risk ◽

Comparative Efficacy ◽

Risk Pregnancy ◽

Risk Patients ◽

Nicu Admission ◽

Fetal Wellbeing ◽

Sensitivity Specificity

Background: Admission cardiotocography (CTG) is a test of fetal wellbeing performed during labor. A normal CTG is for 20-30 minutes and ranges from 110-160 bpm with beat to beat variability, two accelerations and no decelerations with two contractions (as per NICE 2018 guidelines). To study comparative efficacy of admission CTG in predicting neonatal out in high risk, low risk and universally in all pregnancy.Methods: All high risk as well as low risk patients coming to labor room in labor were included in the study. CTG print was taken, and neonatal outcome as NICU admission were noted after taking written consent.Results: 189 cases were taken.138 were high risk cases, CTG was taken: 91were reassuring, 47were abnormal (non-reassuring +abnormal). In terms of NICU admission, 21 and 26 neonates were admitted. Out of 51 low risk cases, 33 had reassuring CTG, and18 had abnormal; 7and 6 was the number of NICU admission, respectively. When compared, highest sensitivity, specificity and positive predictive value of 55.31%, 77% and 55.3% was seen in high risk pregnancy, whereas negative predictive value (78.8%) was slightly higher in low risk cases.Conclusions: Admission CTG is a good predictor of neonatal outcome. Its predictive efficacy is more in high risk cases. It’s practicality in revealing poor neonatal outcome is more.

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A study to evaluate pregnancy with maternal heart disease: a prospective observational study at a tertiary care centre in India

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20211150 ◽

2021 ◽

Vol 10 (4) ◽

pp. 1637

Author(s):

Khushboo Goel ◽

Sanjaykumar G. Tambe

Keyword(s):

Heart Disease ◽

High Risk ◽

Observational Study ◽

Maternal Mortality ◽

Prospective Observational Study ◽

Neonatal Outcome ◽

Risk Group ◽

High Risk Group ◽

Heart Disease In Pregnancy ◽

In Pregnancy

Background: Prevalence of heart disease in pregnancy vary from 0.3-3.5%. Normal pregnancy is associated with physiological cardiovascular changes. These changes may unmask underlying cardiac disease in normal women and increase morbidity and mortality in women with heart disease. Heart disease in pregnancy is an important cause of maternal mortality in India. The aim of this study was to evaluate the maternal and neonatal outcome of pregnancy with heart disease.Methods: A prospective observational study was conducted at Sassoon General Hospital, Pune, India. 75 patients who fulfilled the inclusion criteria were studied. Maternal and neonatal outcome were analyzed.Results: Maternal heart disease was classified into congenital (36%) and acquired (64%). In acquired variety, rheumatic heart disease was most commonly seen. In congenital, ASD was most common. We divided the cases into two groups based on their NYHA status, low risk group had 74.67% patients and high risk group had 25.33% patients. The most common antenatal complication was PROM (41.3%). There was statistically significant association between ICU admission and high-risk group. The most common neonatal complications were IUGR and prematurity. Maternal mortality rate in the study group was 6.6%.Conclusions: The perinatal outcome of heart disease in pregnancy is more dependent on the severity of symptoms rather than the duration and type of heart disease. Multidisciplinary evaluation is necessary. Suboptimal optimization of the heart condition in the antenatal period and delayed referral were the major risk factor for maternal mortality.

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